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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for April 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
THURSDAY, April 30, 2020 -- Screening symptomatic health care workers for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is feasible during the pandemic, according to a research letter published online April 22 in The Lancet.
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THURSDAY, April 30, 2020 -- Patients with glomerular disease and their caregivers give highest priority to outcomes of kidney function, mortality, and need for dialysis or transplant, but they also prioritize life participation and fatigue, according to a study published online April 30 in the Clinical Journal of the American Society of Nephrology.
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THURSDAY, April 30, 2020 -- At least half of older adults report experiencing a disruption to their medical care at one month into social distancing in response to the COVID-19 pandemic, according to a survey released April 27 by NORC at University of Chicago.
THURSDAY, April 30, 2020 -- The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean study published online April 15 in Scientific Reports.
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THURSDAY, April 30, 2020 -- For adult emergency department (ED) patients with syncope, serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) does not improve prognostication above the Canadian Syncope Risk Score (CSRS), according to a study published online April 28 in the Annals of Internal Medicine.
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THURSDAY, April 30, 2020 -- Food insecurity in the United States is high as a result of the COVID-19 pandemic, according to a survey released April 23 by the University of Arkansas Community and Family Institute.
THURSDAY, April 30, 2020 -- Mildly symptomatic patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often have alterations in smell or taste, according to a research letter published online April 22 in the Journal of the American Medical Association.
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THURSDAY, April 30, 2020 -- The presence of a mental disorder is associated with an increased risk for many subsequent medical conditions, according to a study on a Danish population cohort published online April 30 in the New England Journal of Medicine.
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THURSDAY, April 30, 2020 -- Cases of large-vessel stroke in individuals younger than 50 years are described in patients with COVID-19 in a case report published online April 28 in the New England Journal of Medicine.
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THURSDAY, April 30, 2020 -- For patients with COVID-19, male gender is associated with worse outcomes, independent of age, according to a study published online April 29 in Frontiers in Public Health.
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THURSDAY, April 30, 2020 -- A competition between researchers is part of a $1.5 billion program that seeks to speed development of accurate, quick, and easy-to-use COVID-19 tests, the U.S. National Institutes of Health (NIH) announced Wednesday.
THURSDAY, April 30, 2020 -- Total insurance coverage, Medicaid coverage, and mammogram rates are higher among lower-income women living in Medicaid expansion states versus nonexpansion states, according to a study published online April 6 in the Journal of the American College of Surgeons.
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THURSDAY, April 30, 2020 -- In 2018, 14.9 percent of U.S. adults had ever used an electronic cigarette (e-cigarette) and 3.2 percent were current users, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
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WEDNESDAY, April 29, 2020 -- Quantitative smell testing shows that decreased smell function is a major marker for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online April 17 in the International Forum of Allergy & Rhinology.
WEDNESDAY, April 29, 2020 -- Treatment disparities may explain worse outcomes for pediatric black and Hispanic brain cancer patients, according to a study recently published in Scientific Reports.
WEDNESDAY, April 29, 2020 -- More than one-quarter of health care workers with patient contact are at risk for poor outcomes from COVID-19, according to a study published online April 28 in the Annals of Internal Medicine.
MONDAY, April 27, 2020 -- Health care organizations are facing hard financial decisions amid the COVID-19 pandemic, but an end is in sight as some are beginning to slowly open back up around the country, according to David Shulkin, M.D. Shulkin, who served as ninth secretary for Veterans Affairs and is former president and CEO of Beth Israel Medical Center in New York, spoke with HealthDay during a live stream on the HealthDay YouTube channel and live blog.
WEDNESDAY, April 29, 2020 -- The U.S. Preventive Services Task Force (USPSTF) concludes that primary care-feasible behavioral interventions have a moderate net benefit for preventing tobacco use in children. These findings form the basis of a final recommendation statement, published online April 28 in the Journal of the American Medical Association.
WEDNESDAY, April 29, 2020 -- Patients with rheumatoid arthritis (RA) have low awareness about associated cardiovascular (CV) risk, according to a study published online April 20 in ACR Open Rheumatology.
WEDNESDAY, April 29, 2020 -- A considerable proportion of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have gastrointestinal manifestations, according to a study involving patients at a U.S. hospital published online April 10 in Gastroenterology.
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WEDNESDAY, April 29, 2020 -- For multiple sclerosis (MS) patients with clinically isolated syndrome, lower vitamin D and smoking predict worse long-term cognitive function and neuronal integrity, according to a study published online April 16 in Neurology.
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WEDNESDAY, April 29, 2020 -- Individuals at high risk for major depression reared in adoptive homes have a significantly reduced risk for major depression compared with those raised in their home environment, according to a study published online April 28 in the American Journal of Psychiatry.
WEDNESDAY, April 29, 2020 -- Multicancer blood testing combined with positron emission tomography-computed tomography (PET-CT) imaging can detect cancers, according to a study published online April 28 in Science to coincide with the virtual annual meeting of the American Association for Cancer Research.
WEDNESDAY, April 29, 2020 -- Prevention, diagnosis, and therapeutic management of thromboembolic complications in COVID-19 are discussed in a report published online April 23 in Radiology.
WEDNESDAY, April 29, 2020 -- Limited tools are available for identifying, diagnosing, and treating cognitive dysfunction from Alzheimer disease, according to three studies published online April 28 in the Annals of Internal Medicine.
TUESDAY, April 28, 2020 -- Climate change continues to make air pollution worse, with 45.8 percent of the U.S. population living in counties with unhealthy ozone or particle pollution, according to the American Lung Association (ALA) 21st annual State of the Air report.
TUESDAY, April 28, 2020 -- Vitamin D deficiency is associated with reduced overall survival for patients with multiple myeloma (MM), with a differential effect across race, according to a study published online April 21 in Blood Advances.
TUESDAY, April 28, 2020 -- Universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing of pregnant women presenting for delivery in New York City revealed that most positive patients were asymptomatic, according to a research letter published online April 13 in the New England Journal of Medicine.
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TUESDAY, April 28, 2020 -- Abdominal pain, gastrointestinal complaints, and heart inflammation are among the symptoms in children with a rare syndrome that may be linked to COVID-19, British health officials say.
TUESDAY, April 28, 2020 -- While health experts continued to call for a national strategy to test more Americans for coronavirus, President Donald Trump on Monday announced a "blueprint" for boosting testing capacity as some states began reopening their economies.
TUESDAY, April 28, 2020 -- Upward income mobility is associated with lower perceived stress and fewer depressive symptoms but with higher rates of metabolic syndrome, according to a study published online April 28 in the Journal of the American Heart Association.
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TUESDAY, April 28, 2020 -- Job strain is associated with a 1.41-fold increase in the average risk for peripheral artery disease (PAD) hospitalization, according to a study published online April 28 in the Journal of the American Heart Association.
