Mortality in head-and-neck squamous cell carcinoma has remained unaltered throughout the past and is predominantly associated with early onset of locoregional recurrence. Since the first publication of the beneficial use of checkpoint inhibitors in melanoma, patients have developed high hopes for the treatment of head-and-neck squamous cell carcinoma. To date, several checkpoint inhibitors are being evaluated in clinical studies testing diverse drug and treatment combinations at different timepoints of the disease.
Original Article: [Comment] PD-1 antibodies in head-and-neck cancer