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Coronavirus News LIVE Updates: Our Vaccine Highly Effective on New Covid Variant, Pfizer Tells Govt; India's Active Cases Drop Further

Coronavirus News LIVE Updates: Pfizer, which is ready to offer 5 crore doses to India between July and October this year, has sought certain relaxations including indemnification.

News18.com | May 27, 2021, 14:08 IST

Coronavirus News LIVE Updates: Seeking a fast-track approval for its COVID-19 vaccine, US major Pfizer has told Indian authorities that its jab has shown “high effectiveness” against the SARS-CoV-2 variant prevalent in India, while it is suitable for everyone aged 12 years or above and can be stored for a month at 2-8 degrees, sources said on Wednesday. Pfizer, which is ready to offer 5 crore doses to India between July and October this year and has sought certain relaxations including indemnification, has held a series of interactions with the Indian government authorities recently, including one this week, during which it shared the most recent data points regarding efficacy trials and approvals for its vaccine in various countries and by the World Health Organisation (WHO).

“The current situation in India, and across the world, is not business as usual’ and we must not respond to it with processes as usual too,” a source quoted Pfizer as having communicated to the Indian government. Another source privy to the discussions said that following recent meetings between the Indian government and Pfizer’s Chairman and CEO Albert Bourla, they have agreed to jointly work on three key issues to accelerate approval for the company’s COVID-19 vaccine in India, namely procurement through a central government pathway; indemnity and liability; and the regulatory requirement for post-approval bridging studies.

While India has administered over 20 crore doses so far since the launch of its vaccination drive in mid-January, it is still a long way to reach the vaccination for the entire population, more so in the backdrop of many states having flagged shortage of vaccines and the gap between supply and requirement widening amid the deadly second wave. India is currently using mainly two ‘made-in India’ jabs Covishield manufactured by the Serum Institute and Covaxin of Bharat Biotech and Russian-made Sputnik V at a smaller scale to inoculate its population, all of which are approved only for those aged 18 years and above.

May 27, 2021 14:08 (IST)

Govt, Pfizer Working Together for Earliest Possible Import of Vaccine: VK Paul | As soon as Pfizer indicated vaccine availability, the central government and the company started working together for the earliest possible import of the vaccine, NITI Aayog member VK Paul said on Thursday. Paul, in a statement on 'Myth and Facts on India's Vaccination Process' pointed out that vaccines are in limited supply globally, and companies have their own priorities, gameplans and compulsions in allocating finite stocks.

May 27, 2021 13:48 (IST)
HC Allows Duty Free Import of Drug to Treat Black Fungus Till Centre Decides on Waiver | The Delhi High Court Thursday allowed duty free import of Amphotericin B, used for treating black fungus patients, primarily those affected by it after recovering from COVID19, on furnishing of a bond by the importers till the Centre takes a final decision on waiving the customs duty on it.
 
The high court said the medicine is required to save lives of thousands of people suffering from Mucormycosis and the central government shall seriously consider waiver of customs duty till the drug is in short supply in India.
May 27, 2021 13:30 (IST)
Delhi Hospital Reports 'First-ever' White Fungus Case Causing Severe Damage to Entire Intestine | Delhi's Sir Ganga Ram Hospital (SGRH) has come across a firstofitskind case of white fungus which causes multiple perforations throughout the intestine in a COVID19 patient, doctors said on Thursday. White fungus (Candida) causing multifocal perforations in the food pipe, small bowel and large bowel in COVID19 infection has not been reported in literature to the best of our knowledge, Dr Anil Arora, Chairman of the Institute of Liver, Gastroenterology and Pancreaticobiliary Sciences at the hospital, said.
May 27, 2021 12:53 (IST)
Puducherry Adds 1,137 Fresh COVID-19 Cases, Overall Tally Crosses One Lakh Mark | The union territory of Puducherry logged 1,137 new coronavirus cases during the last 24 hours taking the overall tally to 1,00,677, a senior official of the Health Department said on Thursday. The new cases were identified at the end of the examination of 9,473 samples, projecting a test positivity rate at 12 per cent, Director of Department of Health and Family Welfare Services S Mohan Kumar said.
May 27, 2021 12:47 (IST)

COVID Second Wave Triggers Raft of Growth Forecast Revisions: RBI Annual Report | Reserve Bank of India on Thursday said that the second wave of COVID-19 pandemic has triggered revision of growth projections for the current financial year with consensus gravitating towards its earlier forecast of 10.5 per cent. The central bank, in its annual report for 2020-2021, further said that previous year has left a scar on the economy and "in the midst of the second wave, as 2021-22 commences, pervasive despair is being lifted by cautious optimism built up by vaccination drives."