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TUESDAY, April 28, 2020 -- An estimated 45.4 percent of U.S. adults may have an increased risk for COVID-19 complications due to chronic conditions, according to a study published in the August issue of Emerging Infectious Diseases.
TUESDAY, April 28, 2020 -- COVID-19 is associated with a high rate of pulmonary embolism, according to two research letters published online April 23 in Radiology.
TUESDAY, April 28, 2020 -- High-dosage chloroquine diphosphate (CQ) has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19, according to a study published online April 24 in JAMA Network Open.
TUESDAY, April 28, 2020 -- Social factors might be significant contributors to coexisting metabolic syndrome (MetS) and osteoporosis (OP) in postmenopausal women, according to a study published online April 20 in Menopause.
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TUESDAY, April 28, 2020 -- Pharmacologic treatment for type 2 diabetes increased from 2003 to 2016, according to a study published online March 31 in Diabetes Care.
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TUESDAY, April 28, 2020 -- Persons aged 60 to 69 years with COVID-19 are the most commonly hospitalized, according to a research letter published online April 24 in the Journal of the American Medical Association.
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MONDAY, April 27, 2020 -- Acute respiratory distress syndrome (ARDS) due to COVID-19 is associated with neurologic features, including encephalopathy, agitation, and confusion, according to a letter to the editor published online April 15 in the New England Journal of Medicine.
MONDAY, April 27, 2020 -- There is "no evidence" that people who have recovered from COVID-19 cannot be reinfected with the severe acute respiratory syndrome coronavirus 2, according to the World Health Organization.
MONDAY, April 27, 2020 -- Some companies are selling hand sanitizers with unproven claims that they will protect against COVID-19, the U.S. Food and Drug Administration warns.
MONDAY, April 27, 2020 -- On Monday, the U.S. Food and Drug Administration announced it was sending warning letters to 10 manufacturers to stop making products designed to allow youth to vape without getting caught by parents or teachers.
MONDAY, April 27, 2020 -- There are racial differences in pain management and pain outcomes for children seen in the emergency department for long-bone fractures, according to a study published online April 20 in Pediatrics.
MONDAY, April 27, 2020 -- The odds of postural instability are increased in older adults with moderate or worse hearing loss, even when hearing loss is present on only one side, according to a study published online April 23 in JAMA Otolaryngology-Head & Neck Surgery.
MONDAY, April 27, 2020 -- Use of monitoring with continuous pulse oximetry for infants with bronchiolitis who do not require supplemental oxygen varies widely by hospital, according to a study published in the April 21 issue of the Journal of the American Medical Association.
MONDAY, April 27, 2020 -- A single symptomatic COVID-19 infection results in direct medical costs of $3,045 in the United States, according to a study published online April 23 in Health Affairs.
MONDAY, April 27, 2020 -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not detected in the semen of patients one month after COVID-19 diagnosis, according to a study published online April 17 in Fertility and Sterility.
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MONDAY, April 27, 2020 -- In an international expert consensus statement, published online April 23 in Radiology: Cardiothoracic Imaging, recommendations are presented for chest imaging in pediatric COVID-19 patient management.
MONDAY, April 27, 2020 -- A number of former American-style football (ASF) players report clinician-diagnosed chronic traumatic encephalopathy (CTE), and they have significantly more comorbidities and cognitive impairment symptoms, according to a study published online April 13 in the Annals of Neurology.
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MONDAY, April 24, 2020 -- The use of smartphone-enabled health monitoring devices after myocardial infarction yields similar blood pressure control when compared with regular follow-up visits, according to a study published online April 16 in JAMA Network Open.
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
FRIDAY, April 24, 2020 -- The most common comorbidities among patients hospitalized with COVID-19 in the New York City area are hypertension, obesity, and diabetes, according to a study published online April 22 in the Journal of the American Medical Association.
FRIDAY, April 24, 2020 -- Malaria drugs touted by some as potential "game changers" against COVID-19 are actually too dangerous for general use, the U.S. Food and Drug Administration warned Americans on Friday.
FRIDAY, April 24, 2020 -- A review of vaping products has been delayed by the COVID-19 outbreak, the U.S. Food and Drug Administration announced Thursday.
FRIDAY, April 24, 2020 -- Inconclusive findings from a study investigating the antiviral drug remdesivir as a treatment for COVID-19 were posted to the World Health Organization website "prematurely," drug maker Gilead Sciences said Thursday.
FRIDAY, April 24, 2020 -- Mental health concerns top economic worries during the COVID-19 pandemic, according to the results of a survey released by the University of Phoenix.
FRIDAY, April 24, 2020 -- Greater vegetable intake before pregnancy is associated with better birth outcomes, according to a study published online April 13 in The American Journal of Clinical Nutrition.
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FRIDAY, April 24, 2020 -- The rate of infection with influenza, gastroenteritis, hepatitis, and pneumonia is increased before detection of malignant cancer, according to a study published online April 17 in Cancer Immunology Research.
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FRIDAY, April 24, 2020 -- In 2017 to 2018, 45.4 percent of adults had hypertension, with prevalence higher among men than women, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
FRIDAY, April 24, 2020 -- Measles, mumps, and rubella (MMR) vaccines and MMR vaccines with varicella are effective and safe, according to an updated review published online April 20 in the Cochrane Database of Systematic Reviews.
FRIDAY, April 24, 2020 -- Diabetes and/or uncontrolled hyperglycemia occur frequently among hospitalized patients with COVID-19 and are associated with worse outcomes, according to a study accepted for publication in the Journal of Diabetes Science and Technology.
FRIDAY, April 24, 2020 -- Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic, according to a study published online April 20 in ACR: Open Rheumatology.
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FRIDAY, April 24, 2020 -- During the COVID-19 outbreak in Hubei province in China, 22.6 percent of children in home confinement reported depressive symptoms, according to a research letter published online April 24 in JAMA Pediatrics.
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FRIDAY, April 24, 2020 -- The median duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is significantly longer in the respiratory samples of patients with severe versus mild disease, according to a study published online April 21 in The BMJ.
THURSDAY, April 23, 2020 -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can spread rapidly in homeless shelters, according to two studies published in the April 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
THURSDAY, April 23, 2020 -- In January to March 2020, there were more chemical exposures reported to the National Poison Data System than in the corresponding months of 2019 and 2018, according to research published in the April 20 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
THURSDAY, April 23, 2020 -- A plan to begin paying hospitals and doctors who treat uninsured COVID-19 patients was announced by U.S. Health and Human Services Secretary Alex Azar on Wednesday.
THURSDAY, April 23, 2020 -- A bill to create a "Health Force" to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.
