Farmington, May 11, 2023 (GLOBE NEWSWIRE) -- The Global Humanized Mice Model Market size was valued at USD 95.72 Million in 2022 and is projected to reach USD 188.57 Million by 2030, growing at a CAGR of 9.54% from 2023 to 2030. To maintain the physiological expression and modulation of the human gene inserted into the mouse genome, the model necessitates precise risk assessment and exhaustive analysis. To determine the optimal expression and functionality of the human protein in a mouse environment, the structure and accuracy of the mouse and human genes and proteins are analyzed. In biomedical research, including cancer biology, regenerative medicine, human hematopoiesis, infectious diseases, transplantation, and autoimmunity, humanized rodent models are utilized.
Segmentation Overview:
Type Outlook:
Green chelates/natural chelating agents are extensively used in cleaning applications. This application is segmented into household cleaning and industrial cleaning. Household cleaning includes automatic dishwashing, laundry detergents, hand dishwashing, and surface cleaning. Industrial cleaning includes mechanical dishwashing, transport cleaning, hard surface cleaning, biocidal detergents, and metal cleaning.
Green chelates/natural chelating agents are used in automatic dishwashing to prevent scale formation on the heating element of the machine. In addition, the use of green chelates/natural chelating agents suppresses filming and spotting, especially, in the rinse phase. Green chelates/natural chelating agents also boost the effectiveness of biocides.
Application Outlook:
The global market is segmented by application into detergent, personal care, pulp & paper, chemicals, food & beverage, and others. Sodium gluconate is the sodium salt of gluconic acid produced by fermentation of glucose. It is predominately used for technical applications as an effective set retarder and plasticizer in concrete admixtures, as well as a chelating agent for calcium and magnesium ions in industrial, institutional, and household cleaning products. In personal care products, sodium gluconate is used as a chelating agent (replacement of EDTA) as well as a powerful moisturizing ingredient. Use of sodium gluconate in food applications such as in formulation of high-intensity sweeteners, mineral salts, and cleaning operations of food processing equipment has increased, thus driving its demand.
Regional Analysis:
North America holds the majority share, accounting for 41.5% revenue of the global humanized mouse models market in 2022. This large share is due to increased R&D spending by pharmaceutical companies and increased biomedical research. Presence of prominent market players in the region and developments in the pharmaceutical and research sectors are likely to be the main drivers.
According to recent research publications, rat and mouse models cover 99.3% of mammals used in 16 large US organizations. Therefore, high consumption rates of these models in these regions fuel revenue growth. North America has witnessed tremendous technological advances that have led to the development of transgenic mice, knock-in mice, and knock-out mice.
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Scope of Report:
| Report Attributes | Details |
| Growth Rate | CAGR of 9.54% from 2023 to 2030. |
| Revenue Forecast by 2030 | USD 188.57 Million |
| By Type |
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| By Application |
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| By Industries |
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| By Companies |
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| Regions and Countries Covered |
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| Base Year | 2022 |
| Historical Year | 2017 to 2022 |
| Forecast Year | 2023 to 2030 |
Market Dynamics:
Drivers and Restraints:
Drivers
The humanized mouse model market is poised to rise due to the increasing demand for personalized medicines designed using animal models, especially mouse models. Human tissues are transplanted into immunodeficiency models and disease manifestations are registered. Then, to find the most suitable treatment, the model is treated with various drugs or gene therapy to provide suitable or customized drugs to the patient, increasing the factors that will influence the global market.
Challenges
Despite numerous drivers, the high cost of humanized models is one of the major impediments limiting their use in trials, as humanized models used in trials can cost thousands of dollars even for a single patient. Additionally, using humanized models in government-funded basic research is too costly, which may challenge regional market growth.
Key Segments Covered:
Top Market Players:
- Ingenious Targeting Laboratory
- Axen
- rans Genic Inc.
- Horizon Discovery Group PLC
- HuMurine Technologies
- Champions Oncology Inc.
- Trans Genic Inc.
- Crown Bioscience Inc.
- Others.
By Type
- Humanized Mouse Models
- Humanized Rat Models
By Application
- Pharmaceutical & Biotechnology Companies
- Contract Research Organizations
- Academic & Research Institutions
By Industries
- Government
- Healthcare
- Retail
- Manufacturing
- Others
- BFSI
- IT and telecom
Regions and Countries Covered
- North America: (US, Canada, Mexico, Rest of North America)
- Europe: (Germany, France, Italy, Spain, UK, Nordic Countries, Benelux Union, Rest of Europe)
- Asia-Pacific: (Japan, China, India, Australia, South Korea, Southeast Asia, Rest of Asia-Pacific)
- The Middle East & Africa: (Saudi Arabia, UAE, Egypt, South Africa, Rest of the Middle East & Africa)
- Latin America: (Brazil, Argentina, Rest of Latin America)
- Rest Of the World
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