Kourtney Kardashian has said ex-boyfriend Scott Disick's substance abuse issues were a "deal-breaker" for their relationship.
The reality star made the claim in a teaser for a reunion show that will air after the final episode of Keeping Up With The Kardashians.
The series, which became a pop culture juggernaut and brought global fame for the family, will come to an end this week after 14 years and 20 seasons.
The Kardashian-Jenners sat down with US TV host Andy Cohen for what has been billed as a nothing-off-limits discussion about their lives.
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The ultimate guide to Khloe Kardashian's style evolution Close
Khloe Kardashian in 2008, 2011 and 2015
July 2007: Khloe Kardashian and Kim Kardashian attends the Ashley Paige swimwear fashion show during "Mercedes Benz Fashion Week: Miami Swim"
October 2007: Actresss Kim Kardashian (L) and sister Khloe Kardashian arrives at the premiere of "Somebody Help Me" at the Grauman's Chinese Theatre
October 2007: (L-R) Kourtney, Kim, and Khloe Kardashian arrive at Kim's Birthday Party at Les Deux
March 2008: Television personality Khloe Kardashian attends the season two launch of "Keeping Up With The Kardashians"
March 2008: Khloe Kardashian attends the Perez Hilton's 30th Birthday Celebration at the Beverly Wilshire Hotel
April 2008: TV personality Kim Kardashian and Khloe Kardashian arrive at the National Lampoon Premiere of "One, Two, Many"
April 2008: TV personalities Kim and Khloe Kardashian pose backstage in the Awards Room at the MTV Australia Awards 2008 at the Australian Technology Park
April 2008: TV Personality Khloe Kardashian arrives at the Girls Gone Wild Magazine Launch party held at Area Nightclub
July 2008: TV Personality Khloe Kardashian attends the 2nd Annual Celebrity Bowling Night held by Matt Leinard
August 2008: TV personality Khloe Kardashian arrives at the premiere of Disney Channel's "The Cheetah Girls One World" held at the El Capitan Theater
September 2008: TV personality and designer Khloe Kardashian walks the runway at the Dash & Smooch Spring 2009 fashion show during Mercedes-Benz Fashion Week
December 2008: TV personality Khloe Kardashian unveils her PETA "Fur? I'd Rather Go Naked" billboard
January 2009: Khloe an Kourtney Kardashian attend DIRECTV's 3rd Annual Celebrity Beach Bowl
February 2009: Khloe Kardashian and Kim Kardashian pose at Payless at Alice + Olivia Fall 2009 show during Mercedes-Benz Fashion Week
February 2009: Khloe Kardashian attends the Badgley Mischka Fall 2009 fashion show during Mercedes-Benz Fashion Week
July 2009: TV personality Khloe Kardashian arrives at the White Party hosted by Sean "Diddy" Combs and Ashton Kutcher
Ctober 2009: TV Personality Khloe Kardashian arrives at the Famous Cupcakes Launch Party
April 2010: Khloe Kardashian poses for a picture at the Beach Bunny Swimwear's grand opening party
April 2010: Television personality Khloe Kardashian arrives at the Wet Republic pool at the MGM Grand Hotel/Casino to celebrate her sister Kourtney Kardashian's birthday
May 2010: TV personality Khloe Kardashian arrives at the E! 20th anniversary party celebrating two decades of pop culture held at The London Hotel.
