Muthuvel Karunanidhi, a champion of Dravidian politics and a five-time Tamil Nadu chief minister, has died. He was 94.
Chennai's Kauvery hospital said Karunanidhi, the leader of the Dravida Munnetra Kazhagam (DMK) party, died at 6:10 pm today.
"Despite the best possible efforts by our team of doctors and nurses to resuscitate him, he failed to respond. We profoundly mourn the loss of one of the tallest leaders of India and we share the grief of family members and fellow Tamilians worldwide," the hospital said.
The Tamil Nadu government announced a seven-day period of mourning, and a holiday tomorrow.
President Ram Nath Kovind said he was extremely sad to learn of Karunanidhi's passing. "Our country is poorer today," he tweeted.
Extremely sad to learn of the passing of Thiru M. Karunanidhi. A doyen of our public life, as a contributor to the development of Tamil Nadu and of India he has few peers. Our country is poorer today. My condolences to his family and millions of well-wishers #PresidentKovind
President of India (@rashtrapatibhvn) August 7, 2018
Prime Minister Narendra Modi said Karunanidhi "stood for regional aspirations as well as national progress. He was steadfastly committed to the welfare of Tamils and ensured that Tamil Nadu's voice was effectively heard."
"India, and particularly Tamil Nadu, will miss him immensely."
Deeply saddened by the passing away of Kalaignar Karunanidhi. He was one of the senior most leaders of India.
Narendra Modi (@narendramodi) August 7, 2018
We have lost a deep-rooted mass leader, prolific thinker, accomplished writer and a stalwart whose life was devoted to the welfare of the poor and the marginalised. pic.twitter.com/jOZ3BOIZMj
Karunanidhi largely stayed away from active politics since he underwent a surgery in 2016.
His death follows the demise of his arch-rival Jayalalithaa in 2016, bringing to an end an era when electoral fortunes swung, pendulum-like, to either of the these two political titans.
Now, the DMK will look to MK Stalin, one of Karunanidhi's sons, to lead the charge as Tamil Nadu prepares to vote in next year's general election. Stalin is already the party's working president.

Even in his nineties, Karunanidhi was still addressing public meetings; he once said even turning 100 wouldn't stop him from working for the people. He weathered all manner of challenges and setbacks -- including MG Ramachandran's expulsion from the DMK in 1972, and a squabble involving Stalin and another son, Azhagiri (whom Karunanidhi expelled).
His party has faced charges of corruption, beginning with the Sarkaria Commission's indictment in the late 1970s to the 2G spectrum case.
Scripting films, scripting a state's destiny

The DMK's "Kalaignar", meaning scholar of arts, was born Dakshinamurthy on June 3, 1924, in Thirukkuvalai, a village in present-day Tamil Nadu's Nagapattinam district. He would later credit "confidence" and "strong determination" for his rise from humble beginnings to high office.
Karunanidhi's life in politics began early. When he was just 14, he joined the Justice Party and a fledgling anti-Hindi agitation. When CN Annadurai split with EV Ramaswamy to form the DMK, Karunanidhi was one of its founding members.
A shrewd political mind wasn't Karunanidhi's only claim to fame; he was as potent with the pen as he was from the pulpit. In the 1950s, he began writing dialogue and screenplays for Tamil films.
GIFTED SCREENWRITER | What Kalaignar is to Tamil cinema
His debut was Sivaji Ganesan's Paraasakti, which features a court testimony -- "I ran, I ran" -- that has become something of an object of popular culture. He wrote historical and reformist stories propagating the Dravidian movement's socialist and rationalist ideals.
Rajinikanth, one of Tamil Nadu's most legendary actors, has called today a "black day" that he can never forget.
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Rajinikanth (@rajinikanth) August 7, 2018
Karunanidhi's debut in the Tamil Nadu legislature came in 1957; he was elected from a district where he led an agitation in support of local farm workers. Then, his rise was meteoric: Deputy leader of the Opposition in 1962, Annadurai's public works minister in 1967, and chief minister in 1969 (after Anna's death).
Karunanidhi prolonged his stint in the top post after an assembly election win in 1971. He would return to it three more times, in 1989, 1996 and 2006.
He is survived by his second and third wives, Dayalu and Rajathiammal, and six children - Muthu, Azhagiri, Stalin, Selvi, Thamizharasu and Kanimozhi.
VIDEO | Karunanidhi, five-time Tamil Nadu chief minister, dies
Inputs from PTI