Remdesivir: The drug that could help virus patients

AFP|
No vaccine
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No vaccine

With the coronavirus sinking its claws deeper and deeper into the world, and with no vaccine in sight till at least a year, the best way to deal with COVID-19 is to use stop gap measures to relieve pain.

AP
Drug trials
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Drug trials

Remdesivir has become the first drug with proven benefits against COVID-19, with a major US-led trial concluding as much.

Reuters
Ebola
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Ebola

The drug was originally engineered to treat Ebola - by US pharmaceutical Gilead Sciences - but was not as successful in beating the disease as the other medicines it was up against, eventually getting discontinued, because it did not boost survival rates.

Reuters
Second coming
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Second coming

In February, the drug was brought back, to test its effectiveness against SARS-CoV-2, because it had shown promise in animal testing against SARS and MERS, which are from the same coronavirus family.

AFP
How it works
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How it works

Remdesivir is an antiviral that acts as a nucleotide analog, in essence, sneaking into the virus's genome instead of adenosine (a building block in cellular replication), which in turn short circuits the process.

AP
Respiratory relief
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Respiratory relief

In a trial with 1,000 subjects, it was found that patients on the drug had a 31% faster time to recovery. In essence, hospitalized COVID-19 patients with respiratory distress got better quicker than those on a placebo.

AP
A start
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A start

It's not a miracle cure, but it is a step in the right direction, proof that there is light at the end of this specific tunnel and it will eventually lead to a better, more effective drug.

AP

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