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A four-alarm tire tore through a Brooklyn apartment building, leaving six firefighters hurt and a dozen people homeless on Thanksgiving.

The three-story apartment building located at 65 Devoe Street in Brooklyn's Williamsburg neighborhood went up in flames around 11.15pm on Thursday.

Forty firefighting units and 170 personnel responded to the call.

The firefighters arrived to find the top floor of the building completely engulfed in flames, according to ABC 7. 

After more than two and a half hours four apartments were gutted, leaving 12 residents homeless.

A four-alarm tire tore through a three-story Brooklyn apartment building, leaving a dozen people homeless on Thanksgiving

The blaze engulfed four residential units at 65 Devoe Street in Brooklyn's Williamsburg neighborhood

The fire spread to the attic and crumbled the roof. Footage of the fire showed the top floor completely blackened and charred 

Firefighters responded to the call just after 11.15pm Thursday and had the fire under control around 1.49am

The rapidly-spreading flames grew larger throughout the night and also burnt a tree planted in front of the building

Six firefighters were also rushed to the hospital to be treated for minor injuries but they are all expected to recover, according to ABC.

FDNY Assistant Chief Tom Currao told the news station that four residential units were affected and no civilians were injured.

'We're working with NYC Emergency Management on relocation for those residents,' he told ABC. 

The 12 displaced residents were temporarily relocated to area hotels throughout the city with the help of American Red Cross, as reported by News 12. 

The department is investigating the cause of the fire, which also charred the siding of the neighboring building.

Videos circulating social media showed the fast-moving blaze. 

 Videos circulating social media captured huge flames engulfing the apartment building

The FDNY is investigating the cause of the fire, which also charred the siding of the neighboring building

Forty firefighting units and 170 personnel responded to the call on Thursday night

Firefighters were pictured putting out the last of the fire in the early hours of Friday morning

Six firefighters were taken to the hospital to be treated for minor injuries but they are all expected to recover

Firefighters were seen in tower ladders as flames and thick black smoke poured out of the top-floor windows and the structure began to crumble.

The fire reportedly spread to the attic and crumbled the roof of the building before subsiding around 1.49am.

Once the fire was put out, more footage showed personnel investigating the top floor, which was completely blackened by smoke and soot. 

The fire came after 18 New York City fire companies out of 300 were out of service as a result of the vaccine mandate that came into effect and forced supervisors to send home unvaccinated firefighters.

Earlier this month, at least one crew of eight from FDNY Engine 243 in Brooklyn was told to go home and another ten units were down in Williamsburg, East New York, Brownsville, Sunset Park and Flatbush. 

The flames were filmed billowing out of the top-floor windows as they crumbled the roof of the structure

The 12 displaced residents were temporarily relocated to area hotels throughout the city with the help of American Red Cross

Videos from the scene captured the aftermath of the fire. The top of the building and a nearby tree were heavily charred

Firefighters also investigated the neighboring building and the cause of the fire has yet to be determined