A statement from the agency said the scientists involved would use a $1 million Australian Government grant given to the firm Anatomics to develop what they called "a smart helmet to monitor brain swelling in stroke and traumatic brain injury patients".
Dr Umut Guvenc, a researcher at CSIRO's digital arm Data 61, pointed out that traumatic brain injuries affected more than 69 million people globally, including 700,000 Australians.
One in three of those affected was likely to develop chronic epilepsy due to the high number of seizures.
"These seizures are often difficult to detect, with current monitoring techniques only able to be used in a hospital using bulky devices for less than 24 hours, providing a brief snapshot of brain activity during that time only.
"This new method can continuously monitor brain activity wirelessly, allowing the patient to be mobile, comfortable and more socially active."
The device was trained using data from Monash University and can spot even the tiniest seizure, before it sends the data from the "helmet" to the doctor.
Peter Marendy, a senior research engineer at Data61, said: "Information provided by the implants can be used to inform clinicians about the patient's brain activity and inform decisions regarding the administering of drugs.
"The combination of brain swelling, surgery timing and patient outcome data will enable further study on the ideal time to perform a reconstructive cranioplasty to achieve the best patient outcome – research that will ultimately influence future medical decisions."
Dr Ganesha Thayaparan, an R&D fellow at Anatomics, said: "Anatomics' ongoing collaboration with CSIRO has produced a number of medical world-firsts, including additively manufactured patient-specific titanium implants.
"The 'smart helmet' project builds upon our existing SkullPro technology to develop a remote sensing platform to monitor the injured brain following a decompressive craniectomy."
The research was enabled by CSIRO's Probing Biosystems Future Science Platform, which provided the initial funding.
Graphic courtesy CSIRO