Calls have grown for Boris Johnson to extend the post-Brexit transition period to deal with spiking coronavirus cases and travel chaos as countries shut their borders with Britain.
A growing list of places are banning travel from the UK, and France has gone one step further by blocking all incoming accompanied trade, meaning hauliers and lorries are backed up in Kent.
Conservative MPs as well as senior figures from other parties including Scotland's First Minister Nicola Sturgeon and Mayor of London Sadiq Khan have now called for the prime minister to request post-Brexit trade talks be pushed into the new year.
Chief negotiators Michel Barnier and Lord Frost met in Brussels on Sunday - the day the European Parliament said a deal needed to be done to ensure it could be signed off before the transition period ends on 31 December.
But they failed to reach a breakthrough, with a UK government source describing the situation as "difficult" with key differences remaining on fishing and state aid for business.
Ms Sturgeon said Britain faced a "profoundly serious situation" with the new mutation of COVID-19, which "demands our 100% attention".
"It would be unconscionable to compound it with Brexit," she tweeted on Sunday night.
Simon Hoare, a Tory MP and chair of the Commons' Northern Ireland affairs select committee, also said he wanted the clock "temporarily stopped" on trade talks.
"There's no parliamentary time to scrutinise and agree a deal and daily clarity of the dangers to our already pressured economy of no-deal is alarming," he tweeted. "Time for maturity."
And another backbench Conservative, Tobias Ellwood, made a similar urge, saying: "If there's no deal by new year, let's do what's best for the UK & pause the clock."
Mr Khan also confirmed he wants the transition period extended.
"Securing our key supply chains and fighting the coronavirus pandemic requires the full and undivided efforts of ministers more than ever before," he added.
Prime Minister Boris Johnson will hold an emergency meeting of the government's Cobra committee on Monday to try to prevent UK food shortages after France banned all freight from the UK.
A string of EU countries, including Germany, Italy, the Netherlands, Austria and Ireland, have all restricted travel to the UK over concerns about the new strain - thought to be up to 70% more transmissible.
The Port of Dover has been closed to all traffic - both freight and passengers - amid the French travel ban.
It comes as EU chief negotiator Mr Barnier has said Brexit trade talks are at a "crucial moment".
The UK side has accused the EU of making "unreasonable demands" on fishing rights and competition rules.
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Sources have warned there will be no deal unless there is a "substantial shift" in position from the EU.
Health Secretary Matt Hancock told Sophy Ridge on Sunday: "We want these talks to reach a positive conclusion. I think everybody wants a deal.
"Unfortunately, the EU have put in some unreasonable demands. I'm sure that a deal can be done but obviously it needs movement on the EU side."
Originally, the EU claimed there would need to be an agreement by 20 December if EU leaders were to have time to ratify it by the end-of-year deadline.
If a deal does come later, EU rules would allow leaders to sign it off provisionally, but delay ratification until 2021.
But if there is no agreement by New Year's Eve, the UK will leave the single market and customs union and have to trade with the EU on World Trade Organisation terms - which risks the imposition of tariffs and the price of goods going up.
