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Coronavirus LIVE Updates: India's Covid-19 Tally Crosses 50 Lakh-mark, 1,290 Deaths in 24 Hours; Serum Institute to Resume Vaccine Trial

News18.com | September 16, 2020, 10:31 AM IST
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Coronavirus LIVE Updates: India crossed yet another grim milestone of 50 lakh Covid-19 cases with a spike of 90,123 new cases and 1,290 deaths, the highest in 24 hours so far, the Union Health Ministry has said. The total number of people who have died because of the disease now stands at 80,776. The total number of coronavirus cases now stands at 50,20,360, including 9,95,933 active cases, which comprises 20.08 per cent of the total caseload, the data stated. India's recovery rate rose to 78.28 per cent. A total of 39,42,361 patients stand cured.

Drugs Controller General of India (DCGI) Dr VG Somani has given permission to Serum Institute of India to resume clinical trial of the Oxford COVID-19 vaccine candidate in the country while revoking its earlier order of suspending any new recruitment for phase two and three trial. The DCGI, however, put certain conditions like taking extra care during screening, providing additional information in informed consent and close monitoring for adverse events during follow-up of the study which have to be “scrupulously” followed by Serum Institute of India (SII). SII has also been asked to submit to the DCGI's office details of medication used in accordance with the protocol for management of adverse events.
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Today's Data Highlights

- India crosses 5 million cases. 4 million to 5 million in 13 days. 4 states (Maharashtra, Andhra Pradesh, Tamil Nadu and Karnataka) account for 53% of total cases in India. 

- New cases again over 90k after 83.8k the previous day.

- 1290 new deaths of which 515 from Maharashtra alone. 15th consecutive day of more than 1k daily deaths 

- High of about 83k new recoveries. India's recovery rate is now at 78.5%

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Coronavirus LIVE Updates: India's Covid-19 Tally Crosses 50 Lakh-mark, 1,290 Deaths in 24 Hours; Serum Institute to Resume Vaccine Trial
Image for representation.

The DCGI had on September 11 directed Serum Institute of India to suspend any new recruitment in the phase two and three clinical trial of the Oxford COVID-19 vaccine candidate till further orders in the backdrop of pharma giant AstraZeneca pausing the clinical trials in other countries because of ”an unexplained illness” in a participant in the study. On Saturday, British-Swedish biopharmaceutical giant AstraZeneca and the University of Oxford said clinical trials for their coronavirus vaccine have resumed in the UK after the Medicines Health Regulatory Authority’s (MHRA) confirmed that the trials were safe. SII, which has partnered with AstraZeneca for manufacturing the vaccine candidate for COVID-19, on Tuesday submitted the recommendations of the Data and Safety Monitoring Board (DSMB), UK and DSMB, India, and requested for permission to restart enrolment in the clinical trial.

According to Tuesday's order issued by DCGI, the DSMB, UK, recommended that the investigators recommence all immunization in their clinical trials subject to certain conditions. DSMB, India, also has recommended to continue the study and enroll the remaining participants in the clinical trial as per protocol subject to certain conditions.

The World Health Organization has said that Europe was facing decision time about tackling Covid-19 as case numbers hit record highs, children return to school and summer recedes. WHO emergencies director Michael Ryan said it was time to "stop looking for unicorns" and instead take hard decisions to protect those most vulnerable and keep youngsters in education -- but inevitably see others lose out. "Europe is facing that moment as Europe enters into a season in which people will begin to come back indoors. The pressure of infection will grow, no question," Ryan told a virtual press conference. "How do we hold those two principles -- protecting the vulnerable from death, and getting our children back to school? "Something, in some sense, has to give."

Ryan said there were no easy answers but such trade-offs needed to be made to help both the youngest and the oldest in society. "The only way to do that is that the adults separate themselves enough to drive transmission downwards," he said. "So what is more important: our children back at school or the nightclubs and bars open? "There's a time for decision-making coming as the season rolls into the winter months."

The WHO registered a one-day record high number of confirmed cases in Europe on Friday at 53,873. The surge has sparked alarm across Europe, and revived the debate over how best to fight it as millions of schoolchildren return to the classroom for the first time in months. Maria Van Kerkhove, the WHO's technical lead on Covid-19, said the increase in cases in Europe was partly due to a welcome improvement in testing capacity and surveillance.

However she added: "Some of that resurgence is reaching levels that are higher than we saw in April and in May. That is a worrying trend that we are definitely seeing. "If the virus is present and there are gatherings taking place, particularly in crowded settings, indoor locations with poor ventilation, the virus will spread." Ryan and Van Kerkhove were addressing speaking a press conference by the WHO, the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the UN Children's Fund (UNICEF) on getting youngsters back to school during the pandemic.

They have published joint updated guidance on school-related public health measures under the Covid-19 crisis.

"There is no zero risk," said WHO chief Tedros Adhanom Ghebreyesus. "But with the right combination of measures, we can keep our kids safe and teach them that health and education are two of the most precious commodities in life." Nine months into the crisis, a clearer picture was emerging on how the new coronavirus affected children, he said, though many questions remained unanswered.

People under 20 accounted for less than 10 percent of cases and less than 0.2 percent of deaths. Tedros said schools should only be closed "as a last resort" in areas with intense transmission. UNESCO chief Audrey Azoulay said half the global student population was yet to return to school and there was a risk that 11 million girls might never return. For UNICEF chief Henrietta Fore: "The sheer number is nothing short of a global education emergency."

Meanwhile, a World Health Organization special envoy on Covid-19 has said the world is still at the beginning of the coronavirus pandemic. Dr David Nabarro described the situation as “grotesque” during a sitting of the UK’s foreign affairs committee. He told MPs: “It’s much worse than any of the science fiction about pandemics. This is really serious - we’re not even in the middle of it yet. We’re still at the beginning of it. And we’re beginning to see what damage it’s going to cause the world. And it’s getting nastier as we go into this particular phase in Europe of watching the thing come back again.”
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