After an excellent start, Manchester United were undone twice in four minutes by Messi, who first nicked the ball off the careless Ashley Young and then watched as a weak shot from distance squirmed underneath David de Gea.

UEFA Champions League: Twitter reacts as Barcelona ease past Manchester United
Paul Pogba (Pic/ Twitter)

Lionel Messi pounced on two Manchester United mistakes to score twice and end their hopes of another comeback at Camp Nou as Barcelona breezed into the Champions League semi-finals on Tuesday.

After an excellent start, United were undone twice in four minutes by Messi, who first nicked the ball off the careless Ashley Young and then watched as a weak shot from distance squirmed underneath David de Gea.

Philippe Coutinho, in perhaps his best performance of the season, added a third with a curling effort into the top corner and by the end, an outclassed United might have been relieved the score was not more traumatic than 3-0, 4-0 on aggregate.

"We had five uncomfortable minutes because they came out strong," said Barcelona coach Ernesto Valverde. "But then there were another 85 minutes where we weren't bad."

A dizzying opening spell, in which Marcus Rashford had hit the crossbar, was long-forgotten, even if it could offer Barca's next opponents some encouragement.

Liverpool, who take a 2-0 lead to Porto on Wednesday, are now the most likely obstacle between them and their first Champions League final since they last won this tournament in 2015. Mohamed Salah and Sadio Mane might feel emboldened.

Instead, United's pair of early errors made this another night about Messi and ensured any faint hopes of repeating the comeback against Paris Saint-Germain, or even the famous 1999 rescue act against Bayern Munich, on this same pitch, were dashed.

"We said all along this was not going to change overnight," United's coach Ole Gunnar Solskjaer said.

"In the next few years it is going to be a massive effort to get to the level of Barcelona and these sorts of teams."

Messi now has his 109th and 110th Champions League goals and, potentially, three extra matches to reduce the gap on Cristiano Ronaldo's 126, after Juventus were dumped out by Ajax. Barcelona's fans celebrated that too.

Solskjaer had urged his strikers to be more lethal here but it felt ominous that even before kick-off, Rashford, Anthony Martial, Romelu Lukaku and Alexis Sanchez had hit 42 goals this season, while Messi on his own had 43.

Around an hour before kick-off, Alex Ferguson was on the side of the pitch, shaking hands with Ryan Giggs and sharing words with Solskjaer, the scorer of the winning goal against Munich here 20 years ago.

They could have hardly have asked for a better start. United were brilliant for eight minutes and could have been ahead within 30 seconds as Rashford raced onto a curving Paul Pogba pass and toed away a shot, which Marc-Andre ter Stegen bravely left to graze his own crossbar.

- Lionel Messi -
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Barca were flustered, so much so the crowd even cheered with relief when Arthur Melo played his team's first convincing pass.

Then, Barcelona had their own eight-minute flurry as United almost conceded a penalty, ruled out after Fred took the ball before bringing down Ivan Rakitic, and then did concede, twice, to Messi.

Both could have been avoided, even if Young's turn on the edge of his own box was punished in devastating fashion. Young lunged in to atone for his mistake but Messi skipped away from him, poked it through Fred's legs and then whipped the ball into the corner.

The second was simpler. Fred and Scott McTominay closed in on Coutinho and the ball spilled out to Messi, whose dribbling shot with his right foot should have drawn a routine save. Instead, De Gea let it squirm under his body for 2-0.

Pogba lashed out at the increasingly influential Arthur and Barca could have had a third before half-time, De Gea scrambling across to save on the line when Sergi Roberto should have finished.

Messi could have had his hat-trick too after Luis Suarez found him with a superb cutback and there was an almost comical sequence in the second half when the Argentinian played with his United chasers before finally being bundled over by McTominay.

Rashford might have made it interesting if he had controlled Pogba's ball over the top but Barcelona were in exhibition mode, helped by a vintage Coutinho curler after he had cut inside from the left.

Messi even attempted a bicycle kick and there were celebrations from the home fans when news went round that Ajax had taken the lead in Turin. They believe this is their year.