May 27, 2021 11:35 (IST)

With efforts of Union Minister Nitin Gadkari, Genetic Life Sciences, Wardha has manufactured Amphotericin B Emulsion injections for treating Mucormycosis. It was being produced by only one company so far. Distribution to begin from Monday at Rs 1200 each: Office of the Union Minister

May 27, 2021 11:29 (IST)

No Vaccine, No Salary: Chhattisgarh Tribal Dept Officer Warns Staff | A tribal welfare department officer in a Chhattisgarh district has issued an order asking its staff members to get vaccinated against COVID-19, failing which their salaries for the next month will be withheld. A copy of the order, issued by the assistant commissioner K S Masram in Gaurela-Pendra-Marwahi district on May 21, went viral on social media where some people expressed displeasure over the 'diktat'.

May 27, 2021 11:05 (IST)

B.1.617 COVID19 Variant, First Detected in India, Now Found in 53 Countries: WHO | The B.1.617 COVID-19 variant, first detected in India, has now been found in 53 countries, according to the WHO, which noted that India recorded a 23 per cent decrease in the number of new cases in the last seven days but they were still the highest in the world. The World Health Organisation's COVID-19 Weekly Epidemiological Update, published May 25, said that over the past week, the number of new cases and deaths continued to decrease globally, with over 4.1 million new cases and 84,000 new deaths reported, a 14 per cent and 2 per cent decrease respectively compared to the previous week.

May 27, 2021 10:42 (IST)

Government of India is doing everything possible to increase availability of Liposomal Amphotericin B injections to deal with Mucormycosis. To augment production, Government of India has given licenses to 5 more companies that can make this drug, sources tell ANI. 

PM had instructed officials to get this drug from anywhere it is available in the world. Indian missions across the world have been involved in securing supplies of this drug. It has been achieved with help of Gilead Sciences in USA: GoI sources

Gilead Sciences is working on expediting the supply of AmBisome to India through Mylan. More than 121,000 vials have so far reached India. Another 85,000 vials are on the way. The company will supply 1 million doses of AmBisome to India through Mylan: GoI sources

May 27, 2021 10:32 (IST)

Zydus Cadila says it has sought the approval of the Drugs Controller General of Inda (DCGI) to undertake clinical trials for monoclonal antibodies cocktail that can neutralise COVID-19 infection.

May 27, 2021 10:10 (IST)

Marriages Held Secretly, Flouting Covid Lockdown, to be Declared Illegal in Madhya Pradesh | To curb cases of weddings being conducted discretely, flouting Covid-19 lockdown regulations, few district administrations in Madhya Pradesh have decided to declare these marriages null and void. The couples will also not be issued marriage certificates.

The Shivraj Singh Chouhan-led state government had banned weddings in May in the wake of rapid spread of Covid-19 cases, but marriages continued to take place. Read the full story here.

May 27, 2021 09:43 (IST)

Today's Covid-19 Data Update:

India reports 2,11,298 new COVID-19 cases, 2,83,135 discharges and 3,847 deaths in last 24 hrs, as per Health Ministry.

Total cases: 2,73,69,093
Total discharges: 2,46,33,951
Death toll: 3,15,235    
Active cases: 24,19,907
Total vaccination: 20,26,95,874

May 27, 2021 09:42 (IST)

Probe Ordered into Vaccine Mix-up in UP Village | After initially denying that about 20 residents of a village in Uttar Pradesh's Siddhartha Nagar district were administered a different vaccine brand for the second dose, Chief Medical Officer (CMO) Sandeep Chaudhary said that an inquiry has been ordered into the incident.

He said stern action would be taken against those responsible for the mix-up.

Health workers in the district had administered the Covaxin to 20 villagers who had been given Covishield in the first dose.

