Earlier, stand-in skipper Moeen Ali hit a quickfire fifty to help England establish a formidable total of 199/5 against Pakistan. Moeen Ali hit four sixes and four fours in his 23-ball 55 not out after England won the toss and chose to bat first at National Stadium.
Youngster Harry Brook also played a 31-run cameo to keep England ticking after the dismissals of Phil Salt and Ben Duckett.
Duckett had ramped his way to a 22-ball 43, before Nawaz gave him his marching orders. Shahnawaz Dahani had earlier struck twice in the powerplay to dismiss Alex Hales and Dawid Malan off consecutive deliveries.
England, who are on their first tour of Pakistan in 17 years, won the first game by six wickets.