April 2010: TV Personality Khloe Kardashian joins The Declaration of Real Talk campaign at the Flatiron District South Pedestrian Plaza
October 2010: Khloe Kardashian attends "The Spin Crowd" Season Finale Party
November 2010: Khloe Kardashian arrives at the Los Angeles Premiere of "Burlesque" at the Grauman's Chinese Theatre
January 2011: (L-R) TV personalities Kourtney Kardashian, Khloe Kardashian, and Kim Kardashian pose with the Favorite TV Guilty Pleasure Award in the press room during the 2011 People's Choice Awards at Nokia Theatre L.A. Live
January 2011: Khloe Kardashian backstage at the 16th annual Critics' Choice Movie Awards at the Hollywood Palladium
January 2011: TV personality Khloe Kardashian, winner of the Favorite TV Guilty Pleasure award poses for a portrait during the 2011 People's Choice Awards
February 2011: Khloe Kardashian Odom attends at the 2011 BBVA NBA All-Star Celebrity Game at the Los Angeles Convention Center
June 2011: Khloe Kardashian arrives for the "Goodbye cellulite, hello bikini" poolside party held at The NIVEA and Shay Todd Summer Chateau
November 2011: Khloe Kardashian and Kourtney Kardashian promote "Dollhouse" at the Barnes & Noble, 5th Avenue
November 2011: Kim Kardashian and Khloe Kardashian Odom attend a promotion for the Kardashian Kollection Handbag range at the David Jones Elizabeth Street Store
December 2011: Khloe Kardashian attends the 2011 Z100 & Coca-Cola All Access lounge at Z100's Jingle Ball 2011 pre-show at Hammerstein Ballroom
September 2012: Khloe Kardashian Odom attends the MDA Show of Strength held at CBS Television City
September 2012: TV personality Khloe Kardashian celebrates the 1 year anniversary of the Kardashian Kollection at Sears
December 2012: Khloé Kardashian Odom arrives at Fox's "The X Factor" Season Finale - Night 2 at CBS Television City
December 2012: Television personality Khloe Kardashian Odom arrives at Fox's "The X Factor" Season Finale Night 1
September 2013: TV personality Khloe Kardashian attends the iHeartRadio Music Festival at the MGM Grand Garden Arena
October 2013: Television personalities Khloe Kardashian (L) and Kourtney Kardashian arrive at the Tao Nightclub at The Venetian Las Vegas
November 2013: Khloe Kardashian attends the launch party for the Kardashian Kollection for Lipsy at Natural History Museum
November 2013: Khloe Kardashian arrives at the Kardashian Kollection cocktail party at the Park Hyatt Guest House
December 2013: TV personality Khloe Kardashian arrives at The Hollywood Reporter's 22nd Annual Women In Entertainment Breakfast at Beverly Hills Hotel
February 2014: Khloe Kardashian arrives at Generation NXT Charity Benefit at 1OAK
March 2014: TV personality Khloe Kardashian attends the 22nd Annual Elton John AIDS Foundation's Oscar Viewing Party
November 2014: (L-R) TV personalities Kendall Jenner, Khloe Kardashian and Kylie Jenner attend the 2014 American Music Awards
June 2014: Television personality Khloe Kardashian (L) and rapper French Montana arrive at the Tao Nightclub
December 2014: Khloe Kardashian attends The Hollywood Reporter's 23rd Annual Women In Entertainment Breakfast
February 2015: TV personality Khloe Kardashian attends GQ and Giorgio Armani Grammys After Party at Hollywood Athletic Club
April 2015: TV personality Khloe Kardashian attends Opening Ceremony and Calvin Klein Jeans' celebration launch of the #mycalvins Denim Series with special guest Kendall Jenner at Chateau Marmont
April 2015: Khloe Kardashian appears At ULTA Beauty's West Hills Store To Promote Kardashian Beauty Hair Care And Styling Line
April 2015: US reality TV star Kim Kardashian (2ndR) and her sister Khloe (2ndL) pose for pictures at a park in Yerevan
May 2015: Khloe Kardashian (L) and Kylie Jenner attend the 2015 NBCUniversal Cable Entertainment Upfront
July 2015: Actress Rumer Willis (L) and television personality Khloe Kardashian celebrate Independence Day at Encore Beach Club at Wynn Las Vegas
November 2015: Khloe Kardashian signs and discusses her new book "Strong Looks Better Naked" at Barnes & Noble at The Grove
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In the trailer, Kourtney, 42, is asked about her relationship with Disick - the father of her three children - and if it would have survived if it had not been so exposed to the public eye.
"I think the substance abuse was a deal-breaker," Kourtney says, before Disick, 38, admits: "I was pretty irresponsible."
