Chelsea host Southampton at Stamford Bridge for the second time in a month when the two sides meet in the Carabao Cup this evening.
The two clashed in the Premier League at the start of October with the Blues needing two late goals to run out 3-1 winners.
The Saints will be out for revenge having been level with 15 minutes remaining before captain James Ward-Prowse was shown a red card.
But they face a tough task to reach the next round and take on a Chelsea side who put seven past a helpless Norwich on Saturday.
Chelsea vs Southampton: talkSPORT commentary
The Carabao Cup clash is due to take place on Tuesday, October 26 with kick-off set for 7:45pm.
The fourth-round fixture will be played at Stamford Bridge, London.
talkSPORT will have live coverage of the game from 7:30pm with commentary coming from Joe Shennan and ex-England defender Danny Mills.
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Chelsea vs Southampton: Team news
The Blues have been handed a boost with the news that N’Golo Kante will be fit to return against the Saints.
The Frenchman missed the 7-0 rout over Norwich with muscle tightness but the club revealed his absence was just a precaution.
There is less positive news on Romelu Lukaku and Timo Werner, who are both not ready to return after suffering injuries against Malmo last week.
Christian Pulisic also remains a little away from his own comeback with this cup tie set to come too soon for the American.
Southampton meanwhile will be without Armando Broja – who scored against Burnley – as he is unable to play against his parent club Chelsea.
Ward-Prowse is still suspended from the ban he picked up the last time he faced the Blues and Jack Stephens is again missing due to a knee injury.
Chelsea vs Southampton: What has been said?
Tuchel has already dropped a hint that Callum Hudson-Odoi will feature against Southampton this week.
“He had a good game against Malmo, another good game today,” Tuchel said during his post-match press conference.
“There are still things to improve and work on, but it’s on him.
“It’s like I said before the game, he has to show he has to produce performances like this consistently and it’s time to show. Next performance is on Tuesday.”