Monthly News Roundup - February 2019

Cablivi is First Approval for Rare Blood Clotting Disorder

In February, the U.S. Food and Drug Administration (FDA) cleared Cablivi (caplacizumab-yhdp) injection from Ablynx, the first treatment approved in combination with plasma exchange and immunosuppressive therapy for adults with acquired thrombotic thrombocytopenic purpura (aTTP), a rare and life-threatening disorder that causes blood clotting.

Novo Nordisk’s Esperoct Cleared for Hemophilia A Prophylaxis

This month the FDA also approved Novo Nordisk’s Esperoct (turoctocog alfa pegol, N8-GP) for treatment of hemophilia A (congenital factor VIII deficiency) in adults and children. Hemophilia A can cause severe bleeding into the large joints such as the knees or hips.

Egaten Available for Fascioliasis, a Neglected Tropical Disease

Fascioliasis, commonly known as liver fluke infestation, infects 2.4 million people worldwide and occurs following ingestion of the larvae in food or water. The FDA has now approved Egaten (triclabendazole), a benzimidazole anthelmintic, for the treatment of fascioliasis in patients six years of age and older.

Gloperba is First Oral Colchicine Solution to Prevent Gout Flares

Gout is a painful type of arthritis that afflicts roughly 8.7 million people in the U.S. It is caused by elevated levels of uric acid crystals in the joints and can be treated with colchicine.

Jeuveau Approved to Lessen the Appearance of Frown Lines

Jeuveau (prabotulinumtoxinA) is a botulinum toxin type A formulation okayed this month for injection into the facial muscles to lessen moderate to severe frown lines between the eyebrows (glabellar lines).

Posted: February 2019