Last Updated : Sep 23, 2020 10:59 PM IST | Source: PTI

Anthony Fauci says scientists may know if COVID-19 vaccine is safe and effective by December

As the government’s leading infectious disease expert, Anthony Fauci has been a realist about the dangers of the coronavirus but also optimistic about the prospects for a vaccine.

PTI

Dr Anthony Fauci says by the end of this year government scientists should know whether they have a safe and effective vaccine for COVID-19.

Fauci is among top officials testifying before the Senate Health, Education, Labour and Pensions committee on Wednesday.

As the government’s leading infectious disease expert, Fauci has been a realist about the dangers of the coronavirus but also optimistic about the prospects for a vaccine.

Fauci says people who recover from the virus develop antibodies against it, which gives him confidence a vaccine that triggers the immune system will work.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Fauci says several kinds of vaccines are in final-stage testing in the US. A single-dose candidate is the most recent trial, which requires thousands of volunteers.

Follow our full coverage of the coronavirus pandemic here.
First Published on Sep 23, 2020 10:53 pm