A pedestrian has died after being hit by a truck at an intersection in Brisbane's south on Monday.

Police said the 49-year-old woman was hit about 10.30am while crossing Beaudesert Road at the intersection of Nottingham Road at Calamvale.

Emergency services raced to the scene but paramedics declared her dead upon arrival.

Police closed part of the intersection on Monday, with traffic not able to turn right onto Nottingham Road, while investigators examined the scene.

The 46-year-old man who was driving the truck was assisting police with their inquiries.

Forensic Crash Unit was investigating and has appealed for anyone with information or dashcam footage of the incident to come forward.