May 27, 2021 08:47 (IST)

Karnataka Offers Sops to Set up Oxygen Production Plants | Reeling under shortage of medical oxygen due to growing demand amid the pandemic's second wave, Karnataka on Wednesday offered incentives to industry to set up the gas production plants in the state.

"We are offering incentives to industrialists for setting up production plants to make the state self-sufficient in medical oxygen," Industries Minister Jagadish Shettar said in a statement.

May 27, 2021 08:14 (IST)

Volunteers Come Forward to Give Covid Victims Dignified Farewell in Rajasthan | Amid the Covid gloom in Rajasthan, volunteers have come forward to give a dignified farewell to Covid victims by performing their last rites, even as heart-wrenching scenes continue to pour in from different cremation grounds from across the desert state.

These are the victims whose relatives are either hospitalised, or have fallen prey to the dreaded infection.

May 27, 2021 08:04 (IST)

Biden Asks Intel Community to Redouble Efforts to Trace Origins of COVID-19 | US President Joe Biden asked his intelligence agencies on Wednesday to redouble their efforts to find out the origins of the deadly COVID-19 pandemic that has had devastating consequences in countries across the globe. "I have now asked the Intelligence Community to redouble their efforts to collect and analyze information that could bring us closer to a definitive conclusion, and to report back to me in 90 days," Biden said in a statement.

As part of that report, the president said he has asked for areas of further inquiry that may be required, including specific questions for China. "I have also asked that this effort include work by our National Labs and other agencies of our government to augment the Intelligence Community's efforts. And I have asked the Intelligence Community to keep Congress fully apprised of its work," he said.

May 27, 2021 07:27 (IST)

Assam Reports 5,699 Fresh COVID-19 Cases, 90 Deaths | Assam reported 90 COVID-19 fatalities and 5,699 fresh infections on Wednesday, raising the death toll and the caseload to 3,005 and 3,86,870, respectively, a health bulletin said. The northeastern state now has 52,884 active cases, while 3,29,634 people have so far recovered from the disease, including 6,266 since Tuesday, it said.

May 27, 2021 07:25 (IST)

Bengal Reports Lower Fresh COVID-19 Cases at 16,225, Toll | West Bengal continued to record a decline in single-day spike of COVID-19 cases on Wednesday, logging 16,225 fresh infections, raising the tally to 13,18,203, a health department bulletin said. The death toll mounted to 14,827 after 153 more fatalities were reported from different parts of the state, it said.

West Bengal now has 1,23,377 active cases, while 11,79,999 patients have recovered from the disease, including 19,071 since Tuesday. A total of 1,21,21,940 samples have so far been tested for COVID-19, taking into account 63,976 clinical examinations in the last 24 hours, the bulletin said.

May 27, 2021 07:21 (IST)

Octogenarian Covid Patient Who Received Monoclonal Antibody Therapy, Back Home: Hospital | An 84-year-old Covid positive man who was given monoclonal antibody therapy in Gurgaon, which is said to reduce the chance of hospitalisation by 70 per cent in patients with mild to moderate symptoms, is back to his home, hospital authorities said on Wednesday. Mohabbat Singh was administered a cocktail of Casirivimab and Imdevimab at the Medanta Hospital as part of the "single dose infusion-based treatment" on Tuesday and then kept under observation.

"After being kept under observation, he was sent home yesterday only," a spokesperson of the hospital said. An official of the hospital claimed it was Delhi-NCR's first case of monoclonal antibody therapy for a Covid patient. Suffering from COVID-19, Singh is the first patient to receive monoclonal antibody therapy at Medanta, Gurgaon, he said.

May 27, 2021 07:19 (IST)

Part-vaccinated and Part-neglected World is Not Going to Be Safe: Jaishankar | A part-vaccinated and part-neglected world is not going to be safe and if large countries pursue their national interest, disregarding everything else, the world is going to have some "big problems", External Affairs Minister S Jaishankar said on Wednesday, underling that "our sense of national security" has widened as a consequence of the COVID-19 pandemic. With the COVID-19 pandemic bearing heavily on everyone's minds, he said there are questions about vaccine accessibility and affordability.

May 27, 2021 07:18 (IST)

Pfizer Tells Centre Its COVID-19 Vaccine Suitable for All Aged 12 and Above | As India is facing an accute shortage of vaccine at home, Pfizer has informed the Centre, during a series of interactions, that its COVID-19 vaccine is suitable for all aged 12 and above, and can be storied at 2-8 degrees for over a months, said ANI sources. They also discussed indemnity protection against liabilities before they bring vaccines to India, the news agency reported. 