Here is how the fans on Twitter reacted to the match:

Man Utd’s defence before playing Barcelona tonight vs Man Utd’s defence after facing Barcelona tonight... pic.twitter.com/PrLNMxrGwr

— talkingbaws.com (@talkingbawscom) April 16, 2019

In case you missed the Barca vs Man Utd match last night, here are the highlights 🙂 pic.twitter.com/3RvzSZm9Db

— Èl-făntăstïçø (@sparkmore01) April 17, 2019

Barca vs Man utd. VAR should check if there is groundnut oil on the ball. Lwkmd

— Da'silva Omatseye (@omatseye2002) April 16, 2019

@FCBarcelona 0 vs @ManUtd 2
87minutes...
Me and my Guy: pic.twitter.com/dcX1eqW5AR

— Bukky_Show (@Bukola_Braid) April 16, 2019

Drake pictured wearing Barça jersey, Today is Barcelona vs Man Utd, UCL 2nd leg fixture.

If you know what I mean
🚶🏾‍♂ï¸Â pic.twitter.com/hPT01D2TM5

— iHumphreys (@MropeHumphreys) April 16, 2019

#DRAKE min 45" @ManUtd vs @FCBarcelona

🤣🤣🤣🤣🤣 pic.twitter.com/01mS3Jnf23

— Scr3aM ❁ (@Scr3am_Twitch) April 16, 2019

This @Drake Effect is about to taken seriously after today's @ManUtd Vs @FCBarcelona pic.twitter.com/0bn6qI3RDP

— Rafabscapuchu (@TomanyaG) April 10, 2019

The argument is not about who is GOAT. The argument now is whether Messi human or not. pogba's face says it all.😂#BARMUN pic.twitter.com/gXMb9a7Zly

— ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ãÂ…¤ ãÂ…¤ ãÂ…¤ ãÂ…¤ (@exlsior) April 17, 2019

"I know messi weakness" 😂😂😂😂😂#BARMUN pic.twitter.com/s36RxPel62

— Jay kiluu (@kiluujay) April 17, 2019

#BARMUN
De Gea saves Messi kick 😂😂 pic.twitter.com/bJjDWmtbzt

— Calebwizzy🗼 (@calebwaswa2) April 17, 2019

Fred: I can't see the ball.
Jones: stay back this is big boys thing.
Smalling: I can see the ball Fred.
Rakitic: bros free them, they can't catch today. #Messi, #BARMUN pic.twitter.com/usZiiLlcfu

— John Ekoh, Esq (@ekohjon) April 17, 2019

What can you say about Manchester United? It was easy tonight. Maybe the players need to spend more time on the training ground & less time in front of the mirror dancing and talking on social media" Messi #BARMUN pic.twitter.com/UfuFXq82rA

— Not the bae's boo👨 (@wyatt_lyric) April 17, 2019

In case you missed Barcelona and Manchester United match this is the highlight #BARMUN pic.twitter.com/K48AfAbl8n

— 🎲 ValDice 🎲 (@puffdice) April 16, 2019

Solskjaer looks like a little boy who lied about his height to get on the ghost train, and now he's scared the dip is coming#BARMUN

— Olukadaniel🇺🇬ðŸ¥Â‡ðŸ† (@OlukaDaniel5) April 17, 2019

And then Young, Smalling and Jones will call themselves professional footballers too😒😢 #BARMUN pic.twitter.com/7yPBBOe7n8

— Habeebullah (@Habeebullaaah) April 16, 2019

#BARMUN #BARMUN
comementator: lovely ball from messi to alba. Alba to coutinho
Coutinho: pic.twitter.com/nOKuJgetSx

— Wilde Chege (@ChegeWilde) April 16, 2019

Disgusting scenes at The Nou Camp as stewards force Man Utd fans to stay and watch the game #BARMUN pic.twitter.com/4PMYxtxehs

— BenchWarmers (@BeWarmers) April 16, 2019

De Gea looking at Chris Smalling, Ashley Young and Phil Jones on the way back to England.#BARMUN pic.twitter.com/p9Z1Kq2S7g

— The Kingmaker ðŸ¦Â‰ðŸ•Š (@SmithVinci) April 16, 2019

When you can't blame Mourinho 😂😂😂#BARMUN pic.twitter.com/atC8WeOUpK

— Dre Sips Tea ❁ (@Electric_Dre) April 16, 2019

Liverpool fans when they see Coutinho bang in a cracker against United! #BARMUN pic.twitter.com/SErvycLotN

— BenchWarmers (@BeWarmers) April 16, 2019

Them: Messi Won't survive in EPL.

Them: EPL teams are the best.

Messi: #BARMUN pic.twitter.com/FWvlxECgL0

— KING_satchmo (@king_satchmo) April 16, 2019