Hyperactivity in Neurons Deficient in a Specific Gene Associated with Autism

09:09 EST 13 Feb 2019 | Genetic Engineering News

Scientists have described the impacts of neuronal mutations on autism-related characteristics in humans in open-access article (“CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks”) in eLife. “Induced pluripotent stem cell (iPSC)-derived neurons are increasingly used to model Autism Spectrum Disorder (ASD), which is clinically and genetically heterogeneous. To study the complex […]

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