Research reveals: Our immune system works differently in day and night

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It is generally believed that the human immune system works the same way all the time. The assumption was that it did not matter whether the infection occurred during the day or at night. However, research has now shown that our immune system deals with infection differently during the day and night. Even at what time of the day we get the vaccine, it also has an effect on immunity. Experts consider the body's biological clock responsible for these.


biological clock adjusts the body

According to researcher Anne Cartis of the RCSI University of Health and Sciences in Dublin, our biological clock has evolved over millions of years. It automatically adjusts our work and behavior by understanding the time of day and night. The biological clock does this by creating a 24-hour rhythm (circadian rhythm) for cellular activities. For example, at night, the body clock ensures the production of the hormone melatonin in the body. This chemical exhausts the body and we start getting the signal to sleep.

The vaccine was more effective in the morning

There is also ample evidence that the timing of day and night is important in developing immunity against the pathogens of certain diseases. In 2016, there was research on 250 adults aged 65 years and above. It was found that people who got the influenza vaccine between 9 am and 11 am, got more antibodies in their body than those who took the dose later in the afternoon. Similarly, until recently, young people aged about 25 who received the BBC vaccine in the morning were found to have higher immunity than those who took the vaccine between 12 noon and 1 a.m.

...then what in Corona?

After such research, questions about the timing of corona vaccination are bound to arise. But the answer is yet to be found. Experts agree that given the urgency and the impact of corona vaccines, we should get vaccinated at any time of the day.

The time of taking the medicine also decides its effect.

Some research has shown that the effectiveness of the drug also depends on the time taken. For example, cholesterol is formed in the body while sleeping. In such a situation, it is more beneficial to take cholesterol-lowering medicine just before sleeping. The study also found that the time of day affects the function of certain types of immune cells.

This is how the body is better protected

Broadly speaking, during the day our immunity goes into the tissues and then spreads throughout the body at night. According to experts, this circadian rhythm of immune cells may have evolved so that during times of high risk of infection, cells move around the body and stay in our lymph nodes. Here she creates a memory of activities that happened during the day, including the transition. This ensures the cells are able to respond better the next time they are faced with an infection.

Samples of 28 elephants taken for Kovid test in Tamil Nadu

Samples of 28 elephants were taken for the COVID-19 test at a camp in Tamil Nadu's Udhagamandalam district on Tuesday. A zoo in Chennai is being investigated after a lioness died of Kovid-19 a few days ago and nine others were infected.

According to forest department sources, Forest Minister K Ramachandran has ordered to take samples of all the elephants and send them to the Indian Veterinary Research Institute at Izzat Nagar, Bareilly in Uttar Pradesh for testing. After that, samples of all 28 elephants were taken till noon at the Mudumalai camp nearby here, he said.