May 27, 2021 07:11 (IST)

Delhi's Vaccine Stock Over for 45+ Age Group Left for 12 Days: Atishi | The Delhi government has exhausted its Covaxin stock for people over 45 years while that of Covishield will last only 12 days, AAP MLA Atishi said on Wednesday. So, this means that those awaiting their second dose of Covaxin in Delhi are in a situation wherein they may be wondering if their first dose will go to waste, she said.

Covaxin doses are administered at Centre-run hospitals like the All India Institute of Medical Sciences (AIIMS). For the 45 and above group, about 2.92 lakh doses of Covishield are in stock and this can be used for just 12 days of vaccination. The Covaxin stock, which was available at a diminished scale till recently, is already exhausted, Atishi said.

Coronavirus News LIVE Updates: Our Vaccine Highly Effective on New Covid Variant, Pfizer Tells Govt; India's Active Cases Drop Further
A medical worker waits for people who will receive a second dose of the Pfizer-BioNTech vaccine against COVID-19 in Belgrade, Serbia. (Reuters)

In its latest communication to the government, Pfizer has also thanked the Government of India to have agreed to its request for procurement through a central government pathway and to discuss “the Indemnity and Liability protection”. “The timely alignment and execution of the draft Heads of Terms will enable Pfizer to reserve the allocation of doses and pave the pathway for executing the Distribution and Supply Agreement,” the company told the government while seeking fast-tracking the regulatory pathway to help it supply “Pfizer’s COVID-19 vaccine as expeditiously as possible to India”.

Pfizer has said India should “rely on the 44 authorizations, including WHO approval, facilitate a EUA (Emergency Use Authorisation)/Restricted Use pathway for the Pfizer vaccine in India, and not seek a local PSA (Post Approval Commitment) study.” The company is, however, open to considering safety surveillance of the first 100 subjects after understanding the process to be followed. It has also stated that the Pfizer vaccine has undergone significant development over the last six months which includes improvement in storage conditions at 208 degrees for over one month (31 days) at the site of vaccination.

“Recent data points confirm the high effectiveness of BNT612b2 2-dose regimen against SARS-CoV-2 variants, and among individuals of Indian ethnicity,” Pfizer has said. Providing data, it said UK’s Public Health England (PHE) has reported high vaccine effectiveness (87.9 per cent) against the B.1.617.2 variant, most reported in India, in an observational study (concluded on May 22, 2021).

It further said 26 per cent of study participants overall were of “Indian or British Indian” ethnicity, and also included Bangladeshi (1.4 per cent), Pakistani (5.9 per cent) and any other Asian background (5.7 per cent), indicating that the observed vaccine effectiveness applies to these groups as well. Also, the data from Qatar’s nationwide immunization program demonstrated high vaccine effectiveness – 89 per cent against B.1.1.7 variant (first detected in the UK) and 75 per cent against B.1.351 variant (first detected in South Africa).

It said 24 per cent of study participants were of Indian nationality (more than 6,000), and others included Nepalese (6-12 per cent), Bangladeshi (4-11 per cent), Sri Lankan (3-4 per cent), Pakistani (4-6 per cent), indicating that the observed vaccine effectiveness applies to these groups as well. Pfizer has urged the Government of India to rely upon WHO’s testing pathways of reliance on testing certificates from country of origin instead of mandating local testing and batch release stating will also help fast track vaccine introduction and prevent vaccine wastage.

Pfizer has also shared the most recent data on BNT162b2 mRNA vaccine — the phase 3 clinical trial showing vaccine efficacy six months after the second dose from the pivotal registration trial, as also for variants in vitro neutralization, clinically efficacy data and real-world vaccine effectiveness against emerging variants of SARS-CoV-2. The data shared with Indian authorities also include “real-world evidence of BNT162b2 vaccine effectiveness and safety from national immunization programmes”. The shared datapoints include trials showing nearly 95 per cent effectiveness against COVID-19, 100 per cent efficacy against severe disease and also 100 per cent vaccine efficacy in 12-15-year-old adolescents.

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