Quick Take Efficacy and safety of LY3298176 a novel dual GIP and GLP1 receptor agonist in patients with type 2 diabetes a randomised placebocontrolled and active comparatorcontrolled phase 2 trial

Quick Take: Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial

00:00 EDT 12 Oct 2018 | 2 Minute Medicine

Glucagon-like peptide-1 (GLP-1) potentiates the release of insulin from pancreatic beta cells in a glucose-dependent manner. While pharmacologic studies have shown that GLP-1 delays gastric emptying, reduces appetite, decreases food intake, and therefore, contributes to improved glucose homeostasis and bodyweight, some patients fail to achieve glycemic and bodyweight targets. LY3298176 is a novel dual glucose-dependent […]

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