The German star will take on world No. 49 Kei Nishikori of Japan, who made it to the pre-quarterfinals after qualifier Henri Laaksonen of Switzerland was forced to retire due to a thigh injury while trailing 5-7 in the first set. 

This is the seventh time Nishikori, who reached a career-high ranking of No. 4 in 2015, has entered the fourth round in Paris. 

Argentina's world No. 51 Federico Delbonis broke a two-match losing streak against Italian 29th ranked player Fabio Fognini to make his maiden entry into a Grand Slam fourth round. 

In a rain-interrupted match, Delbonis capitalised on his solid first serve to record a 6-4, 6-1, 6-3 win over Fognini in two hours and six minutes. 

Debonis will take on Spain's Alejandro Davidovich Fokina who won a marathon five-setter against Norwegian 15th seed Casper Ruud 7-6(3), 2-6, 7-6(6), 0-6, 7-5 to secure a pre-quarterfinal berth. 

Fokina, who had also reached the 2020 US Open fourth round, saved four break points in the final game to close out one of the biggest wins of his career after a contest lasting four hours and 35 minutes. 

Earlier, 24-year-old Zverev saved three set points at 4-5 in the second set and then won nine of the next 11 games to get past Djere. Zverev struck 31 winners and converted seven of 10 break points for victory.