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(Bloomberg) -- The U.S. recorded 4 million vaccine doses on Friday, returning the pace of inoculations almost to the level before a post holiday lull, according to the Bloomberg Vaccine Tracker.Governor Gretchen Whitmer called for Michiganders to voluntarily suspend social activities for two weeks, and asked the federal government to prioritize additional vaccines to the state, to help slow the spread in the hottest Covid-19 spot in the U.S. Pfizer Inc. and its partner BioNTech SE said they would ask regulators in the U.S. and elsewhere to allow use of their Covid-19 vaccine in adolescents ages 12 to 15. A Johns Hopkins University’s professor said AstraZeneca Plc’s shots are still safe “overall” even as some countries limited its use, while the company that designed the vaccine is planning a U.S. IPO. Key Developments:Global Tracker: Cases pass 134.3 million; deaths 2.9 millionVaccine Tracker: More than 748 million shots given worldwideMichigan’s spread is putting pressure on the state even after speeding up vaccinationVaccine pace runs 2,400% faster in wealthiest countriesOntario businesses were dealt a huge blow as it entered a state of emergency this week CVS welcomes desperate vaccine hunters looking for second doseEurope finds some rare successes in its struggle to defeat CovidSubscribe to a daily update on the virus from Bloomberg’s Prognosis team here. Click CVID on the terminal for global data on cases and deaths.U.S. Vaccinations Climb (7:05 a.m. HK)The U.S. recorded 4 million vaccine doses on Friday, returning the pace of inoculations almost to the level before a post holiday lull, according to the Bloomberg Vaccine Tracker.It was the third straight day of increases, with the seven-day average now at 3.03 million doses a day. So far, 179 million doses have been administered. At this pace, it’s estimated to take another 3 months to cover 75% of the population.Brazil Health Agency Meet Russia, India Ambassadors (6:54 a.m. HK)Antonio Barra Torres, the head of Brazilian health regulator met with Russian Ambassador to Brazil Alexey Labetskiy to clarify pending issues for the approval of the Sputnik V vaccine. Torres addressed the requests for import and emergency use of Sputnik V, stressing the agency awaits the fulfillment of legal requirements to move ahead with the analysis.In a separate videoconference with the Indian Ambassador to Brazil Suresh Reddy, Torres discussed ways for the regulatory agencies of both countries to collaborate and improve the exchange of information regarding the Covaxin vaccine.Oxford-AstraZeneca Vaccine Designer Plans U.S. IPO (6:37 a.m. HK)A company founded by University of Oxford scientists who designed the vaccine co-developed with AstraZeneca will begin selling American depositary shares in the U.S.Vaccitech Plc, founded by Oxford professors Adrian Hill and Sarah Gilbert, wants to raise as much as $100 million by selling shares to investors, according to the filing Friday. In addition to vaccines against infectious disease, the company is aiming to develop treatments for hepatitis B virus, human papillomavirus and prostate cancer.U. of Kentucky Offers Student Vaccinations (5:47 p.m. NY)The University of Kentucky is inviting more than 21,000 admitted students -- those who have been offered enrollment this fall -- and their families to register for a vaccination.The school is offering vaccines at its football stadium, Kroger Field. Nearly 14,000 students have been vaccinated already, and more than 3,000 are in the process.Duke on Friday joined a group of universities that will require students to get a vaccine in order to return to campus in the fall. Other schools include Rutgers, Brown, Cornell and Northeastern.J&J Symptoms No ‘Reason for Concern’ (5:37 p.m. NY)The U.S. Centers for Disease Control is working with health departments in four states to evaluate symptoms experienced after Johnson & Johnson vaccinations but has “not found any reason for concern,” a spokeswoman said in a statement.