A combination of chemotherapy drug azacitidine and nivolumab (Bristol-Myers Squibb’s Opdivo) has proven effective in treating patients with relapsed or refractory acute myeloid leukaemia (AML) in a phase II trial, led by Professor Naval Daver the University of Texas MD Anderson Cancer Center.
The phase II trial demonstrated that 22% of the 70 patients went into complete remission following the combination treatment. While participants had on average already undergone two prior treatments for relapsed AML, the response rate was 33% overall.
Original Article: Azacitidine and nivolumab combo proves successful in phase II trial