The Honda rider broke his right humerus in a crash during last July's Spanish Grand Prix, and has been out of action since making an aborted comeback at the following week's Andalusian GP having just undergone surgery.
Marquez has had two operations since, the latest in December – where he underwent a bone graft – finally pointing his recovery in the right direction.
His third operation was thought to come with a six-month recovery period, but HRC has yet to give an official update on this.
Speaking during Honda's 2021 launch presentation video, Marquez admits he nor his doctors know when he will be able to ride again.
"Yeah, of course step-by-step I feel much better, and the recovery is going in a good way," Marquez said.
"Every time I go to the doctor, normally we have good news.
"That is really important because last year was quite long and tough. But now just we try to follow my body, with the physio, with the doctor, try to increase a little bit the work at home.
"But I don't know and the doctors don't know when I will be ready.
"But the most important thing is every week – not every day – but every week I feel a bit better and I'm optimistic to be on the bike as soon as possible.
"But I don't know exactly when will be the day."
When asked what version of Marquez can be expected when he returns, he replied: "It's the first time in my life, my career, that it's been nine months, 10 months without [riding a] bike, with a big injury.
"For sure the first time I ride the bike I will not be 100% because one thing is being 100% in the bone side, and then 100% on the muscles.
"We will see. Of course, I imagine the best comeback, which is starting again and being the same, but it will be difficult to be like this.
"But we will see if it takes one race, two races, half season to be the same Marc [as before]."
