Homicide detectives have been called in to investigate the suspected stabbing death of a man in Brisbane's north overnight.

The 50-year-old fled the Bray Park home and was able to make it to a service station about 100 metres up the road, leaving a trail of blood, before succumbing to his injuries.

Police said they were called to a disturbance between a man and a woman on Gloucester Crescent just after 11.30pm on Saturday.

A crime scene was declared at the home after the man was found nearby. A 41-year-old woman is assisting police with their inquiries.

Neighbours have said the house was occupied by a family of four, including two young girls.

Anyone with information is asked to contact Policelink on 13 14 44 or Crime Stoppers on 1800 333 000.