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Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for January 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
THURSDAY, Jan. 31, 2019 -- Projected increases in maternal heat exposure may result in increased congenital heart defect (CHD) burden, according to a study published online Jan. 30 in the Journal of the American Heart Association.
THURSDAY, Jan. 31, 2019 -- The first generic form of the Advair Diskus (fluticasone propionate and salmeterol inhalation powder) inhaler has been approved by the U.S. Food and Drug Administration.
THURSDAY, Jan. 31, 2019 -- Receipt of primary care is associated with significantly more high-value care, slightly more low-value care, and a better health care experience, according to a study published online Jan. 28 in JAMA Internal Medicine.
WEDNESDAY, Jan. 30, 2019 -- The U.S. Food and Drug Administration was given an "F" in a new American Lung Association report card evaluating tobacco prevention programs.
WEDNESDAY, Jan. 30, 2019 -- An expanded recall of ibuprofen oral suspension drops that may contain higher-than-specified levels of ibuprofen that could harm infants' kidneys has been announced by Tris Pharma, Inc.
WEDNESDAY, Jan. 30, 2019 -- The proportion of fractures/dislocations, lower-extremity fractures, fractures in adults, and surgical interventions is higher for injuries associated with jump parks versus home trampolines, according to a study published in the Jan. 1 issue of the Journal of the American Academy of Orthopaedic Surgeons.
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WEDNESDAY, Jan. 30, 2019 -- Omega-3 fatty acid (n3PUFA) supplements do not appear to improve asthma control in teens and young adults who are overweight or obese, according to a study published online Jan. 25 in the Annals of the American Thoracic Society.
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TUESDAY, Jan. 29, 2019 -- From 1976 to 2016, there was a decrease in the proportion of families who had young children and owned firearms, although an increase was seen in the proportion who owned handguns, according to a study published online Jan. 28 in Pediatrics.
TUESDAY, Jan. 29, 2019 -- The U.S. Preventive Services Task Force (USPSTF) has reaffirmed the recommendation for use of ocular prophylaxis for gonococcal ophthalmia neonatorum. This recommendation forms the basis of a final recommendation statement published online Jan. 29 in the Journal of the American Medical Association.
TUESDAY, Jan. 29, 2019 -- Only one in five children and adults with type 1 diabetes (T1D) in the United States achieve American Diabetes Association (ADA) goals for glycated hemoglobin (HbA1c), according to a study published online Jan. 18 in Diabetes Technology & Therapeutics.
MONDAY, Jan. 28, 2019 -- A statewide public health emergency was declared in Washington after a measles outbreak near Portland, Oregon, reached 31 cases on Friday. The outbreak in the Pacific Northwest is in what has been called an antivaccination "hot spot" in the United States, the Associated Press reported.
MONDAY, Jan. 28, 2019 -- Screen time is associated with poorer performance on developmental screening tests among young children, according to a study published online Jan. 28 in JAMA Pediatrics.
MONDAY, Jan. 28, 2019 -- During 2009 through 2018, multiple-victim school-associated homicide rates increased significantly, while single-victim homicide rates remained stable from 1994 through 2016, according to research published in the Jan. 25 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
MONDAY, Jan. 28, 2019 -- Adolescents with higher levels of conduct disorder symptoms and greater rates of depressive symptoms have increased odds of reporting participation in the choking game, in which pressure is applied to the carotid artery to temporarily limit blood flow and oxygen, according to a study published online Jan. 28 in Pediatrics.
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MONDAY, Jan. 28, 2019 -- Children born by medically assisted reproduction have an increased risk for adverse birth outcomes; however, the increased risk appears to be attributable to other factors, according to a study published online Jan. 14 in The Lancet.
FRIDAY, Jan. 25, 2019 -- Higher lean body mass during childhood and adolescence is associated with higher lung function at age 15 years for both sexes, according to a study published online Jan. 11 in the American Journal of Respiratory and Critical Care Medicine.
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THURSDAY, Jan. 24, 2019 -- Higher childhood blood lead levels are associated with more psychopathology during the life course, according to a study published online Jan. 23 in JAMA Psychiatry.
FRIDAY, Jan. 25, 2019 -- An improved type 1 diabetes (T1D) genetic risk score (GRS), the T1D GRS2, is highly useful for classifying adult incident diabetes type and improving newborn screening, according to a study published in the February issue of Diabetes Care.
