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Up to 30 people brawl with weapons in CBD

A 16-year-old boy was injured during a brawl involving up to 30 people, some armed with weapons, in Melbourne's CBD on Friday night.

Police had to use pepper spray to break up the fight on Bourke Street - near the corner of Russell Street - in one of the busiest areas of the city at about 7:30pm.

The teenager was taken to hospital with non-life threatening injuries after the fight, which police believe involved two separate groups of males.

Police say a variety of weapons were produced during the brawl, including batons and sticks.

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Police remained at the scene for about an hour questioning witnesses and people involved in the altercation. The entrance to the Target Centre in Bourke Street was closed for some time.

Trams down Bourke Street were diverted via La Trobe street while police dealt with the fallout from the fight.

Investigators are continuing to probe the circumstances surrounding the incident and have appealed for anyone with information to contact Crime Stoppers.

No arrests have been made.