Queensland police are at a crime scene in Brisbane's south after a man was fatally stabbed overnight.

The wounded Mount Gravatt resident was left at the QEII Jubilee Hospital at Coopers Plain on Troughton Road about 10.30pm on Saturday.

Police said attempts were made to treat the man’s injury but he died just after midnight.

Mount Gravatt detectives and a homicide squad were investigating the crime scene at Wishart, according to other media outlets.

Anyone with information in relation to the incident was urged to contact Policelink on 131 444 or Crime Stoppers on 1800 333 000.