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FRIDAY, Jan. 25, 2019 -- In a report published in the January issue of Value in Health, an ISPOR--The Professional Society for Health Economics and Outcomes Research working group indicates the lack of good practices in three areas of health technology assessment (HTA).
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FRIDAY, Jan. 25, 2019 -- Many adolescents do not complete human papillomavirus (HPV) vaccination before turning 13 or 15 years old, according to a report published online Jan. 17 in the Journal of Infectious Diseases.
THURSDAY, Jan. 24, 2019 -- The average annual cost of inpatient hospitalizations for firearm injury exceeded $911 million from 2010 to 2015, with 9.5 percent of that amount due to readmissions, according to a study published online Jan. 24 in PLOS ONE.
THURSDAY, Jan. 24, 2019 -- An ongoing measles outbreak has led to a public health emergency being declared in Clark County, Washington.
THURSDAY, Jan. 24, 2019 -- A hospital-based initiative in Southern states is associated with increases in breastfeeding rates among African-American infants, according to a study published online Jan. 18 in Pediatrics.
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WEDNESDAY, Jan. 23, 2019 -- For patients with fragile X syndrome (FXS), mavoglurant treatment improves visual attention and pupil reactivity, according to a study published online Jan. 17 in PLOS ONE.
WEDNESDAY, Jan. 23, 2019 -- From 2006 to 2017, there was a decrease in 4-valent vaccine-type human papillomavirus (HPV) detection among vaccinated and unvaccinated women, according to a study published online Jan. 22 in Pediatrics.
WEDNESDAY, Jan. 23, 2019 -- For some children with hypodiploid acute lymphoblastic leukemia (ALL), allogeneic hematopoietic cell transplantation does not improve outcomes compared with chemotherapy alone, according to a study published online Jan. 18 in the Journal of Clinical Oncology.
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TUESDAY, Jan. 22, 2019 -- Over time, the prevalence of gastroschisis has increased, with more babies born with gastroschisis in areas with high and medium versus low opioid prescription rates, according to research published in the Jan. 18 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
TUESDAY, Jan. 22, 2019 -- Sales of electronic cigarettes could be halted if companies do not stop marketing the devices to youth, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., warned.
TUESDAY, Jan. 22, 2019 -- Providing information on the benefits of vaccination, including cancer prevention, and avoiding expressing urgency to vaccinate can increase parent confidence in human papillomavirus (HPV) vaccination, according to a study published online Jan. 22 in Pediatrics.
TUESDAY, Jan. 22, 2019 -- Guidelines have been developed for the management of severe atopic dermatitis (AD); the recommendations have been published as a clinical management review in the January issue of The Journal of Allergy and Clinical Immunology: In Practice.
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TUESDAY, Jan. 22, 2019 -- Primary care providers are well positioned to provide critical support and personalized care for youth with gender dysphoria and their caregivers or families, according to a review published online Jan. 21 in CMAJ, the journal of the Canadian Medical Association.
TUESDAY, Jan. 22, 2019 -- Wearable sensor data extracted from a fear induction task paired with machine learning can accurately identify young children with internalizing diagnosis, according to a study published online Jan. 16 in PLOS ONE.
TUESDAY, Jan. 22, 2019 -- Whole-exome sequencing (WES) can identify a genetic cause for almost one-third of pediatric kidney transplant recipients, according to a study published online Jan. 17 in the Journal of the American Society of Nephrology.
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FRIDAY, Jan. 18, 2019 -- Therapists implementing interpersonal psychotherapy for depressed adolescents (IPT-A) should routinely monitor depression symptoms and consider augmenting treatment for insufficient responders as early as week 4 of treatment, according to a study published in the January issue of the Journal of the American Academy of Child & Adolescent Psychiatry.
FRIDAY, Jan. 18, 2019 -- Mandated neonatal abstinence syndrome (NAS) surveillance and reporting allows state health departments to quantify incidence and informs programs and services, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
FRIDAY, Jan. 18, 2019 -- Trained alert dogs can help patients with type 1 diabetes regulate their blood glucose levels, according to a study published online Jan. 15 in PLOS ONE.
FRIDAY, Jan. 18, 2019 -- Less than half of all outpatient antibiotic prescription fills by privately insured nonelderly adults and children in the United States are appropriate or potentially appropriate, according to a study published online Jan. 16 in The BMJ.
FRIDAY, Jan. 18, 2019 -- A U.S. Food and Drug Administration advisory panel vote on whether to recommend approval of the first oral medication for type 1 diabetes ended in an 8-8 tie Thursday.
