More than 33 million people in the UK have received at least one dose of a coronavirus vaccine - part of the biggest inoculation programme the country has ever launched.

In a race against a faster-spreading variant of the virus, ministers have pinned their hopes for further easing of a third national lockdown on vaccinating as many adults as possible by summer.

But vaccine supply issues have made the rollout bumpy.

First vaccines are now being offered to people below the age of 50 after the UK government hit its target of offering a first jab to everyone in the top priority groups - all those over the age of 50, plus those in high-risk categories - before 15 April.

These priority groups account for 99% of coronavirus deaths so far.

Those considered most at risk - people aged 70 and over, care home residents, healthcare workers and people required to shield - were offered a jab by mid-February.

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The over-45s in England and Scotland and the over-40s in Wales and Northern Ireland have been asked to book appointments.

The government plans to vaccinate the rest of the adult population, another 21 million people, by the end of July.

People will be vaccinated in age order until all those over 20 have had a first dose.

More than 33 million people have had a first vaccine dose and over than 12 million have had a second.

The number of first doses administered each day is now averaging around 116,000 - a drop from an average of about 500,000 in mid-March - as the schedule of second doses kicks in.

An average of about 379,000 second doses are now being given a day.

Despite an expected dip in vaccine supply in April, the government says the country is still on track to offer a first dose to all adults by the end of July.

This will be helped by the rollout of a third approved vaccine, made by Moderna, which has joined the vaccines being distributed in the UK.

Those aged under 30 are to be offered the Moderna or Pfizer-BioNTech jabs as an alternative to the Oxford-AstraZeneca vaccine due to evidence linking it to rare blood clots.

The campaign to reach as many people as quickly as possible was boosted by a shift in policy in early January - to prioritise the first dose of a vaccine, with a second dose up to 12 weeks later, a bigger gap than originally planned.

The progress made in the UK so far means the country continues to be among those with the highest vaccination rates globally.

There continues to be some regional variation in the vaccine programme.

England, on average, has vaccinated 95% of those aged 50 and over, with the South West reaching 97% of people in that age group and London 87%.

In Scotland, 98% of over 50s have had at least one dose of the vaccine, while Wales has reached 92% and Northern Ireland 89%.

When looking at all those aged 18 and above, England, Scotland, Wales and Northern Ireland have all vaccinated more than half of adults with the first dose.

Second doses are also being rolled out. Wales has administered the second dose to 25% of adults, driven by the prioritisation of vaccines to those working in the health and care sectors.

There have also been disparities between ethnic groups and poorer and wealthier areas.

Analysis of NHS records by the OpenSAFELY group - a collaboration between Oxford University and the London School of Hygiene and Tropical Medicine - shows that black people were the least likely to have received a vaccine among six of the older age groups.

The study was based on more than 20 million patient records in England and covers people not living in care homes. Areas of London are under-represented in the data.

In addition, vaccine take-up in poorer areas is lower than in more affluent areas.

For example, 75% of those aged 50-54 in the poorest areas had been given a vaccine by 14 April, compared with 90% in the most affluent.

The UK is now receiving doses of three vaccines approved by the medicine regulator.

The Pfizer-BioNTech jab - the first to be given the green light in December - is being imported from Puurs, Belgium.

A second vaccine, from Oxford University and AstraZeneca, is being made at a number of sites in Britain. Further doses are expected to come from the Serum Institute of India and the Halix plant in the Dutch city of Leiden.

The third, from Moderna, is coming from sites in Switzerland and Spain, via Belgium.

The UK is also lined up to receive at least three further vaccines if they are approved for use.

A jab manufactured by US firm Novavax will be made in Stockton-on-Tees in north-east England, while another by French company Valneva will be made in Livingston, West Lothian, Scotland.

The third, produced in the Netherlands by Belgian firm Janssen, owned by Johnson & Johnson, should also be available later this year.

People will be vaccinated in three main ways, at:

The government has urged the public to "play their part" in supporting "the largest vaccination programme in British history", including helping people attend their appointments.

Some vaccine centres will close temporarily in April as supply shortages kick in, while others will stop taking bookings for first dose appointments.

The UK has ordered more than 400 million doses of seven of the most promising vaccines.

Three have so far been approved for use: Oxford-AstraZeneca; Pfizer-BioNTech; and Moderna.

The UK government has also announced an eighth deal with biopharmaceutical company CureVac to develop vaccines against future variants.

It has placed an initial order for 50 million doses to be delivered later this year - if they are required.

But there have been a number of challenges in what is called the vaccine "supply chain" - the logistics of how the jab gets from manufacturers to people.

Getting enough supplies, checking those supplies are up to scratch and transporting vaccines according to their requirements have all thrown up difficulties.

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