“Victorians can see a Liberal-Nationals government will hit the ground running … to make our state more cost-effective and more affordable, to get back in control of population growth of congestion, of crime and indeed begin that long process to begin decentralisation,” he said.

The costings for the Opposition’s election promises would be released on Thursday, Mr Guy said.

“We’re not going to increase taxes like the Labor government,” he said.

On the promise to promptly shut down the North Richmond safe injecting room, Mr Guy said it was intolerable to have the facility next to a primary school.

“I wouldn’t want an ice injecting room next to my sons’ primary school and therefore I won’t tolerate it next to anyone else’s childrens’ primary school - that’s why we’ll shut it down,” he said.

The Andrews government released data in September showing staff at the facility had treated 140 people for overdoses within its first three months.

Premier Daniel Andrews hailed the trial a success when responding to Mr Guy's pledge on Wednesday.

"That trial is saving lives. To do otherwise means those lives won't be saved. It's very, very simple," he said.

Liberal health spokeswoman Mary Wooldridge said the Coalition would work with North Richmond Community Health on alternative help for heroin and ice users in the area.

The injecting room trial was recommended last year by a coroner investigating the overdose death of a 34-year-old woman who had frequently visited North Richmond to buy heroin.

The coroner’s report noted 34 people died heroin-related deaths in North Richmond in 2016.

At the time, heroin deaths had reached their highest rate for almost two decades, with 220 deaths in Victoria in 2017, and 80 deaths in the region encompassing North Richmond in the six years between 2012 and 2017.

The Coalition’s announcement has been blasted by the Australian Medical Association of Victoria, with its president Associate Professor Julian Rait dubbing it a "retrograde step".

"I’ve been there and I’m convinced it’s saving lives and assisting people who would otherwise be at the margins of society," Professor Rait said.

"I think we need to change our mindset about addiction being a crime [when it’s really] a health issue."

Mr Guy’s announcement is a broader pitch to Victorian voters, rather than locals, as the Liberal party is not running a candidate in the seat of Richmond, where Labor planning minister Richard Wynne will battle the Greens.

Richmond resident and surgeon Jill Tomlinson said she used to have to regularly call triple-zero for people who had collapsed unconscious on Victoria Street.

Since the injecting centre opened in July, she said she had encountered no one needing assistance.

The injecting room operates out of the North Richmond Community Health centre on Lennox Street where Dr Tomlinson also takes her nine-month-old daughter for appointments, but the surgeon said she felt safer in her community now with the injecting room open.

“I don’t think it exposes to children to greater risk. I think there is greater risk in not having it,” she said.

Dr Tomlinson said Matthew Guy’s promise was “bad policy”.

“Good policy is policy that saves lives and this policy will cost lives,” she said.

Another priority for the Coalition in the first 100 days would be reviewing the contracts for all "skyrail" level crossings to see if they can be modified.

Development Victoria - the agency the Andrews government appointed to work in secret to develop the $50 billion suburban rail loop - would be put in charge of choosing the best route for the East West Link.

The authority Labor set up to build the $15.8 billion North East Link toll road would be given the extra task of delivering the East West Link toll road, which Labor scrapped within its first 100 days in early 2015.

Victoria’s ambitious renewable energy targets would be scrapped early next year, while the tender process for subsidising energy efficient fridges and televisions for low income earners would begin.

The moratorium on conventional onshore gas exploration and extraction would be overturned through legislation next year, in a move the Opposition said would reduce household energy costs and be a jobs boon.