Researchers at NCBS have discovered how 3D environments impact bacterial growth. Using 3D models that mimic natural environments like soil and mucus, the study revealed that the shape of bacteria significantly affects their ability to flourish in these complex settings. This research challenges the traditional 2D lab methods and sheds light on bacterial behavior in more realistic conditions.
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BENGALURU: A new study from the National Centre for Biological Sciences (NCBS) has uncovered how 3D environments influence bacterial growth and survival. By using 3D models to mimic natural settings such as mucus and soil, researchers found that the shape of bacteria plays a crucial role in their ability to thrive in complex environments.
For more than 300 years, scientists have studied bacteria in the lab, for which they primarily use liquid cultures or flat 2D plates.
An in vitro 3D growth matrix with tunable viscoelastic properties | Credit: NCBS
An in vitro 3D growth matrix with tunable viscoelastic properties | Credit: NCBS

While this is convenient and has been invaluable for biological research, it does not reflect natural 3D environments like soil, mucus, or plant and animal tissues.
As a result, little is known about bacterial growth in these complex settings with varying material properties
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