“Many people don’t have any side effects after Covid-19 vaccines, but some people will have pain or swelling at the injection site or fever, chills, or a headache,” spokeswoman Kristen Nordlund said. “These typically don’t last long and are signs that your body is building protection.”She said the states are Colorado, North Carolina, Georgia and Iowa. The symptoms include “dizziness, light headedness, feeling faint, rapid breathing, and sweating.” She said the CDC “is aware of other instances of these symptoms occurring with the other Covid-19 vaccines.”Ireland Expands Quarantine List (5:13 p.m. NY)People traveling to Ireland from a host of countries including the U.S. and France will have to quarantine for 14 days from next week, the Irish health ministry said. From April 15, travelers from those countries will be met on arrival in Ireland and brought to a hotel for two weeks at their own expense. The quarantine can be shortened if a person tests negative after 10 days.Ireland already requires passengers arriving from more than 50 countries to stay in these hotels, while travelers from other nations are required to have a negative test within three days of travel and self quarantine when they arrive. Overall 16 countries including Canada and Belgium were added to the list Friday, while three including Israel will be removed.Colorado Hit by ‘Fourth Wave’ (5 p.m. NY)Colorado Governor Jared Polis said the state has been hit by a “fourth wave” of the coronavirus, sending hospitalizations to 404, the highest since Feb. 19. Most Covid-19 hospital patients are in the 18-50 age group, a development of “great alarm,” Polis said at a Friday news conference in Denver. Colorado has adequate hospital capacity to handle the new wave, he said.NYC Subways Reach Pandemic Record (4:16 p.m. NY)Subway ridership in New York City on Thursday topped 2 million for the first time since the beginning of the pandemic, the Metropolitan Transportation Authority said in a statement. Bus ridership reached the highest level since September.Subway ridership fell rapidly in March 2020, from more than 5 million rides a day during the workweek to less than half a million within a few weeks.Sugar Rallies on Reopening Optimism (4:08 p.m. NY)Sugar, arabica coffee and cotton prices are rallying as Covid-19 vaccinations advance, spurring bets that people will return to cafes and stores. A Bloomberg index tracking prices for the three crops is up more than 5% this week, the most since Feb. 19.A Goldman Sachs Group report projected bigger demand ahead. Sugar prices, which are leading the rally, have also been supported by bottlenecks that slowed exports from India.Astra Should Be in ‘Toolkit’: JHU (3:10 p.m. NY)AstraZeneca’s Covid-19 vaccine has a “communication problem” rather than a “science” problem, Lauren Sauer, Johns Hopkins University’s associate professor of Emergency Medicine, said in a Bloomberg Radio interview. The vaccine could help in areas where there’s community spread, particularly among the elderly.“This is just another tool in our toolkit and part of it is about the potential risk of these rare events,” Sauer said. “But we do know that it is overall safe and quite effective especially in our older population.”France Reaches Vaccine Record (2:23 p.m. NY)France administered a record 510,267 vaccine doses on Friday, bringing the total number of shots given since the inoculation campaign began to 14.1 million.The country is speeding up vaccinations after a sluggish start as it battles a resurgence of the virus. The government reported 41,243 new cases and 301 deaths in the past 24 hours.Germany Counts 42 Clot Cases After Astra Shot (2:17 p.m. NY)Germany’s Paul Ehrlich Institute said it has now counted 42 cases of a rare type of brain blood clot in people who were vaccinated with AstraZeneca’s shot.All but seven of the cases were in women aged 20 to 63, the drug safety oversight body said. Doctors also found low blood platelet counts in 23 of the cases. The figures, released late Friday, are up-to-date through April 2. Eight people died.Illinois Cases Jump (1:50 p.m. NY)Illinois, like many of its Midwestern neighbors, is seeing cases jump even as its daily vaccinations accelerate to stop the pandemic. Confirmed and probable cases on Friday rose to 4,004, the highest since late January, as the number of daily vaccinations reported rose to a record 164,462, according to the state department of public health.Vaccine eligibility will expand to all residents 16 and over statewide on April 12. More than 80 of Illinois’s 102 counties had already begun opening up to younger adults before the statewide eligibility expanded.Germany Reported to Weigh Curfews (1:39 p.m. NY)Germany’s first draft of an agreement between federal and state officials for unified nationwide lockdown rules to curb Covid-19 infections includes a nightly curfew and business closures, Business Insider reported.A 9 p.m. to 5 a.m. curfew would be triggered when local seven-day incidence rates rise above 100 infections per 100,000 people, according to the report.Pfizer Seeks Approval for Young Teens (1:15 p.m. NY)Pfizer and its partner BioNTech SE said they would ask regulators in the U.S. and elsewhere to allow use of their Covid-19 