THURSDAY, April 23, 2020 -- For patients with hypertension hospitalized with COVID-19 infections, angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) are not associated with the severity or mortality of COVID-19, according to a brief report published online April 23 in JAMA Cardiology.
THURSDAY, April 23, 2020 -- Most children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have mild respiratory symptoms or are asymptomatic, according to a review published online April 22 in JAMA Pediatrics.
THURSDAY, April 23, 2020 -- In older women, objectively measured visual impairment is associated with a twofold to more than fivefold increased risk for dementia, according to a study published online April 16 in JAMA Ophthalmology.
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THURSDAY, April 23, 2020 -- A mindful yoga intervention reduces testosterone levels in women with polycystic ovary syndrome (PCOS), according to a study published online April 14 in the Journal of the American Osteopathic Association.
THURSDAY, April 23, 2020 -- Clascoterone cream, 1 percent, appears to be safe and effective for the treatment of acne, according to a study published online April 22 in JAMA Dermatology.
THURSDAY, April 23, 2020 -- For patients hospitalized with mild/moderate COVID-19, lopinavir/ritonavir (LPV/r) or umifenovir (Arbidol) monotherapy offers little benefit, according to a study published online April 17 in Med.
THURSDAY, April 23, 2020 -- A registry has been created for reporting skin manifestations of COVID-19 following reports of patients presenting with skin conditions, including findings outlined in a letter to the editor published online March 26 in the Journal of the European Academy of Dermatology and Venereology.
THURSDAY, April 23, 2020 -- Chronic conditions, including asthma, mental health conditions, and obesity, are common among fatal cases of e-cigarette, or vaping, product use-associated lung injury (EVALI), according to a study published in the April 23 issue of the New England Journal of Medicine.
THURSDAY, April 23, 2020 -- Higher intake of manganese is associated with a lower type 2 diabetes risk among postmenopausal women, independent of known risk factors, according to a study published online April 15 in Diabetes Care.
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THURSDAY, April 23, 2020 -- Housing insecurity is tied to an increased risk for developing albuminuria, according to a study published March 31 in Kidney360.
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WEDNESDAY, April 22, 2020 -- Most emergency department admissions for firework-related injuries occur near Independence Day and New Year's Day, involve men and people younger than 18, and are caused by firecrackers and bottle rockets, according to a study published online April 9 in JAMA Ophthalmology.
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WEDNESDAY, April 22, 2020 -- There is no evidence that use of hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) reduces the risks for mechanical ventilation or death from any cause in patients hospitalized with COVID-19, according to a study that has not yet been peer reviewed and was posted online April 21 at medRxiv.org.
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WEDNESDAY, April 22, 2020 -- Focused eating habits with high processed meats and unhealthy snacking may be associated with increased dementia risk, according to a study published online April 22 in Neurology.
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WEDNESDAY, April 22, 2020 -- There is no proven drug treatment for COVID-19 patients, according to a panel of experts convened by the U.S. National Institute of Allergy and Infectious Diseases.
WEDNESDAY, April 22, 2020 -- A widely used rapid COVID-19 test can produce false negatives if a certain solution is used to move or store patients' samples, the test's maker said.
WEDNESDAY, April 22, 2020 -- According to the findings of two studies published online April 20 in the Journal of the American Heart Association, coronary artery disease (CAD) mortality rates have increased among women from rural areas, while social determinants of health (SDOH) increase the risk for 90-day mortality after heart failure hospitalization.
WEDNESDAY, April 22, 2020 -- For patients with COVID-19 who have ST-segment elevation, indicating potential acute myocardial infarction, there is considerable variability in presentation, and prognosis is poor, according to a letter to the editor published online April 17 in the New England Journal of Medicine.
WEDNESDAY, April 22, 2020 -- A model that includes data on clinical and genetic factors and circulating biomarkers may improve risk discrimination for pancreatic cancer, according to a study published online April 22 in Cancer Epidemiology, Biomarkers & Prevention.
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WEDNESDAY, April 22, 2020 -- Overall, 11.4 percent of adults had high total cholesterol during 2015 to 2018, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
WEDNESDAY, April 22, 2020 -- Altered heart rate variability (HRV) may be related to risk for incident diabetes in young Asian adults, according to a study published online April 16 in Diabetes Care.
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WEDNESDAY, April 22, 2020 -- For older adults, the risk for hospital admission due to respiratory disease (RD) is increased in association with living alone and social disengagement, according to a study published online April 21 in Thorax.
WEDNESDAY, April 22, 2020 -- There is a high frequency of obesity among patients admitted to intensive care for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online April 9 in Obesity.
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WEDNESDAY, April 22, 2020 -- While low blood levels of vitamin D are associated with osteoporotic fractures, the link is not causative, according to the results of an analysis published online April 7 in Clinical Chemistry.
WEDNESDAY, April 22, 2020 -- Women with inflammatory bowel disease (IBD) have lower pregnancy rates, and those with uncontrolled disease are at increased risk for adverse outcomes, according to a study published online April 7 in Alimentary Pharmacology and Therapeutics.
TUESDAY, April 21, 2020 -- COVID-19 is not associated with the symptoms typically associated with a viral cold or allergies, such as nasal blockage or mucus production, according to a review published online April 10 in Laryngoscope Investigative Otolaryngology.
TUESDAY, April 21, 2020 -- The U.S. Preventive Services Task Force (USPSTF) concludes that there is currently insufficient evidence to evaluate the balance of benefits and harms of screening children and adolescents for high blood pressure. These findings form the basis of a draft recommendation statement, published April 21 by the USPSTF.
TUESDAY, April 21, 2020 -- A new position paper, published online April 15 in The Lancet Psychiatry, highlights the mental health consequences of COVID-19 management.
TUESDAY, April 21, 2020 -- The U.S. Food and Drug Administration has approved emergency use of the first COVID-19 test that enables patients to take samples at home.
TUESDAY, April 21, 2020 -- An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.
TUESDAY, April 21, 2020 -- About 176,190 children nationwide were estimated to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by April 6, 2020, according to a study published online April 16 in the Journal of Public Health Management & Practice.
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TUESDAY, April 21, 2020 -- Most community-dwelling older adults with newly identified dementia die or are admitted to a long-term care home within five years, according to a study published online April 20 in CMAJ, the journal of the Canadian Medical Association.
TUESDAY, April 21, 2020 -- Expanding COVID-19 symptom screening criteria to include myalgias and chills could identify more health care personnel (HCP) with the illness, according to a research letter published online April 17 in the Journal of the American Medical Association.
TUESDAY, April 21, 2020 -- Excess asymptomatic thyroid cancer in Fire Department World Trade Center (WTC)-exposed rescue/recovery workers is apparently attributable to the identification of occult lesions during medical surveillance, according to a study published online April 20 in JAMA Internal Medicine.
