There are 4,000 variants of virus that causes COVID-19, UK minister says

Thousands of variants of the type of coronavirus that causes COVID-19 have been documented as the virus mutates, including the so-called British, South African and Brazilian variants which appear to spread more swiftly than others.

Reuters
February 04, 2021 / 02:35 PM IST

There are around 4,000 variants of the virus that causes COVID-19 around the world now so all vaccine manufacturers including Pfizer Inc and AstraZeneca Plc are trying to improve their vaccines, a British minister said.

Thousands of variants of the type of coronavirus that causes COVID-19 have been documented as the virus mutates, including the so-called British, South African and Brazilian variants which appear to spread more swiftly than others.

"Its very unlikely that the current vaccine won't be effective on the variants whether in Kent or other variants especially when it comes to severe illness and hospitalisation," Vaccine Deployment Minister Nadhim Zahawi told Sky News.

"All manufacturers, Pfizer-BioNTech, Moderna, Oxford-AstraZeneca and others are looking at how they can improve their vaccine to make sure that we are ready for any variant - there are about 4,000 variants around the world of COVID now."

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COVID-19 Vaccine

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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While thousands of variants have arisen as the virus mutates on replication, only a very small minority are likely to be important and to change the virus in an appreciable way, according to the British Medical Journal.

"We have the largest genome sequencing industry - we have about 50% of the world's genome sequencing industry - and we are keeping a library of all the variants so that we are ready to respond - whether in the autumn or beyond - to any challenge that the virus may present and produce the next vaccine," Zahawi said.

The novel coronavirus - known by scientists as SARS-CoV-2 - has killed 2.268 million people worldwide since it emerged in China in late 2019, according to Johns Hopkins University of Medicine.

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Reuters
TAGS: #coronavirus #Covid-19 #COVID-19 vaccine #Health #UK #World News
first published: Feb 4, 2021 02:25 pm