Cohen then asks Disick about his feelings on Kourtney's relationship with Blink-182 drummer Travis Barker.
"So do Kourtney and Travis have your blessing?" Cohen says.
Kim Kardashian West, the star of the family's TV show who built a global brand from its success, also features in the reunion trailer.
She discusses a mystery moment between her and her mother Kris Jenner.
She says: "What people don't know is you said to me, 'I'm gonna put you in a car, no one will find you - just leave.'"
Jenner, 65, adds: "And I'll take care of it."
Kardashian West later says she "absolutely" owes an unnamed man an apology.
The two-part reunion, due to air in the US later this month, will also explore the cheating scandal between Khloe Kardashian and basketball star Tristan Thompson, as well as Jenner's relationship with former partner Caitlyn Jenner.
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The ultimate guide to Khloe Kardashian's style evolution Close
Khloe Kardashian in 2008, 2011 and 2015
July 2007: Khloe Kardashian and Kim Kardashian attends the Ashley Paige swimwear fashion show during "Mercedes Benz Fashion Week: Miami Swim"
October 2007: Actresss Kim Kardashian (L) and sister Khloe Kardashian arrives at the premiere of "Somebody Help Me" at the Grauman's Chinese Theatre
October 2007: (L-R) Kourtney, Kim, and Khloe Kardashian arrive at Kim's Birthday Party at Les Deux
March 2008: Television personality Khloe Kardashian attends the season two launch of "Keeping Up With The Kardashians"
March 2008: Khloe Kardashian attends the Perez Hilton's 30th Birthday Celebration at the Beverly Wilshire Hotel
April 2008: TV personality Kim Kardashian and Khloe Kardashian arrive at the National Lampoon Premiere of "One, Two, Many"
April 2008: TV personalities Kim and Khloe Kardashian pose backstage in the Awards Room at the MTV Australia Awards 2008 at the Australian Technology Park
April 2008: TV Personality Khloe Kardashian arrives at the Girls Gone Wild Magazine Launch party held at Area Nightclub
July 2008: TV Personality Khloe Kardashian attends the 2nd Annual Celebrity Bowling Night held by Matt Leinard
August 2008: TV personality Khloe Kardashian arrives at the premiere of Disney Channel's "The Cheetah Girls One World" held at the El Capitan Theater
September 2008: TV personality and designer Khloe Kardashian walks the runway at the Dash & Smooch Spring 2009 fashion show during Mercedes-Benz Fashion Week
December 2008: TV personality Khloe Kardashian unveils her PETA "Fur? I'd Rather Go Naked" billboard
January 2009: Khloe an Kourtney Kardashian attend DIRECTV's 3rd Annual Celebrity Beach Bowl
February 2009: Khloe Kardashian and Kim Kardashian pose at Payless at Alice + Olivia Fall 2009 show during Mercedes-Benz Fashion Week
February 2009: Khloe Kardashian attends the Badgley Mischka Fall 2009 fashion show during Mercedes-Benz Fashion Week
July 2009: TV personality Khloe Kardashian arrives at the White Party hosted by Sean "Diddy" Combs and Ashton Kutcher
Ctober 2009: TV Personality Khloe Kardashian arrives at the Famous Cupcakes Launch Party
April 2010: Khloe Kardashian poses for a picture at the Beach Bunny Swimwear's grand opening party
April 2010: Television personality Khloe Kardashian arrives at the Wet Republic pool at the MGM Grand Hotel/Casino to celebrate her sister Kourtney Kardashian's birthday
May 2010: TV personality Khloe Kardashian arrives at the E! 20th anniversary party celebrating two decades of pop culture held at The London Hotel.