TUESDAY, April 21, 2020 -- Greater screen exposure and less interactive play between caregivers and children early in life is associated with autism spectrum disorder (ASD)-like symptoms at age 2 years, according to a study published online April 20 in JAMA Pediatrics.
TUESDAY, April 21, 2020 -- Few primary care physicians report interest in treating patients with opioid use disorder (OUD), according to a research letter published online April 21 in the Annals of Internal Medicine.
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TUESDAY, April 21, 2020 -- About 20 percent of specimens positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are positive for other respiratory pathogens, according to a research letter published online April 15 in the Journal of the American Medical Association.
TUESDAY, April 21, 2020 -- While quitting smoking during the first trimester slightly decreases the risk for low birth weight in newborns, any duration of maternal smoking during pregnancy is associated with low birth weight and abnormal body proportions, according to a study recently published in BMJ Open.
TUESDAY, April 21, 2020 -- For people with substance use disorders, combining HIV and hepatitis C virus (HCV) testing and providing immediate test results may increase the number of people who are aware of their infection status, according to a study published in the May issue of Medical Care.
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MONDAY, April 20, 2020 -- Cervical cancer screening rates (CCS-Rs) in Japan were significantly lower in the years following the devastating Great East Japan Earthquake of 2011, according to a study recently published online in PLOS ONE.
MONDAY, April 20, 2020 -- Retirement of coal-fired power plants or installation of stricter emissions controls is associated with better asthma-related outcomes, according to a study published online April 13 in Nature Energy.
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MONDAY, April 20, 2020 -- The first COVID-19 tests in the United States were ineffective due to poor laboratory practices at the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration said.
MONDAY, April 20, 2020 -- Public health measures implemented to suppress local transmission of COVID-19 in Hong Kong were associated with reduced transmission of COVID-19 and influenza, according to a study published online April 17 in The Lancet Public Health.
MONDAY, April 20, 2020 -- In an American Academy of Pediatrics (AAP) policy statement, published online April 20 in Pediatrics, recommendations are presented for the care of newborn infants immediately after birth and in the transition and subsequent period after home birth.
MONDAY, April 20, 2020 -- Maternal hypertensive pregnancy disorders are associated with increased risk in offspring for any childhood mental disorder, according to a study published online April 20 in Hypertension.
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MONDAY, April 20, 2020 -- About one in four cases of colorectal cancer (CRC) in patients aged 40 to 49 years meet family history-based criteria for early screening, according to a study published online April 20 in Cancer.
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MONDAY, April 20, 2020 -- Diabetes may contribute to more severe symptoms, rapid progression, and poorer prognosis in patients infected with COVID-19, according to a study published online March 31 in Diabetes Metabolism Research and Reviews.
MONDAY, April 20, 2020 -- The economic benefits of lives saved through social distancing substantially outweigh the value of the projected losses to the U.S. economy, according to a study to be published in a forthcoming issue of the Journal of Benefit-Cost Analysis.
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MONDAY, April 20, 2020 -- Obesity in children is associated with an increased risk for premature mortality in young adulthood and with an increased risk for anxiety and depression, according to two studies published online in March in PLOS Medicine and BMC Medicine.
MONDAY, April 20, 2020 -- The number of veterans being diagnosed with attention-deficit/hyperactivity disorder (ADHD) is increasing, according to a study published in the March issue of Medical Care.
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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 13 to 17, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
FRIDAY, April 17, 2020 -- Transmission of coronavirus disease 2019 (COVID-19) to health care personnel (HCP) is explored in two studies published in the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
FRIDAY, April 17, 2020 -- In Iceland, the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was stable through 20 days of screening, according to a study published online April 14 in the New England Journal of Medicine.
FRIDAY, April 17, 2020 -- Asthma is not among the top 10 chronic health problems in people who have died from coronavirus disease 2019 (COVID-19) in New York state, even though many health experts have warned that people with asthma are at increased risk for severe illness if they get COVID-19.
FRIDAY, April 17, 2020 -- In rapid guidelines issued by the Infectious Diseases Society of America (IDSA), recommendations are presented for the treatment and management of coronavirus disease 2019 (COVID-19).
FRIDAY, April 17, 2020 -- Most patients presenting to urgent care centers with confirmed coronavirus disease 2019 (COVID-19) have normal or mildly abnormal findings on chest X-rays (CXRs), according to a study published online April 14 in the Journal of Urgent Care Medicine.
FRIDAY, April 17, 2020 -- Juul sales recovered within weeks following a dip after the company withdrew some flavored products from stores, even surpassing sales before the withdraw, according to a study published online April 16 in the American Journal of Public Health.
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FRIDAY, April 17, 2020 -- Higher nighttime blood pressure may exacerbate the detrimental effects of hypertension on cerebrovascular health and cognitive abilities among middle-aged individuals, according to a study published online April 15 in Neurology.
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FRIDAY, April 17, 2020 -- Women with lower ovarian reserve do not experience differences in adiposity and glucose metabolism during their reproductive life span compared with women with high ovarian reserve, according to a study published online April 13 in Menopause.
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FRIDAY, April 17, 2020 -- The use of probiotics as an adjunct therapy may help in the management of acne vulgaris, according to a review published online April 7 in Dermatologic Therapy.
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FRIDAY, April 17, 2020 -- Mindfulness-based stress reduction training is associated with robust improvements in gastrointestinal symptoms for patients with irritable bowel syndrome (IBS), according to a study published online April 7 in Neurogastroenterology & Motility.
FRIDAY, April 17, 2020 -- Consuming foods high in vitamin D may have heart-protective effects, according to a Greek study published online April 7 in the Journal of Human Nutrition and Dietetics.
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FRIDAY, April 17, 2020 -- From 2007 to 2016, the incidence of cancers of the oral cavity and pharynx combined increased, according to research published in the April 17 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
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FRIDAY, April 17, 2020 -- Active cigarette smokers and individuals with chronic obstructive pulmonary disease (COPD) have up-regulation of angiotensin converting enzyme II (ACE-2) expression in the lower airways, which could explain the increased risk for severe COVID-19 in these subpopulations, according to a study published online April 8 in the European Respiratory Journal.
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THURSDAY, April 16, 2020 -- There has been such a drop in demand for coronavirus disease 2019 (COVID-19) tests at private labs in the United States that they have "considerable" unused capacity and can test more patients with less severe symptoms, the American Clinical Laboratory Association (ACLA) says.
THURSDAY, April 16, 2020 -- The U.S. Food and Drug Administration is asking Americans who have recovered from coronavirus disease 2019 (COVID-19) to donate their blood plasma to help fight the pandemic.