THURSDAY, Jan. 17, 2019 -- The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.
THURSDAY, Jan. 17, 2019 -- Vaccine hesitancy is among the top 10 health threats facing the world in 2019, the World Health Organization says.
THURSDAY, Jan. 17, 2019 -- Due to the federal government shutdown, the U.S. Food and Drug Administration has only about five weeks of funding left to review new drug applications, according to Commissioner Scott Gottlieb, M.D.
THURSDAY, Jan. 17, 2019 -- Most children younger than 2 years with bronchiolitis seen in U.S. emergency departments and prescribed antibiotics have no documented bacterial coinfection, according to a study published online Jan. 17 in the Journal of the Pediatric Infectious Diseases Society.
THURSDAY, Jan. 17, 2019 -- Adolescent sports-related concussion (SRC) is associated with temporary impairments in health-related quality of life (HRQOL), according to a study published online Jan. 15 in the Journal of Neurosurgery: Pediatrics.
THURSDAY, Jan. 17, 2019 -- The prevalence of undiagnosed asthma is 20.2 percent among urban adolescents, according to a study published online Jan. 15 in the Journal of Urban Health.
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THURSDAY, Jan. 17, 2019 -- Achieving a healthy diet from sustainable food systems is feasible but will require considerable shifts toward healthy dietary patterns, according to a report from the EAT-Lancet Commission published online Jan. 16 by The Lancet.
THURSDAY, Jan. 17, 2019 -- Two patients diagnosed with acute flaccid myelitis and upper-extremity neuropathy who were treated with peripheral nerve transfer continue to demonstrate functional recovery at two years, according to a case series recently published in Pediatric Neurology.
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WEDNESDAY, Jan. 16, 2019 -- Many low-income women cannot afford menstrual hygiene supplies, according to a study published online Jan. 8 in Obstetrics & Gynecology.
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WEDNESDAY, Jan. 16, 2019 -- Adoption of advanced health information technology (HIT) capabilities is inconsistent across health care systems, with electronic health record (EHR) standardization being the strongest predictor of advanced capabilities, according to a study published in the January issue of the American Journal of Managed Care.
WEDNESDAY, Jan. 16, 2019 -- A new review, published in the Jan. 15 issue of the Journal of the American Medical Association, addresses best practices for the evaluation and management of reported penicillin allergies.
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WEDNESDAY, Jan. 16, 2019 -- Clinicians perceive accidental dislodgement of intravenous (IV) devices to be a common occurrence, according to a study published in the December issue of the Journal of the Association for Vascular Access.
TUESDAY, Jan. 15, 2019 -- Routine inspections of riskier foods will resume as early as today, the U.S. Food and Drug Administration says.
TUESDAY, Jan. 15, 2019 -- Ethical principles are discussed in an updated Ethics Manual, issued by the American College of Physicians (ACP) and published as a supplement to the Jan. 15 issue of the Annals of Internal Medicine.
TUESDAY, Jan. 15, 2019 -- The influence of heritability and environmental factors has been identified for a large number of phenotypes, according to a study published online Jan. 14 in Nature Genetics.
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TUESDAY, Jan. 15, 2019 -- Recalling specific positive life experiences may build resilience and help lower vulnerability to depression among adolescents with a history of early-life stress, according to a research letter published online Jan. 14 in Nature Human Behaviour.
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TUESDAY, Jan. 15, 2019 -- Delayed contraceptive initiation is associated with unwanted pregnancy within three months of sexual debut, according to a study published online Jan. 15 in Pediatrics.
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MONDAY, Jan. 14, 2019 -- The Substance Abuse and Mental Health Services Administration national helpline (800-662-HELP) seems to be underappreciated in the media and by the general population, according to a research letter published online Jan. 14 in JAMA Internal Medicine.
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MONDAY, Jan. 14, 2019 -- Topical application of a transient receptor potential vanilloid subfamily, member 1 (TRPV1) antagonist may be an effective and safe treatment for patients with mild-to-moderate atopic dermatitis (AD), according to a phase IIb study published online Jan. 8 in the British Journal of Dermatology.
MONDAY, Jan. 14, 2019 -- The introduction of emergency department- or community-based pharmacists with an expanded scope of practice may cut emergency department overcrowding, according to a study recently published in Research in Social and Administrative Pharmacy.
