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Coronavirus Live Updates: With 83,347 cases in last 24 hours, India’s cases cross 56 lakh mark; death toll at 90,020

Coronavirus (Covid-19) India News Live Updates: India’s top drug regulator CDSCO has said it will only approve Covid-19 vaccines that meet parameters, such as their ability to show they can improve clinical outcomes by at least 50 per cent during human testing. 

By: Express Web Desk | Ahmedabad, Bengaluru, Chennai, Kochi, Mumbai, New Delhi, Panaji | Updated: September 23, 2020 10:57:13 am
coronavirus, coronavirus news, coronavirus today news, covid 19 vaccine, unlock 5.0, lockdown unlock 5.0, coronavirus vaccine, coronavirus india, coronavirus india news, corona cases in india, india news, coronavirus news, covid 19 india, corona news, corona latest news, india coronavirus, coronavirus live news, coronavirus live update, covid 19 tracker, india covid 19 tracker, corona cases in india, corona cases in indiaCoronavirus India LIVE updates: Construction labourers get screened for Covid-19 in New Delhi on Tuesday.

Coronavirus India News Live Updates: With India recording 83,347 cases of the novel coronavirus in the 24 hours ending 9 am Wednesday, the total number of cases in the country crossed the 56 lakh mark to reach 5,646,011. Also, as many as 1,085 deaths during the same period took the toll to 90,020. The fatality rate is 1.60 per cent. At present, the country has 9,68,377 active cases and as many as 45,87,614 people have been treated and discharged.

The number of people who recovered from Covid-19 stood at over 1.01 lakh on Monday, the highest single- day rise so far. The recovery rate stands at 80.86 per cent. With India recording the highest number of COVID-19 recoveries in the world, the government on Tuesday said that for the past four consecutive days the number of daily recovered cases surpassed the new infections reported per day.

Also, September has been particularly harsh for Maharashtra, which has consistently had the highest number of coronavirus cases in the country. As coronavirus spreads to rural areas, hospitals like Karad’s in Maharashtra are struggling. Again declared Covid-only this month, the Sub-District Hospital has 45 beds and none in ICU due to the lack of an intensivist and oxygen tank.

Meanwhile, the Central Drugs Standard Control Organisation (CDSCO), India’s top drug regulator, will only approve Covid-19 vaccines that meet parameters, such as their ability to show they can improve clinical outcomes by at least 50 per cent during human testing.

Globally, as many as 31,480,193 people have deen infected while 968,726 have succumbed to the virus. Also, 21,624,431 poeple have recovered so far.

Live Blog

Coronavirus LIVE updates: India has over 56 lakh cases, over 90,000 deaths; recovery rate is 80.86 per cent; Globally, 31,480,193 people have been infected. Follow latest updates here

10:57 (IST)23 Sep 2020
Unlockdown: Children in custodial care institutions hopeful of repatriation, reunion with families

The phased ‘unlockdown’ has raised hopes among children lodged in custodial care institutions in the city, who are awaiting repatriation to their home countries or reunion with their families in other states.

At the Children Aid Society’s home in Dongri, 36 children are awaiting reunion with their families since March, held up by delayed procedures, limited trains and permissions from their states. The home also has four children from other countries, including Nepal and Bangladesh, awaiting travel permits to return.

Counsellors and home officials who interact with the children say that initially when they were told about Covid-19 and the resulting lockdown, many refused to believe the outside world had changed so much and that there were severe restrictions on movement, including suspension of all forms of transport. Officials then made them watch news on TV so they could understand what the situation was beyond the high walls of the home. “Now, when they see that trains have resumed functioning and many restrictions have been eased, their questions have increased. It has been a difficult time for them, they are in a lockdown within a lockdown,” says Diana Quadros, a counsellor at the home.

10:39 (IST)23 Sep 2020
UK's Johnson urges 'spirit of togetherness' to combat virus

British Prime Minister Boris Johnson appealed Tuesday for resolve and a "spirit of togetherness" through the winter as he unveiled new restrictions on everyday life to suppress a dramatic spike in coronavirus cases. Warning that the measures could last for six months, Johnson voiced hope that "things will be far better by the spring" when a vaccine and mass testing could be in place.

The most high-profile change centered on pubs, restaurants and other entertainment venues in England, which from Thursday must close at 10 pm In a change of emphasis, Johnson urged people to work from home where possible. He said stiff fines will be imposed on anyone breaking quarantine rules or gathering in groups of more than six, while the use of face masks will be expanded to include passengers in taxis and staff at bars and shops.

10:29 (IST)23 Sep 2020
‘Covid vaccine should better clinical results by at least 50% for approval’
This means that Covid vaccines approved in India must be able to reduce the frequency of those inoculated being clinically diagnosed with the disease by 50 per cent or higher, according to experts. (File)

The Central Drugs Standard Control Organisation (CDSCO), India’s top drug regulator, will only approve Covid-19 vaccines that meet parameters, such as their ability to show they can improve clinical outcomes by at least 50 per cent during human testing. This means that Covid vaccines approved in India must be able to reduce the frequency of those inoculated being clinically diagnosed with the disease by 50 per cent or higher, according to experts.