THURSDAY, April 16, 2020 -- Researchers say they have developed a low-cost swab test that can diagnose coronavirus disease 2019 (COVID-19) infections in about 45 minutes.
THURSDAY, April 16, 2020 -- Recurrent winter outbreaks of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are projected to occur after the initial pandemic wave, according to a study published online April 14 in Science.
THURSDAY, April 16, 2020 -- Black individuals' higher cumulative blood pressure (BP) levels may influence racial differences in cognitive decline, according to a study published online April 13 in JAMA Neurology.
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THURSDAY, April 16, 2020 -- Among new mothers living in poverty, the Affordable Care Act (ACA) Medicaid expansion was associated with a reduction in uninsurance and increased Medicaid coverage, according to a study published online April 15 in Pediatrics.
THURSDAY, April 16, 2020 -- Having normal body weight is crucial in the prevention of type 2 diabetes, regardless of genetic predisposition, according to a study published online April 15 in Diabetologia.
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THURSDAY, April 16, 2020 -- The prevalence of antinuclear antibodies (ANA) in the United States has increased considerably between 1988 and 2012, according to a study published online April 7 in Arthritis & Rheumatology.
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WEDNESDAY, April 15, 2020 -- In the era of coronavirus disease 2019 (COVID-19), compliance with self-isolation is influenced by compensation, with very high compliance seen when compensation for lost wages is assured, according to a report published online April 9 in Health Affairs.
WEDNESDAY, April 15, 2020 -- Risk for out-of-hospital cardiac arrest increases by 70 percent with exposure to heavy wildfire smoke, according to a study published online April 15 in the Journal of the American Heart Association.
WEDNESDAY, April 15, 2020 -- People who receive additional treatment following medically managed opioid withdrawal have reduced mortality compared with those who do not receive treatment, according to a study recently published in Addiction.
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WEDNESDAY, April 15, 2020 -- Obesity is associated with admission to the hospital for coronavirus disease 2019 (COVID-19) patients, according to a study published online April 9 in Clinical Infectious Diseases and a study not yet peer reviewed and posted on medRxiv.org.
WEDNESDAY, April 15, 2020 -- Many individuals at greater risk for coronavirus disease 2019 (COVID-19) complications did not believe the virus would affect them at the beginning of Chicago's outbreak, according to a study published online April 9 in the Annals of Internal Medicine.
WEDNESDAY, April 15, 2020 -- Considerable severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) contamination of air and object surfaces is reported in intensive care units (ICUs) and general coronavirus disease 2019 (COVID-19) wards (GW), according to a study published online April 10 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.
WEDNESDAY, April 15, 2020 -- Five causes of death accounted for 89.5 percent of fetal deaths reported during 2015 to 2017, according to a report published April 15 in the U.S. Centers for Disease Control and Prevention National Vital Statistics Report.
WEDNESDAY, April 15, 2020 -- Multifaceted public health interventions improved control of the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, according to a study published online April 10 in the Journal of the American Medical Association.
WEDNESDAY, April 15, 2020 -- Closer adherence to the alternative Mediterranean diet (aMED) is associated with a reduced risk for cognitive decline, but not with slower decline in cognitive function, according to a study published online April 13 in Alzheimer's & Dementia.
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WEDNESDAY, April 15, 2020 -- The overall prevalence of self-reported hypertension is 32.4 percent, with prevalence higher among men than women and among blacks, according to research published in the April 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
WEDNESDAY, April 15, 2020 -- Common coronaviruses circulate seasonally, according to a study published online April 4 in the Journal of Infectious Diseases.
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WEDNESDAY, April 15, 2020 -- The rates of pregnancy-related acute kidney injury (AKI) hospitalizations increased during the last decade, according to a study published in the March issue of the American Journal of Nephrology.
TUESDAY, April 14, 2020 -- Smell and taste impairment are strongly associated with coronavirus disease 2019 (COVID-19) positivity, according to a study published online April 12 in the International Forum of Allergy & Rhinology.
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TUESDAY, April 14, 2020 -- Quarantine is effective for reducing the number of people infected and deaths from coronavirus disease 2019 (COVID-19), according to a review published online April 8 in the Cochrane Database of Systematic Reviews.
TUESDAY, April 14, 2020 -- Community mobility in four metropolitan areas decreased with the introduction of public policy measures supporting social distancing, which could help slow the spread of coronavirus disease 2019 (COVID-19), according to research published in the April 13 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
TUESDAY, April 14, 2020 -- Health insurers and Medicaid must provide free coverage for tests to detect coronavirus 2019 (COVID-19) antibodies in people who have been infected, the federal government says.
TUESDAY, April 14, 2020 -- The first saliva test for coronavirus 2019 (COVID-19) was approved Monday by the U.S. Food and Drug Administration.
TUESDAY, April 14, 2020 -- Hepatitis C screening is recommended for all adults and for all pregnant women, except where the prevalence is below 0.1 percent; meanwhile, the annual rate of reported acute hepatitis C cases increased to 1.2 per 100,000 population in 2018, according to recommendations and a report published in the April 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
TUESDAY, April 14, 2020 -- Women born by cesarean delivery may have a higher risk for being obese and developing type 2 diabetes during adult life than women born by vaginal delivery, according to a study published online April 13 in JAMA Network Open.
TUESDAY, April 14, 2020 -- Use of medical masks, such as surgical or procedural masks, does not increase the risk for viral infection or respiratory illness, and their use may serve as a protective measure in instances of N95 respirator shortages, according to the results of a meta-analysis published online April 4 in Influenza and Other Respiratory Viruses.
TUESDAY, April 14, 2020 -- The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is detectable in the feces of COVID-19 patients and remains even after negative conversion in pharyngeal swabs, according to a study published online April 3 in the Journal of Medical Virology.
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TUESDAY, April 14, 2020 -- Interventions implemented in China interrupted coronavirus disease 2019 (COVID-19) transmission in all areas outside of Hubei, and low transmissibility can be maintained by monitoring the instantaneous effective reproduction number (Rt), according to a study published online April 8 in The Lancet.
TUESDAY, April 14, 2020 -- The COVID-19 Hospital Impact Model (CHIME), a publicly available tool, can help hospitals predict the timing of saturated capacity, according to a report published online April 7 in the Annals of Internal Medicine.
TUESDAY, April 14, 2020 -- Preschool children with a body mass index (BMI) in the overweight or obese range have an increased incidence of bone fractures in childhood compared with preschool children of normal weight, according to a study published online April 7 in the Journal of Bone and Mineral Research.
MONDAY, April 13, 2020 -- Hydroxychloroquine usage is expanding globally to treat coronavirus 2019 (COVID-19), although plasma from recovered patients is perceived as more effective than hydroxychloroquine, according to a report released by Sermo.
