England rugby chiefs announced on Tuesday that Tonga would kick-start their November Test programme at Twickenham.
Eddie Jones's men will face the Pacific Islanders on 6 November, before matches against Australia and world champions South Africa.
England last faced Tonga at the 2019 Rugby World Cup, winning 35-3 in the group stages.
"This match will continue our rivalry from the World Cup, where we had a good, tough game against them," said Jones.
"They produce a lot of good players and play physical, exciting rugby."
England finished this year's Six Nations in fifth place, but swept aside the United States and Canada earlier this month.
"With the young squad we had in July, the 13 players who joined up with the [British and Irish] Lions and the others who have spent the summer regenerating, we know that it will be a strong, competitive group of players this autumn," Jones said.
Tonga have been confirmed as our first opponents in our autumn fixtures at @Twickenhamstad ???
— England Rugby (@EnglandRugby) July 20, 2021
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