Baker Mayfield's first quarter Sunday against Cincinnati couldn't have gone any worse.

But from then on, the Cleveland Browns quarterback was perfect.

Literally.

Mayfield rebounded from a 0-of-5 start, including an interception on his first throw, to break a franchise record with 21 consecutive completions, propelling Cleveland to a thrilling 37-34 comeback victory over the Bengals.

Mayfield finished 22 of 28 passing with 297 yards and five touchdowns, with three coming in a wild back-and-forth fourth quarter.

His final touchdown was a game-winning 24-yard strike to rookie Donovan Peoples-Jones with just 15 seconds remaining. His only incompletion after the first quarter was a spike to stop the clock on the final drive.

Mayfield passed Bernie Kosar (1989) and Kelly Holcomb (2003), who previously shared the Browns' record with 16 straight completions. No other Cleveland quarterback in the last 30 seasons had tossed three touchdowns in a fourth quarter, either, according to ESPN Stats & Information, and none since Derek Anderson in 2007 had thrown five in a game.

Mayfield out-dueled Cincinnati rookie quarterback Joe Burrow in a shootout of former Heisman Trophy winners and No. 1 overall picks.

Burrow completed 35 of 47 passes for 406 yards, the first 400-yard passing game of his pro career. Despite losing three starting offensive linemen to injury during the game, Burrow also threw three touchdowns and rushed for another. On fourth-and-1, he connected on a 3-yard, go-ahead touchdown pass to running back Giovani Bernard with just over a minute to play, which set up Mayfield's late-game heroics.

According to the Elias Sports Bureau, it was the first game in NFL history with five go-ahead touchdown passes in a fourth quarter.

ESPN's Ben Baby contributed to this report.