Opioids unlikely to provide clinically meaningful reduction in chronic noncancer pain

Opioids unlikely to provide clinically meaningful reduction in chronic non-cancer pain

1. In this systematic review and meta-analysis of patients with chronic non-cancer pain, though opioids showed small improvements in pain, physical functioning, and sleep quality, these differences did not meet minimally important standards and diminished with longer follow-up. 2. There was no difference in pain or physical functioning for opioids compared to NSAIDs or tricyclic […]

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