MONDAY, April 13, 2020 -- Adults who stopped working during coronavirus 2019 (COVID-19)-related lockdowns in China report worse mental and physical health, according to a study published online April 4 in Psychiatry Research.
MONDAY, April 13, 2020 -- Large-scale studies of tests to check for antibodies to coronavirus 2019 (COVID-19) are underway in California. The findings from this research could help the United States develop strategies to get people back to work and restart the economy.
MONDAY, April 13, 2020 -- A study of chloroquine in coronavirus 2019 (COVID-19) patients was halted due to potentially deadly side effects.
MONDAY, April 13, 2020 -- The rates of appropriate electronic consultations (e-consults) are high across specialties, according to a study published online April 14 in the Annals of Internal Medicine.
MONDAY, April 13, 2020 -- There is variation in the cumulative incidence of coronavirus disease 2019 (COVID-19) across jurisdictions in the United States, according to research published in the April 10 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
MONDAY, April 13, 2020 -- In a multinational consensus statement from the Fleischner Society, published online April 7 in Radiology, recommendations are presented for use of imaging in patients with coronavirus disease 2019 (COVID-19).
MONDAY, April 13, 2020 -- Most home blood pressure (BP) devices available online are nonvalidated, and they are sold at a lower cost than validated ones, according to a study published online April 13 in Hypertension.
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MONDAY, April 13, 2020 -- Digital breast tomosynthesis (DBT) is associated with an overall decrease in recall rate and an increase in cancer detection rate, according to a study published online March 30 in JAMA Network Open.
MONDAY, April 13, 2020 -- National, race-based differences in prostate cancer survival are due to regional variation, even for low-risk prostate cancer, according to a study published online March 31 in JAMA Network Open.
MONDAY, April 13, 2020 -- In an initial guidance document issued by the American Academy of Pediatrics, recommendations are presented for the management of infants born to mothers with suspected or confirmed coronavirus disease 2019 (COVID-19).
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 6 to 10, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
FRIDAY, April 10, 2020 -- One index patient with COVID-19 and only mild symptoms attended two family gatherings and likely triggered a chain of transmission that included 15 other confirmed and probable cases with three deaths, according to research published in the April 8 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
FRIDAY, April 10, 2020 -- Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.
FRIDAY, April 10, 2020 -- Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.
FRIDAY, April 10, 2020 -- The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.
FRIDAY, April 10, 2020 -- Even in middle age, women can make lifestyle modifications that can substantially lower their stroke risk, according to a study published online April 9 in Stroke.
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FRIDAY, April 10, 2020 -- Novel coronavirus (COVID-19)-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.
FRIDAY, April 10, 2020 -- Compared with adults, symptoms of COVID-19 in newborn babies are milder and outcomes are less severe, according to a research letter published online April 8 in the European Respiratory Journal.
FRIDAY, April 10, 2020 -- Non-medically trained health care workers caring for patients with coronavirus disease 2019 (COVID-19) have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.
FRIDAY, April 10, 2020 -- Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.
FRIDAY, April 10, 2020 -- There is limited, very low-certainty evidence of a protective effect for nocturnal supervision against sudden unexpected death in epilepsy (SUDEP), according to a report published online April 2 in the Cochrane Database of Systematic Reviews.
FRIDAY, April 10, 2020 -- The prevalence rates of smoking and cessation in adulthood are associated with levels of childhood smoking intensity, according to a study published in the April 9 issue of the Journal of the American Heart Association.
FRIDAY, April 10, 2020 -- The risk for incident depression increases with body mass index (BMI) among overweight and obese patients, according to a study published online April 8 in Obesity.
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FRIDAY, April 10, 2020 -- There are sex- and gender-specific differences related to clinical characteristics and quality-of-life (QoL) measures in patients with psoriasis, according to a study published online March 14 in Clinical and Experimental Dermatology.
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FRIDAY, April 10, 2020 -- Adults diagnosed with type 2 diabetes between the ages of 21 and 44 years have higher initial hemoglobin A1c (HbA1c) levels and a lower likelihood of achieving glycemic control within one year of diagnosis versus patients diagnosed in middle age, according to a study recently published in Diabetes Care.
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THURSDAY, April 9, 2020 -- Doctors at the University of Alabama at Birmingham (UAB) are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus (COVID-19) who have severely damaged lungs.
THURSDAY, April 9, 2020 -- Another clinical trial of an experimental vaccine for the novel coronavirus 2019 (COVID-19) has been launched by U.S. researchers.
THURSDAY, April 9, 2020 -- A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus (COVID-19), the U.S. Food and Drug Administration says.
THURSDAY, April 9, 2020 -- A clinical trial to assess the antimalarial drug hydroxychloroquine as a treatment for adults with the novel coronavirus (COVID-19) is now underway, the U.S. National Institutes of Health said Thursday.
THURSDAY, April 9, 2020 -- The novel coronavirus (COVID-19) has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.
THURSDAY, April 9, 2020 -- In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019 (COVID-19).
THURSDAY, April 9, 2020 -- Parental mental illness is associated with an increased risk for injuries among offspring, especially during the first year of the child's life, according to a study published online April 8 in The BMJ.
THURSDAY, April 9, 2020 -- Stage at diagnosis, treatment, and survival differ by race and ethnicity for patients with one of the nine leading cancers, according to a study published online April 8 in JAMA Network Open.
THURSDAY, April 9, 2020 -- Researchers have identified the most common clinical characteristics among 109 patients out of 1,017 with confirmed novel coronavirus (COVID-19) pneumonia who died of COVID-19-related pneumonia in Wuhan, China; their findings were published online April 7 in the Annals of the American Thoracic Society.
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THURSDAY, April 8, 2020 -- Exposure to air pollution may have adverse effects on cognitive aging and brain health in older adults, according to a study published online April 8 in Neurology.
THURSDAY, April 9, 2020 -- Probiotic treatment with dead bacteria is better than placebo at alleviating symptoms of irritable bowel syndrome (IBS), according to a study published online April 8 in The Lancet Gastroenterology & Hepatology.
THURSDAY, April 9, 2020 -- Stomach acid suppression medications increase the odds of intestinal colonization with multidrug-resistant microorganisms (MDROs), according to a review and meta-analysis recently published in JAMA Internal Medicine.
THURSDAY, April 9, 2020 -- For patients with osteoarthritis of the knee, those undergoing physical therapy have less pain and functional disability at one year compared with those who receive an intraarticular glucocorticoid injection, according to a study published in the April 9 issue of the New England Journal of Medicine.
WEDNESDAY, April 8, 2020 -- Physical activity is linked to fewer depressive symptoms, higher satisfaction with life, and higher positive affectivity in menopausal women, according to a study published in the April issue of Menopause.
WEDNESDAY, April 8, 2020 -- The novel coronavirus (COVID-19) death rate in New York City is two times higher among men than among women, and men also have higher rates of infection and hospitalization, new data show.
