The NYPD is investigating a suspicious powder found Wednesday afternoon inside the mail room at the Manhattan District Attorney’s office in Lower Manhattan, according to police.

Cops responded around 3:10 p.m. to a 911 call of a suspicious powder found in the basement mail room at 80 Centre St. — the second such incident amid DA Alvin Bragg’s high-profile case against former President Donald Trump.

There were no reported injuries and no one evacuated, police said.

Officers were still investigating the powder’s contents on Wednesday afternoon, according to cops.

Last month, the Lower Manhattan courthouses were thrown into a frenzy when white powder was discovered in an envelope marked “Alvin” with a return address for “Donald Trump,” law enforcement sources previously told the Daily News.

This is a developing story.