Slovenian Bedene first called for the physiotherapist to get treatment on his right ankle. At that time, he was down 0-5 in the opening set. After returning to court, Bedene won his first game and then got his ankle strapped before the start of the second set.

Greek Tsitsipas, the reigning ATP Finals champion, kept his focus and went about his business smoothly, hitting 28 winners and breaking Bedene’s serve five times before the 31-year-old decided he could no longer continue. Meanwhile, Russian Andrey Rublev strolled into the fourth round with a facile 6-3, 6-2, 6-3 win over South African Kevin Anderson.

Rublev, seeded 13th at Roland Garros, did not face a single break point against the 34-year-old. German qualifier Daniel Altmaier, ranked 186th in the world, bundled out seventh seed Matteo Berrettini (Italy) with a comprehensive 6-2, 7-6(5), 6-4 victory.

In women’s singles, Sofia Kenin’s campaign gathered momentum as the American fourth seed stormed into the fourth round with a 6-2, 6-0 demolition of Romanian qualifier Irina Bara. Tunisia’s Ons Jabeur became the first Arab woman to reach the fourth round of the French Open as she beat eighth seed Aryna Sabalenka 7-6(7), 2-6, 6-3.