Donald Trump's children and their partners, (L-R) Kimberly Guilfoyle, Donald Trump Jr., Jared Kushner, Eric Trump, Ivanka Trump, Lara Trump, Michael Boulos and Tiffany Trump walk onto the White House North Portico following the funeral of Robert Trump on August 21, 2020 in Washington, DC.

Donald Trump's children would likely flip on their father Donald if they face criminal charges, the former US President's niece Mary has suggested.

She told MSNBC on Thursday that Ivanka, Eric, and Trump Jr. would be unlikely to show the same sort of loyalty to their father during a criminal case, as Trump's long-serving chief financial officer Alan Weisselberg has.

Weisselberg was this week served with multiple criminal charges after he refused to co-operate with officials investigating the former president's financial arrangements.

Weisselberg's 25-page indictment said that other executives also benefited from the scheme, raising the prospect that Donald Trump's children could be next to face charges.

"I think [Donald Jr., Ivanka, and Eric] should be quite anxious right now," she told MSNBC's Rachel Maddow on Thursday.

Mary Trump told the channel that while her uncle will "expect the same kind and level of loyalty as he expects from Alan," it would likely not be forthcoming.

"I think [Donald] would be surprised to learn that I don't believe my cousins would exercise that kind of loyalty towards him because his relationship with them and their relationship with him is entirely transactional and conditional.

"They're not going to risk anything for him just as he wouldn't risk anything for them," she said.

Mary Trump in June told CNN that she believed Trump would never sacrifice himself for his children if he faced legal peril.

"What would it mean to Donald Trump if they came after his kids? Would that change his disposition, do you think? Would he take one for his kids?" CNN's Chris Cuomo asked her.

"No, he wouldn't," she replied.

Weisselberg and the Trump Organisation pleaded not guilty to the charges laid against them by Manhattan District Attorney Cyrus Vance Jr. and New York Attorney General Letitia James, who worked together to bring the charges, Insider's Sonam Sheth and Jacob Shamsian reported.

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