University of Sunderland research into nanoparticle-based drug delivery systems is supporting the development of a new drug-candidate for treatment of triple negative breast cancer.The RAN-blocking peptide drug is being developed by a university consortium, led by Professor Mohamed El-Tanani at the University of Bradford and includes Ulster University, Queen’s University Belfast and University of Sunderland. Dr Ahmed Faheem at University of Sunderland Faculty of Health Sciences and Wellbeing is contributing his expertise in biodegradable nanoparticles for peptide delivery to engineer a series of nanoparticle to encapsulate the peptide. These peptide loaded nanoparticles have been shown, in vitro, to enter triple negative breast cancer cells, block RAN and reduce cell growth growth. The consortium is now developing in vivo models of triple negative breast cancer to allow further pre-clinical testing of the nanoparticles.
Original Article: Nanoparticle Drug Delivery at University of Sunderland