Rapid influenza tests may reduce antibiotic prescriptions, improve patient outcomes
Rapid influenza diagnostic tests (RIDTs) may reduce antibiotic prescriptions, improve patient outcomes suggests a new study published in the Clinical Infectious Diseases
They compared patients with acute respiratory infection (ARI) symptoms who received an RIDT and patients who did not at 2 urgent care facilities. Primary analysis using 1-to-1 exact matching resulted in 1145 matched pairs to which McNemar 2 × 2 tests were used to assess the association between the likelihood of prescribing, imaging/laboratory ordering, and RIDT use. Secondary analysis compared the same outcomes using logistic regression among the RIDT-tested population between participants who tested negative (RIDT(−)) and positive (RIDT(+)).
Results
Primary analysis revealed that compared to the non-RIDT-tested population, RIDT(+) patients were more likely to be prescribed antivirals and less likely to be prescribed antibiotics
Comparing RIDT-tested to non-RIDT-tested participants, RIDT use increased antiviral prescribing odds and reduced antibiotic prescribing odds
Secondary analysis identified increased odds of prescribing antivirals and decreased odds of prescribing antibiotics for RIDT(+) participants compared with RIDT(−).
Use of rapid influenza diagnostic tests (RIDTs) in patients presenting with acute respiratory infection (ARI) symptoms influences clinician diagnostic and treatment decision-making, which could lead to improved patient outcomes, population-level reductions in influenza burden, and a decreased threat of antibiotic resistance.
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