vaccine in adolescents ages 12 to 15.The companies said in a statement that they had requested that the U.S. Food and Drug Administration expand the vaccine’s emergency-use authorization and that they plan to request similar rulings from other regulators worldwide in coming days.If the requests are granted, it could pave the way for many more schoolchildren to be vaccinated before the next school year.J&J Shots to Resume in N. Carolina (12:58 p.m. NY)A healthcare provider in North Carolina will resume giving Johnson & Johnson vaccines on Saturday after as many as 10 people experienced fainting or dizziness on Thursday after receiving shots. None of the apparent side effects were serious, said Alan Wolf, a spokesman for UNC Health, though the provider suspended J&J vaccines Thursday and Friday.UNC Health conferred with the U.S. Centers for Disease Control and Prevention as well as state health officials, who determined there were no safety issues with the J&J shots, he said. Wake County, which includes the capital of Raleigh, also suspended J&J shots after mild reactions Thursday.Italy Relaxes Restrictions (11:31 a.m. NY)Italy eased lockdown restrictions, lifting some curbs that have been weighing on the economy in the region surrounding Milan and across the country as the latest virus resurgence slows.Health Minister Roberto Speranza will sign a decree later on Friday to shift six regions classified as high-risk “red” areas to medium-risk “orange” status, his office said in a statement.Michigan Seeks Aid Amid Surge (10:35 a.m. NY)Governor Gretchen Whitmer called for Michiganders to voluntarily suspend social activities for two weeks, and asked the federal government to prioritize additional vaccines to the state, to help slow the spread in the hottest Covid-19 spot in the nation.The U.S. needs a program that allocates additional vaccines to states that are experiencing surges, Whitmer said Friday at a press briefing. In the meantime, she urged high schools to shift to remote learning, diners to avoid indoor seating and youth sports to suspend games and practices.“There is a light at the end of the tunnel, but the data shows that we are still in the tunnel,” Whitmer said during a press briefing. “We’re going to have some tough weeks ahead so I’m asking everyone to please take this seriously. The numbers show young people are not impervious to this virus as we see more cases with teens.”EU Seeks Up to 1.8 Billion Doses (9.20 a.m. NY)The European Commission plans to publish tenders for up to 1.8 billion additional vaccine doses in the coming days, according to a commission official.These include booster shots and doses for children and will mainly concern vaccinations in 2022 and 2023, the official said.WHO Warns on Covid Trajectory (8:24 a.m. NY)The pandemic is on the wrong trajectory after six weeks in a row of increases in cases and deaths, according to Maria van Kerkhove, the World Health Organization’s technical lead officer on Covid-19.“Vaccines will not end the pandemic,” she said at a media briefing, saying physical distancing, wearing masks, avoiding crowds and working from home are tools that need to go hand-in-hand with vaccine rollouts.Separately, the WHO is expediting the review of more vaccines, including Sinopharm, Sinovac and Sputnik V. The Chinese shots are in the final stages of evaluation, and an expert group will convene on April 26 for an assessment, according to Rogerio Pinto de Sa Gaspar, WHO’s director for regulation and pre-qualification.EU Reviews J&J Shot After Clots (7:14 a.m. NY)Four serious cases of unusual clots accompanied by low blood platelets, one of which was fatal, have emerged after vaccination with Johnson & Johnson’s Covid-19 vaccine, the European Medicines Agency said Friday.The EU is relying on the one-shot vaccine to boost its immunization drive amid restrictions in some countries on use of the AstraZeneca shot, which is delivered in two doses. J&J said in a statement that no clear causal relationship had been established between its vaccine and clotting events.Germany Doubles Vaccine Pace (5:13 p.m. HK)The country administered about 720,000 doses on Thursday, a fourth straight daily record, thanks to a surge in vaccinations being performed in doctors’ offices, Health Minister Jens Spahn said Friday at a news conference.That pace should continue for most of April as a network of 35,000 general practitioners offices get 1 million doses more in each of the next two weeks, and more after that.For more articles like this, please visit us at bloomberg.comSubscribe now to stay ahead with the most trusted business news source.©2021 Bloomberg L.P.