Addition of IV acetaminophen with propofol or dexmedetomidine reduces risk of postoperative delirium in older patients undergoing cardiac surgery

Addition of IV acetaminophen with propofol or dexmedetomidine reduces risk of post-operative delirium in older patients undergoing cardiac surgery

15:02 EST 19 Feb 2019 | 2 Minute Medicine

1. In this randomized controlled trial, post-operative scheduled intravenous (IV) acetaminophen combined with propofol or dexmedetomidine reduced risk of post-operative delirium in older patients undergoing cardiac surgery compared to placebo. 2. The combination with IV acetaminophen also significantly reduced delirium duration, ICU length of stay, and breakthrough analgesia compared with placebo. Evidence Rating Level: 1 […]

Source: 2 Minute Medicine

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