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MONDAY, Jan. 14, 2019 -- There is a high prevalence of parental unawareness and adolescent denial of suicidal thoughts, according to a study published online Jan. 14 in Pediatrics.
FRIDAY, Jan. 11, 2019 -- About half of adolescent and young adult (AYA) patients report having had private time with a health care provider (HCP) and having spoken to an HCP about confidentiality, according to a study published online Jan. 9 in the Journal of Adolescent Health.
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FRIDAY, Jan. 11, 2019 -- The flu season is picking up steam, with about 7 million Americans having been struck by a strain of the flu virus, health officials said Friday.
FRIDAY, Jan. 11, 2019 -- Pregnant women with 2009 H1N1 influenza admitted to an intensive care unit (ICU) have an increased risk for adverse birth outcomes, according to a study published online Jan. 9 in Birth Defects Research.
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FRIDAY, Jan. 11, 2019 -- The difference in health spending between the United States and other countries is still explained by health care prices, according to a study published in the January issue of Health Affairs.
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THURSDAY, Jan. 10, 2019 -- The Escherichia coli outbreak linked to California-grown romaine lettuce appears to be over, the U.S. Centers for Disease Control and Prevention said Wednesday.
THURSDAY, Jan. 10, 2019 -- Food inspections have declined due to the partial shutdown of the U.S. government, potentially putting the nation's food supply at risk.
THURSDAY, Jan. 10, 2019 -- Secondhand exposure to electronic nicotine delivery systems (ENDS) aerosols may be related to asthma symptoms in youth, according to a study published in the January issue of CHEST.
THURSDAY, Jan. 10, 2019 -- Influenza vaccination during hospitalization is associated with reduced risk for readmission, outpatient visits, fever, and clinical evaluations for infection postdischarge, according to a study published online Jan. 8 in the Mayo Clinic Proceedings.
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THURSDAY, Jan. 10, 2019 -- The phenomenon of private equity acquisition of physician practices is discussed in an Ideas and Opinions piece published online Jan. 8 in the Annals of Internal Medicine.
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WEDNESDAY, Jan. 9, 2019 -- There have been at least 112 confirmed cases of measles in Rockland and Orange counties and at least 55 in New York City in what officials say is the largest measles outbreak in New York state in recent history.
WEDNESDAY, Jan. 9, 2019 -- Combined modality treatment (CMT) is associated with improved overall survival in pediatric patients with early-stage Hodgkin lymphoma (HL), according to a study published online Jan. 3 in JAMA Oncology.
WEDNESDAY, Jan. 9, 2019 -- Many U.S. female health care workers, particularly women of color, live in poverty and lack health insurance, according to a study published online Dec. 20 in the American Journal of Public Health.
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WEDNESDAY, Jan. 9, 2019 -- The costs of oral and injectable brand-name drugs increased from 2008 to 2016, with most of the increase due to existing drugs, while new drugs accounted for cost increases in specialty and generic drugs, according to a study published in the January issue of Health Affairs.
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WEDNESDAY, Jan. 9, 2019 -- Depressive symptoms are prevalent among urban teens with asthma and are associated with worse outcomes, according to a study published online Dec. 19 in Academic Pediatrics.
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TUESDAY, Jan. 8, 2019 -- From 1997 through 2016, there was an increase in medical marketing, especially direct-to-consumer (DTC) advertising, according to research published in the Jan. 1/8 issue of the Journal of the American Medical Association.
TUESDAY, Jan. 8, 2019 -- The U.S. Preventive Services Task Force (USPSTF) recommends hepatitis B virus (HBV) infection screening in pregnant women at their first prenatal visit. These findings form the basis of a draft recommendation statement published online Jan. 8 by the task force.
TUESDAY, Jan. 8, 2019 -- Certain genetic diseases can be detected by new artificial intelligence technology that analyzes a photo of a person's face, according to a study published online Jan. 7 in Nature Medicine.
TUESDAY, Jan. 8, 2019 -- Most emergency visits by children occur at nonpediatric emergency departments, which have more frequent antibiotic prescribing, according to a study published online Jan. 8 in Pediatrics.
TUESDAY, Jan. 8, 2019 -- Strict local tobacco retail licensing (TRL) regulation may lower rates of cigarette and electronic cigarette use among youth and young adults, according to a study published online Jan. 7 in Pediatrics.
TUESDAY, Jan. 8, 2019 -- For extremely preterm infants, the use of single-family rooms is associated with reduced sepsis incidence and improvements in breastfeeding rates during hospital stays but with no difference in long-term neurodevelopment, according to a review published online Jan. 7 in The Lancet Child & Adolescent Health.
