Last Updated : Nov 23, 2020 09:26 PM IST | Source: Reuters

COVID-19 vaccine | Serum Institute to focus on supplying coronavirus drug to India first

The SII remains in discussion with the Indian government about inking a purchase agreement for the vaccine.

Reuters

The Serum Institute of India, the world's largest manufacturer of vaccines by volume, will first focus on supplying AstraZeneca Plc's COVID-19 vaccine to Indians before distributing it to other countries, Serum's Chief Executive Adar Poonawalla said on Monday.

"It's very important we take care of our country first, then go on to COVAX after that and then other bilateral deals with countries. So I've kept it in that priority," said Poonawalla, referencing the global COVAX facility, which has been set up to provide COVID-19 vaccines to poorer countries.

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The company remains in discussion with the Indian government about inking a purchase agreement for the vaccine, Poonawalla said in an interview with CNBC-TV 18, adding that Serum should have quantities of it ready to sell into India's private market in the first quarter of 2021.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Poonawalla's comments came shortly after AstraZeneca said on Monday its vaccine could be around 90% effective, giving the world's fight against the pandemic a new weapon, cheaper to make, easier to distribute and faster to scale up than rivals.

Serum is hoping the data released earlier on Monday, along with preliminary data from the ongoing trial of the vaccine in India, will allow it to seek emergency use authorisation for the vaccine by year-end, before gaining approval for a full rollout by February or March next year, said Poonawalla.

He said the vaccine in the Indian private market would be priced at 1,000 rupees per dose ($13.50), but that governments signing large supply deals would likely buy it at lower prices.

Poonawalla also said that although Serum has the right to strike direct bilateral deals with more than five dozen nations, on the basis of its licensing deal with AstraZeneca, the company may include the government in some of these discussions.

Poonawalla said the company will be able to produce 400 million doses of AstraZeneca's vaccine by July 2021 and scale up further from there.
First Published on Nov 23, 2020 09:26 pm

tags #Adar Poonawalla #AstraZeneca #Business #COVID-19 vaccine #SII