Here is a look back at the search for Madeleine, who disappeared from a holiday apartment in Portugal in May 2007.
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Three-year-old Madeleine McCann, from Rothley, Leicestershire, went missing on 3 May 2007 while on holiday with her family in the Algarve, Portugal. This photo was taken the day she disappeared
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The following morning photos were put up in shop windows in the town of Praia da Luz close to where she was staying
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The same day, Madeleine's parents, Gerry and Kate McCann spoke to the press and made an emotional plea for her return
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Portuguese police searched outside the apartment where she went missing
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British tourists also joined the hunt in the area around the resort
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The story has became a major focus for the world's media since 2007 - here camera crews are gathered out the resort, six days after Madeleine disappeared
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One of the photographs issued by Madeleine's family showed her in an Everton football club shirt. Here Everton fans hold a banner calling for her safe return during a Premiership match against Chelsea in May 2007
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Kate and Gerry McCann leave church in Rothley, Leicestershire, after a service to mark the first anniversary of their daughter's disappearance
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In 2009, the Find Madeleine Campaign, set up by the family, released an image of how Madeleine might look aged six
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In 2011, Kate and Gerry McCann released a book about the case
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British police began reviewing the case in 2011 and launched a formal inquiry two years later. In 2014, forensic officers searched wasteland near Praia da Luz after Portuguese police reopened their investigation to run alongside Scotland Yard's
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In an interview with the BBC's Fiona Bruce in 2017, the McCann's said they would do "whatever it takes" to find their daughter