The regulator, which released a new set of guidelines for Covid-19 vaccines on Monday, also emphasized that the statistical range of efficacy (the ability to produce the desired outcome) in the human trials cannot be lower than 30 per cent.

The guidelines come several months after the World Health Organization (WHO) and the US Food and Drug Administration (US FDA) released their own guidelines for Covid-19 vaccine approvals and draw from both documents, according to experts that have been closely tracking and involved in Covid-19 vaccine developments.

10:25 (IST)23 Sep 2020
First Covid lay-offs by BCCI: 11 coaches at national academy; they say were not alerted
Dravid, BCCI president Sourav Ganguly and board secretary Jay Shah did not respond to queries from The Indian Express. (File)

NO INDIA matches since February, its showpiece IPL playing out in a bio-bubble of empty stands in the UAE, the world’s richest cricket body is now quietly tightening its belt.

Marking its first big staff lay-offs since the Covid outbreak, the BCCI has decided to not renew the annual contracts of 11 coaches at its premier National Cricket Academy (NCA), including five retired India players —Ramesh Powar, SS Das, Hrishikesh Kanitkar, Subroto Banerjee and Sujith Somsundar.

The Indian Express has learnt that former India captain Rahul Dravid, who had handpicked the team after taking over as Head of Cricket at NCA, informed the coaches last week about the termination of their services. Those who have been asked to leave include domestic stalwart Sitanshu Kotak.

09:45 (IST)23 Sep 2020
Latest Covid numbers | With 83,347 cases in last 24 hours, India’s cases cross 56 lakh mark; death toll at 90,020

With India recording 83,347 cases of the novel coronavirus in the 24 hours ending 9 am Wednesday, the total number of cases in the country crossed the 56 lakh mark to reach 5,646,011. Also, as many as 1,085 deaths during the same period took the toll to 90,020. The fatality rate is 1.60 per cent. At present, the country has 9,68,377 active cases and as many as 45,87,614 people have been treated and discharged.

09:37 (IST)23 Sep 2020
As September Covid-19 surge sweeps rural Maharashtra, hunt for beds
Since September 1, Satara has recorded 16,000 cases, with Karad the epicentre. (File)

For three days earlier this month, 65-year-old Kashabha Kumbhar lay outside the Karad Sub-District Hospital as his family, which had made its way there from a village 20 km away, hunted for a hospital bed. It was only when Kumbhar turned critical that the hospital admitted him on September 10.

The Karad hospital had been converted into a Covid facility in March, but as cases lagged, had gone back to taking in other patients. Now, as coronavirus spreads to rural areas, hospitals like Karad’s in Maharashtra are struggling. Again declared Covid-only this month, the Sub-District Hospital has 45 beds and none in ICU due to the lack of an intensivist and oxygen tank.

Accounting for 54% of the state’s 11.23 crore population, rural Maharashtra had only 16.5% of its coronavirus cases till mid-July

09:32 (IST)23 Sep 2020
Welcome to our coronavirus LIVE blog

Welcome to our coronavirus LIVE blog. The total number of cases in the country at present stands at 55,62,664 and the death toll is 88,935. The fatality rate is 1.60 per cent. The number of people who recovered from Covid-19 stood at over 1.01 lakh on Monday, the highest single- day rise so far. This took the country’s recovery count to 44,97,868, and the recovery rate to 80.86 per cent. Follow this space for all the latest updates.

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Coronavirus India LIVE updates

The Central Drugs Standard Control Organisation (CDSCO), which released a new set of guidelines for Covid-19 vaccines on Monday, also emphasized that the statistical range of efficacy (the ability to produce the desired outcome) in the human trials cannot be lower than 30 per cent.

The guidelines come several months after the World Health Organization (WHO) and the US Food and Drug Administration (US FDA) released their own guidelines for Covid-19 vaccine approvals and draw from both documents, according to experts that have been closely tracking and involved in Covid-19 vaccine developments.

“To ensure that a widely deployed Covid-19 vaccine is effective, the primary efficacy endpoint point estimate for a placebo-controlled efficacy trial should be at least 50 percent, and the statistical success criterion should be that the lower bound of the appropriately alpha-adjusted confidence interval around the primary efficacy endpoint point estimate is (greater than) 30 percent,” stated CDSCO.

“What this essentially translates to is that the trial size has to be sufficient so that if the investigators get exactly 50 percent efficacy, we should have confidence that it will not be less than 30 percent,” said vaccine scientist and Christian Medical College, Vellore professor Dr Gagandeep Kang.

Meanwhile, marking its first big staff lay-offs since the Covid outbreak, the BCCI has decided to not renew the annual contracts of 11 coaches at its premier National Cricket Academy (NCA), including five retired India players —Ramesh Powar, SS Das, Hrishikesh Kanitkar, Subroto Banerjee and Sujith Somsundar.

The Indian Express has learnt that former India captain Rahul Dravid, who had handpicked the team after taking over as Head of Cricket at NCA, informed the coaches last week about the termination of their services. Those who have been asked to leave include domestic stalwart Sitanshu Kotak.

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