Articles Eicosapentaenoic acid and aspirin alone and in combination for the prevention of colorectal adenomas seAFOod Polyp Prevention trial a multicentre randomised doubleblind placebocontrolled 22 factorial trial

[Articles] Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial

Neither EPA nor aspirin treatment were associated with a reduction in the proportion of patients with at least one colorectal adenoma. Further research is needed regarding the effect on colorectal adenoma number according to adenoma type and location. Optimal use of EPA and aspirin might need a precision medicine approach to adenoma recurrence.

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