TUESDAY, Jan. 8, 2019 -- Children receiving invasive mechanical ventilation for ≥48 hours often experience muscle atrophy, especially in the diaphragm, according to a study published online Dec. 19 in PLOS ONE.
TUESDAY, Jan. 8, 2019 -- The overall cancer death rate decreased continuously by 27 percent from 1991 to 2016, according to a report published online Jan. 8 in CA: A Cancer Journal for Clinicians.
TUESDAY, Jan. 8, 2019 -- Eliminating the Affordable Care Act's individual mandate penalty is unlikely to destabilize the individual market in California but could roll back coverage gains, according to a study published in the January issue of Health Affairs.
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MONDAY, Jan. 7, 2019 -- Screening donated blood for Zika virus is cost-effective only in the high mosquito season in Puerto Rico, according to a study published online Jan. 8 in the Annals of Internal Medicine.
MONDAY, Jan. 7, 2019 -- An approach involving a combination of provider report and pharmacy refill data can improve identification of medication nonadherence among youth with chronic kidney disease (CKD), according to a study published in the January issue of Pediatric Nephrology.
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MONDAY, Jan. 7, 2019 -- The quadrivalent live attenuated influenza vaccine (LAIV4) is less effective than inactivated influenza vaccine (IIV) against influenza A/H1N1pdm09 in all pediatric age groups, according to research published online Jan. 7 in Pediatrics.
MONDAY, Jan. 7, 2019 -- Survivors of childhood Hodgkin lymphoma (HL) remain at increased risk for developing subsequent malignant neoplasms (SMNs), according to research published online Dec. 17 in Cancer.
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MONDAY, Jan. 7, 2019 -- In adolescent patients with Duchenne muscular dystrophy (DMD), use of a handheld device (HHD) to assess pulmonary function at home is feasible and provides reliable data, according to an analysis recently published in the Journal of Neuromuscular Diseases.
FRIDAY, Jan. 4, 2019 -- There is no compelling evidence to indicate health benefits of nonsugar sweetener (NSS) use on a range of health outcomes, according to a review published online Jan. 2 in The BMJ.
FRIDAY, Jan. 4, 2019 -- Use of the antiepileptic drug (AED) valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD) among offspring, according to a study published online Jan. 4 in JAMA Network Open.
FRIDAY, Jan. 4, 2019 -- Most persons with Down syndrome (DS) maintain their personal hygiene by age 13 years and work independently by 20 years, according to a study published online Dec. 24 in the American Journal of Medical Genetics.
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FRIDAY, Jan. 4, 2019 -- Body mass index (BMI) increases in middle school students can be limited by school-based nutrition policies but not by physical activity policies, according to a study published in the January issue of the American Journal of Preventive Medicine.
FRIDAY, Jan. 4, 2019 -- Both initiation and completion of the process of epiphyseal fusion (EF) are occurring earlier in children than they did a century ago, according to a study recently published in Clinical Orthopaedics and Related Research.
THURSDAY, Jan. 3, 2019 -- Newborn genomic sequencing (nGS) can detect the risk for disease onset during childhood and actionable adult-onset disease, according to a study published in the Jan. 3 issue of the American Journal of Human Genetics.
THURSDAY, Jan. 3, 2019 -- From 1999 to 2016, there was close to a threefold increase in the pediatric mortality rate from opioid poisonings in the United States, according to a study published online Dec. 28 in JAMA Network Open.
THURSDAY, Jan. 3, 2019 -- The global incidence of child pneumonia and related mortality decreased substantially from 2000 to 2015, consistent with decreases in the prevalence of some key risk factors, according to a study published in the January issue of The Lancet Global Health.
WEDNESDAY, Jan. 2, 2019 -- College students have an increased risk for sporadic and outbreak-associated serogroup B meningococcal disease, according to a study published online Dec. 31 in Pediatrics.
WEDNESDAY, Jan. 2, 2019 -- Smoking habits do not differ for adolescents with asthma or their parents versus those without asthma, according to a letter to the editor published online Dec. 4 in Allergy.
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WEDNESDAY, Jan 2, 2019 -- Examination limited to hands, feet, and lower legs has a sensitivity of about 90 percent for detecting scabies, according to a study published online Dec. 27 in PLOS Neglected Tropical Diseases.
Posted: February 2019