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Santa Fe BioLabs Granted Patent for Identification System of Viable Candida auris

A Tool to Prevent the Next Pandemic by a Deadly Fungus

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Santa Fe BioLabs LLC

Oct 15, 2020, 08:32 ET

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FORT WORTH, Texas, Oct. 15, 2020 /PRNewswire/ -- Pending FDA approval, Santa Fe BioLabs will be introducing AuriFindTM, a colony/culture classification assay to identify the fungus Candida auris, for which US patent #10662405 was recently granted. This yeast-like fungus is a growing concern for health authorities because of its increased incidence in hospitals worldwide and the difficulty of treatment when it becomes infectious. AuriFindTM provides a simple growth test on agar medium to determine if a suspected microbial clone is Candida auris or not. For most clinical strains, a positive result is obtained within 24-32 hrs. PCR-based assays are undoubtedly faster in detecting relevant DNA but do not distinguish between viable and unviable cells. AuriFindTM, however, identifies viable and thus potentially infectious cells. Its ease of use makes it suitable even for poorly equipped laboratories.

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Drops of 36 cell suspensions representing 24 different yeast species were randomly selected, tested in the shown grid on an AuriFind(TM) plate and analyzed after 24 and 48 h. The seven growing samples correctly identify strains of Candida auris.

Isolation and propagation of viable Candida auris cells are also necessary to choose the right drug for the strain in question. While AuriFindTM is not a direct selection system and requires previous growth of suspicious microbial clones, Santa Fe BioLabs also offers ReCandTM broth which is designed for maximum recovery of Candida auris from skin and dry environments. The combination of ReCandTM broth and AuriFindTM provides speedier answers and higher sensitivity than the dulcitol/salt enrichment medium previously introduced by the CDC for the same purpose.

"COVID19-related extensive use of ventilators and hospital procedures together with suboptimal hygiene may provide a favorable environment for the spread of Candida auris," stated Wolfram Siede, PhD, CEO and Principal Scientist of Santa Fe BioLabs LLC. "Recent reports by the LA County Department of Public Health confirmed these concerns (https://www.latimes.com/california/story/2020-07-20/potentially-deadly-fungus-outbreak-los-angeles-county-healthcare-facility). Another pandemic may be starting. So far, the spread of this very persistent organism has remained confined to hospitals and long-time care facilities. However, unlike coronavirus, its consequences are quite often deadly and no therapy is in sight. Alongside molecular methods, AuriFindTM and ReCandTM will be important tools in identifying and preventing the spread of Candida auris."

Santa Fe BioLabs LLC is a start-up biotech company with focus on discovery and consulting in the areas of antimicrobials, microbial diagnostics, cancer research and healthcare consumer products.

For more information, visit www.santafebiolabs.com

Contact:

Wolfram Siede,    


Santa Fe BioLabs LLC

Phone:

+1 817 808 7747

Email:

[email protected]

SOURCE Santa Fe BioLabs LLC

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