WEDNESDAY, April 8, 2020 -- Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus (COVID-19) are no longer available on the U.S. Centers for Disease Control and Prevention website.
WEDNESDAY, April 8, 2020 -- Children with coronavirus disease 2019 (COVID-19) have symptoms of fever, cough, or shortness of breath less often than adults with the disease, according to research published in the April 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
WEDNESDAY, April 8, 2020 -- Suicide rates increased 35 percent from 1999 through 2018, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
WEDNESDAY, April 8, 2020 -- Patients with celiac disease have a small but statistically significantly increased mortality risk compared with controls, according to a study published in the April 7 issue of the Journal of the American Medical Association.
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WEDNESDAY, April 8, 2020 -- For patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.
WEDNESDAY, April 8, 2020 -- Women mainly use fertility apps for fertility and reproductive health tracking, pregnancy planning, and pregnancy prevention, according to a review published online April 6 in BMJ Sexual & Reproductive Health.
WEDNESDAY, April 8, 2020 -- Heavy drinkers who continue drinking into old age have significantly larger waistlines and increased stroke risk, according to a study published online March 31 in Addiction.
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WEDNESDAY, April 8, 2020 -- A claims-based frailty index can improve current Medicare cost prediction for patients with different levels of frailty, according to a study published online April 7 in the Annals of Internal Medicine.
WEDNESDAY, April 8, 2020 -- Children diagnosed with COVID-19 have a milder disease course and better prognoses than adults, according to a review published online March 23 in Acta Paediatrica.
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WEDNESDAY, April 8, 2020 -- Mothers with a body mass index (BMI) of 25 kg/m² and greater are more likely to see behavioral problems and psychiatric symptoms in their children, according to a study recently published in The Journal of Pediatrics.
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TUESDAY, April 7, 2020 -- The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.
TUESDAY, April 7, 2020 -- Serious concerns are associated with coronavirus disease 2019 (COVID-19), and many individuals are preparing by washing hands and self-isolating, according to a research letter published online April 7 in JAMA Internal Medicine.
TUESDAY, April 7, 2020 -- The U.S. Preventive Services Task Force (USPSTF) recommends against screening for bacterial vaginosis in pregnant women not at increased preterm delivery risk, and more research is needed for those at increased risk. These findings form the basis of a final recommendation statement published in the April 7 issue of the Journal of the American Medical Association.
TUESDAY, April 7, 2020 -- When hypothetical stay-at-home orders in response to COVID-19 are extended longer than expected, people become less willing to increase self-isolation efforts, according to a working paper released by the National Bureau of Economic Research.
TUESDAY, April 7, 2020 -- Most fatal cases of coronavirus disease 2019 (COVID-19) occur in men aged older than 50 years with noncommunicable chronic diseases, according to a study published online April 3 in the American Journal of Respiratory and Critical Care Medicine.
TUESDAY, April 7, 2020 -- Preliminary data regarding outcomes for pediatric patients with inflammatory bowel disease (IBD) during the coronavirus disease 2019 (COVID-19) outbreak are reassuring, according to research published online March 31 in the Journal of Pediatric Gastroenterology and Nutrition.
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TUESDAY, April 7, 2020 -- Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 (COVID-19) pandemic, according to a study published online April 3 in The Lancet Public Health.
TUESDAY, April 7, 2020 -- Compared with children who are naturally conceived, children who are conceived via assisted reproductive techniques (ART) may be at increased risk for mortality during their first year of life, according to a study published in the March issue of Fertility and Sterility.
TUESDAY, April 7, 2020 -- Genetic testing is not better at predicting coronary heart disease risk compared with conventional risk factors, according to a study published in a recent issue of the Journal of the American Medical Association.
TUESDAY, April 7, 2020 -- Baseline modifiable (mod) electronic cigarette device users smoke more cigarettes at one-year follow-up than vape pen users, according to a study published online April 6 in Pediatrics.
TUESDAY, April 7, 2020 -- An initiative to add social workers to rural primary care teams increases social work encounters among veterans and reduces hospital admissions and emergency department visits among high-risk patients, according to a report published in the April issue of Health Affairs.
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TUESDAY, April 7, 2020 -- In a special article published online April 1 in Advances in Radiation Oncology, a framework is laid out for the management of radiotherapy for prostate cancer patients during the coronavirus disease 2019 (COVID-19) pandemic.
MONDAY, April 6, 2020 -- For patients with stable coronary disease and moderate-to-severe ischemia, an initial invasive strategy does not improve outcomes, but it may improve angina-related health status, according to two studies published online March 30 in the New England Journal of Medicine.
MONDAY, April 6, 2020 -- Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.
MONDAY, April 6, 2020 -- According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.
MONDAY, April 6, 2020 -- Rapid sentinel surveillance can help monitor the epidemiology of coronavirus disease 2019 (COVID-19), according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
MONDAY, April 6, 2020 -- Factors associated with coronavirus disease 2019 (COVID-19) progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.
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MONDAY, April 6, 2020 -- Hydroxychloroquine (HCQ) can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019 (COVID-19), according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.
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MONDAY, April 6, 2020 -- High total fiber consumption is associated with a reduced risk for breast cancer, according to a review and meta-analysis published online April 6 in Cancer.
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MONDAY, April 6, 2020 -- Older age is associated with an increased risk for bacteremia in hospitalized patients with inflammatory bowel disease (IBD), according to a study published in the March issue of the United European Gastroenterology Journal.
MONDAY, April 6, 2020 -- The incidence of heart attacks is decreasing, but the trend seems to have slowed in women, according to a study recently published in Circulation.
MONDAY, April 6, 2020 -- First-time mothers with preeclampsia are at a higher risk for adverse cardiovascular outcomes, including myocardial infarction, stroke, and cardiovascular death, according to a study recently published in the Journal of Women's Health.
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Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.
FRIDAY, April 3, 2020 -- A number of institutions this week announced their participation in an international clinical drug trial evaluating the safety and efficacy of remdesivir in hospitalized patients with the novel coronavirus 2019 (COVID-19).
FRIDAY, April 3, 2020 -- Microneedle array (MNA) delivery of trimeric coronavirus spike (S) protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to research published online April 2 in EBioMedicine.
FRIDAY, April 3, 2020 -- Presymptomatic transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been observed in epidemiological clusters in Singapore, with transmission occurring one to three days before symptom onset, according to research published in the April 1 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
FRIDAY, April 3, 2020 -- Modeling suggests that in Italy, the number of coronavirus disease 2019 (COVID-19) intensive care unit (ICU) patients will continue increasing into April, according to a report published April 1 by the European Society of Anaesthesiology.
