The movie centers on the serial killer/nurse Charles Cullen. Redmayne would portray Cullen and Chastain would play a nurse who helped track down Cullen after he killed as many as 40 patients before being arrested in 2003, reports variety.com.
"The Good Nurse," based on the book by Charles Graeber, will be adapted by Krysty Wilson-Cairns. Danish helmer Tobias Lindholm will direct the project.
Redmayne, who won the best actor Oscar for "The Theory of Everything", will next be seen seen as Newt Scamander in "Fantastic Beasts: The Crimes of Grindelwald".
Chastain starred in "Molly's Game". She will appear in the X-Men film "Dark Phoenix" as an alien shapeshifter and will play the adult Beverly Marsh in "It: Chapter Two."
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