Firstview Insight's Obstructive Sleep Apnea Pricing Market Access and Landscape 2019 provides country specific insights in order to estimate market potential for Obstructive Sleep Apnea based on the pricing and reimbursement scenario and perceived value drivers in different market archetypes. It gives a detailed picture of the disease landscape and unmet needs of different stakeholders existing in the current treatment paradigmThus it enables to identify and leverage on the commercial opportunities spanning across different lines of therapy. The report incorporates detailed analysis of the market development drivers as well as the preventing factors. The scope of the report covers an extensive estimation pertaining to the winning essentials and participant schemes through a presentation of the segmentation of market in the Pricing Market Access landscape.
Obstructive sleep apnea OSA is the most common type of sleep apnea and is characterised by repeated episodes of complete or partial obstructions of the upper airway during sleep, despite the effort to breathe, and is usually associated with a reduction in blood oxygen saturation. In the Obstructive Sleep ApneaHypopnea Syndrome, the episodes of decreased breathing are called hypopnea and its definition requires a 30% drop in flow for 10 seconds or longer, associated with 3% oxygen desaturation. The episodes of breathing cessations are called apneas literally, without breath and to be defined, a 90% drop in flow for 10 seconds or longer must be assessed and associated with 3% oxygen desaturation, or an arousal OSA is commonly accompanied with snoring. The terms obstructive sleep apnea syndrome or obstructive sleep apneahypopnea syndrome are used to refer to OSA when it is associated with symptoms during the daytime e.g. excessive daytime sleepiness, decreased cognitive functions. Symptoms may be present for years or even decades without identification, during which time the individual may become conditioned to the daytime sleepiness and fatigue associated with significant levels of sleep disturbance. Individuals who generally sleep alone are often unaware of the condition, without a regular bedpartner to notice and make them aware of the signs.
As the muscle tone of the body ordinarily relaxes during sleep, and the airway at the throat is composed of walls of soft tissue, which can collapse, it is not surprising that breathing can be obstructed during sleep. Although a minor degree of OSA is considered to be within the bounds of normal sleep, and many individuals experience episodes of OSA at some point in life, a small percentage of people have chronic, severe OSA.
Scope of the Report:
Market Access strategy for different payer archetypes
Segmentation and mapping of payers to different archetypes based on their specific criteria of assessment i.e. costeffectiveness, budget impact, clinical effectiveness. This would enable designing effective market strategy for reimbursement in these markets. It also covers the reimbursement decisions and benefit ratings of competitor drugs by different health technology assessment bodies in EU5,US and Japan.
Payer Policy changes and implications
Provides an overview of the changing payer preferences, concerns and evolving requirements. Informs about the payer policies impacting the prescription and uptake of particular product. Estimates the future payer environment and drivers of change.
Innovative pricing and funding mechanisms
With increasing pressure from payers and limitations in evidence development, many innovative payment mechanisms are being introduced such as outcome based reimbursement, annuity based funding etc. This section provides examples of such innovative models and feasibility of their application in a particular disease scenario.
Disease Overview
This report contains comprehensive overview of disease including disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends, as well as details about treatment algorithms and treatment guidelines
Epidemiology
This section encompasses information on the incidence and prevalence of disease in EU5, US Japan.
Existing and upcoming treatment landscape
Captures the evolution of treatment paradigm including the current and emerging drug therapies. Provides information on the clinical trial results, mechanism of action, route of administration, therapeutic positioning and regulatory milestones. It gives insight into the potential therapeutic targets for drug development.
Market Trends Unmet needs
This section of the report helps to understand the market trend and opportunities by analysing the impact of current therapies on the market, current and future unmet needs, drivers and barriers and demand of better technology. This is determined by analysing the impact of various factors such as mechanism of action, route, cost of therapy, patient segmentation, existing available treatments, compliance and need of the market, expected launch timelines, competitors, brand value and KOLs perception.
Major highlights of the report
Detailed analysis of existing and upcoming competitive landscape
HTA decisions and benefit ratings for :
NICE UK
GBA Germany
HASASMR and SMRFrance
AIFA Italy
AEMPS Spain
SMC Scotland
ICER US
Chuikyo Japan
Market archetyping and product positioning
Case studies on innovative funding models
Unmet need, major barriers and drivers across the industry:
Value story for achieving reimbursement and premium pricing in different markets