FRIDAY, April 3, 2020 -- Chronic obstructive pulmonary disease (COPD) is an independent risk factor for lung cancer incidence, regardless of smoking status, according to a study published online April 2 in Thorax.
FRIDAY, April 3, 2020 -- Deep early remission of Crohn disease is associated with a significant decrease in long-term adverse effects, according to a study published online March 26 in Gastroenterology.
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FRIDAY, April 3, 2020 -- Rates of autism spectrum disorders (ASD) are declining among wealthy whites in California while escalating among poor and minority children, according to a study published online March 19 in the Journal of Autism and Developmental Disorders.
FRIDAY, April 3, 2020 -- Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol (THC) and cannabidiol (CBD) than needed for chronic pain relief, according to a study published online March 26 in PLOS ONE.
FRIDAY, April 3, 2020 -- Greater alcohol consumption is associated with lower serum levels of bone formation markers among patients living with HIV and substance use disorder, according to a study published online March 2 in Alcoholism: Clinical & Experimental Research.
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FRIDAY, April 3, 2020 -- America is in urgent need of blood donations during the COVID-19 pandemic, so the U.S. Food and Drug Administration said Thursday it will relax donor restrictions placed on gay and bisexual men and others.
FRIDAY, April 3, 2020 -- Gastrointestinal symptoms are common in patients with coronavirus disease 2019 (COVID-19), with increased prevalence seen in the later stages of the epidemic in China, according to a review published online March 29 in Alimentary Pharmacology & Therapeutics.
THURSDAY, April 2, 2020 -- Following implementation of the Affordable Care Act (ACA), unemployed workers were less likely to be uninsured, and uninsurance rates decreased more in states with Medicaid expansion, according to a report from the Urban Institute and the Robert Wood Johnson Foundation.
THURSDAY, April 2, 2020 -- Certain patient and presentation factors increase the likelihood of a missed appendicitis diagnosis in the emergency department, according to a study published online March 9 in JAMA Network Open.
THURSDAY, April 2, 2020 -- Disruptions in insurance coverage around the time of pregnancy disproportionately affect indigenous, Hispanic, and black non-Hispanic women, according to a study published in the April issue of Obstetrics & Gynecology.
THURSDAY, April 2, 2020 -- Proton pump inhibitors (PPIs) taken for acid reflux may lead to an increased risk for fractures in children and adolescents, according to a study published online March 12 in the Journal of Pediatric Gastroenterology and Nutrition.
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THURSDAY, April 2, 2020 -- Transmission control measures implemented in Wuhan were associated with a delay in epidemic growth during the first 50 days of the coronavirus disease 2019 (COVID-19) epidemic in China, according to a study published online March 31 in Science.
THURSDAY, April 2, 2020 -- Most macronutrient diets result in modest weight loss and improvements in cardiovascular risk factors over six months, according to a review and meta-analysis published online April 1 in The BMJ.
THURSDAY, April 2, 2020 -- From 2011 to 2017, there was a decrease in the estimated national burden of Clostridium difficile infection, according to a study published in the April 2 issue of the New England Journal of Medicine.
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THURSDAY, April 2, 2020 -- Endoscopy within six hours versus six to 24 hours after consultation is not associated with lower 30-day mortality in patients with acute upper gastrointestinal bleeding who are at high risk for further bleeding or death, according to a study published in the April 2 issue of the New England Journal of Medicine.
THURSDAY, April 2, 2020 -- Patients with left ventricular assist devices (LVADs) who live remotely can be successfully managed with specialized training and cooperation between local physicians and specialty medical centers, according to a study published in the April issue of JACC: Heart Failure.
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THURSDAY, April 2, 2020 -- Patients with coronavirus disease 2019 (COVID-19) with longer time from symptom onset to diagnosis have higher computed tomography (CT) scores and longer time to disease resolution, according to a study published online March 30 in the American Journal of Roentgenology.
WEDNESDAY, April 1, 2020 -- For the first time since February, imported N95 medical masks are arriving in the United States, but they are not nearly enough to meet demand as COVID-19 cases climb.
WEDNESDAY, April 1, 2020 -- All versions of the heartburn drug Zantac (ranitidine) have been pulled from the U.S. market due to possible contamination with a probable human carcinogen, the U.S. Food and Drug Administration said Wednesday.
WEDNESDAY, April 1, 2020 -- Up to half of people who test positive for the new coronavirus do not have symptoms, results from Iceland show.
WEDNESDAY, April 1, 2020 -- Telephone-based cognitive behavioral therapy (T-CBT) seems to be an effective intervention for depression in Parkinson disease (PD), outperforming treatment-as-usual (TAU) on all depression, anxiety, and quality-of-life measures, according to a study published online April 1 in Neurology.
WEDNESDAY, April 1, 2020 -- In the United States, individuals with underlying health conditions have an increased risk for severe coronavirus disease 2019 (COVID-19), according to research published in the March 31 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
WEDNESDAY, April 1, 2020 -- About one-third of patients with coronavirus disease 2019 (COVID-19) have ocular abnormalities, according to a brief report published online March 31 in JAMA Ophthalmology.
WEDNESDAY, April 1, 2020 -- The White House coronavirus task force delivered a tough statistic to Americans late Tuesday, warning that the U.S. death toll from COVID-19 could climb to 240,000, even with social distancing policies in place.
WEDNESDAY, April 1, 2020 -- Liraglutide plus lifestyle therapy results in a significantly greater reduction in body mass index (BMI) standard-deviation score than placebo among adolescents with obesity, according to a study published online March 31 in the New England Journal of Medicine to coincide with the virtual meeting of The Endocrine Society, held from March 28 to 31.
WEDNESDAY, April 1, 2020 -- There are four developmental patterns of peer victimization across childhood, and family vulnerabilities are associated with development of distinct trajectories, according to a study published online April 1 in Pediatrics.
WEDNESDAY, April 1, 2020 -- Patients with mild coronavirus disease 2019 (COVID-19) can present with digestive symptoms, sometimes without concurrent fever, according to a study published online March 30 in the American Journal of Gastroenterology.
WEDNESDAY, April 1, 2020 -- Vitamin D deficiencies are associated with a lower likelihood of older patients regaining independent walking ability following hip fracture surgery, according to a study recently published in the American Journal of Clinical Nutrition.
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WEDNESDAY, April 1, 2020 -- Older patients taking five or more medications in the six months before intravenous (IV) chemotherapy are at higher risk for postchemotherapy inpatient hospitalizations, according to a study published online March 18 in the Journal of Geriatric Oncology.
WEDNESDAY, April 1, 2020 -- Some patients with coronavirus disease 2019 (COVID-19) remain positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in sputum or feces after pharyngeal samples become negative, according to a research letter published online March 30 in the Annals of Internal Medicine.
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Posted: May 2020