Toulouse - Toulouse and Scotland suffered a blow on Monday with news that lock Richie Gray needs a back operation that will rule him out for "around four months".
Gray, capped 65 times by Scotland, will miss the November Tests and also at least the start of the Six Nations next year.
The 29-year-old, who previously went under the knife for a back injury in summer 2017, has only played 60 minutes of rugby this season, against Agen on October 6.
Scotland are due to host the Springboks at Murrayfield in Edinburgh on November 17.
Meanwhile, Toulouse coach Ugo Mola also confirmed that the Top 14 club and France would be without winger Yoann Huget (meniscus) for up to three weeks.
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