When Your Daughter Defies Biology

A reader contacted me under a pseudonym a few months ago. She turned out to be a prominent Southern lawyer with a problem she hoped I’d write about. Her college-age daughter had always been a “girly girl” and intellectually precocious, but had struggled with anxiety and depression. She liked boys and had boyfriends in high school, but also faced social challenges and often found herself on the outs with cliques.

The young woman went off to college—which began, as it often does these days, with an invitation to state her name,...