April 2010: TV Personality Khloe Kardashian joins The Declaration of Real Talk campaign at the Flatiron District South Pedestrian Plaza
October 2010: Khloe Kardashian attends "The Spin Crowd" Season Finale Party
November 2010: Khloe Kardashian arrives at the Los Angeles Premiere of "Burlesque" at the Grauman's Chinese Theatre
January 2011: (L-R) TV personalities Kourtney Kardashian, Khloe Kardashian, and Kim Kardashian pose with the Favorite TV Guilty Pleasure Award in the press room during the 2011 People's Choice Awards at Nokia Theatre L.A. Live
January 2011: Khloe Kardashian backstage at the 16th annual Critics' Choice Movie Awards at the Hollywood Palladium
January 2011: TV personality Khloe Kardashian, winner of the Favorite TV Guilty Pleasure award poses for a portrait during the 2011 People's Choice Awards
February 2011: Khloe Kardashian Odom attends at the 2011 BBVA NBA All-Star Celebrity Game at the Los Angeles Convention Center
June 2011: Khloe Kardashian arrives for the "Goodbye cellulite, hello bikini" poolside party held at The NIVEA and Shay Todd Summer Chateau
November 2011: Khloe Kardashian and Kourtney Kardashian promote "Dollhouse" at the Barnes & Noble, 5th Avenue
November 2011: Kim Kardashian and Khloe Kardashian Odom attend a promotion for the Kardashian Kollection Handbag range at the David Jones Elizabeth Street Store
December 2011: Khloe Kardashian attends the 2011 Z100 & Coca-Cola All Access lounge at Z100's Jingle Ball 2011 pre-show at Hammerstein Ballroom
September 2012: Khloe Kardashian Odom attends the MDA Show of Strength held at CBS Television City
September 2012: TV personality Khloe Kardashian celebrates the 1 year anniversary of the Kardashian Kollection at Sears
December 2012: Khloé Kardashian Odom arrives at Fox's "The X Factor" Season Finale - Night 2 at CBS Television City
December 2012: Television personality Khloe Kardashian Odom arrives at Fox's "The X Factor" Season Finale Night 1
September 2013: TV personality Khloe Kardashian attends the iHeartRadio Music Festival at the MGM Grand Garden Arena
October 2013: Television personalities Khloe Kardashian (L) and Kourtney Kardashian arrive at the Tao Nightclub at The Venetian Las Vegas
November 2013: Khloe Kardashian attends the launch party for the Kardashian Kollection for Lipsy at Natural History Museum
November 2013: Khloe Kardashian arrives at the Kardashian Kollection cocktail party at the Park Hyatt Guest House
December 2013: TV personality Khloe Kardashian arrives at The Hollywood Reporter's 22nd Annual Women In Entertainment Breakfast at Beverly Hills Hotel
February 2014: Khloe Kardashian arrives at Generation NXT Charity Benefit at 1OAK
March 2014: TV personality Khloe Kardashian attends the 22nd Annual Elton John AIDS Foundation's Oscar Viewing Party
November 2014: (L-R) TV personalities Kendall Jenner, Khloe Kardashian and Kylie Jenner attend the 2014 American Music Awards
June 2014: Television personality Khloe Kardashian (L) and rapper French Montana arrive at the Tao Nightclub
December 2014: Khloe Kardashian attends The Hollywood Reporter's 23rd Annual Women In Entertainment Breakfast
February 2015: TV personality Khloe Kardashian attends GQ and Giorgio Armani Grammys After Party at Hollywood Athletic Club
April 2015: TV personality Khloe Kardashian attends Opening Ceremony and Calvin Klein Jeans' celebration launch of the #mycalvins Denim Series with special guest Kendall Jenner at Chateau Marmont
April 2015: Khloe Kardashian appears At ULTA Beauty's West Hills Store To Promote Kardashian Beauty Hair Care And Styling Line
April 2015: US reality TV star Kim Kardashian (2ndR) and her sister Khloe (2ndL) pose for pictures at a park in Yerevan
May 2015: Khloe Kardashian (L) and Kylie Jenner attend the 2015 NBCUniversal Cable Entertainment Upfront
July 2015: Actress Rumer Willis (L) and television personality Khloe Kardashian celebrate Independence Day at Encore Beach Club at Wynn Las Vegas
November 2015: Khloe Kardashian signs and discusses her new book "Strong Looks Better Naked" at Barnes & Noble at The Grove
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